2022
Disentangling the genetic basis of rhizosphere microbiome assembly in tomato
Oyserman B, Flores S, Griffioen T, Pan X, van der Wijk E, Pronk L, Lokhorst W, Nurfikari A, Paulson J, Movassagh M, Stopnisek N, Kupczok A, Cordovez V, Carrión V, Ligterink W, Snoek B, Medema M, Raaijmakers J. Disentangling the genetic basis of rhizosphere microbiome assembly in tomato. Nature Communications 2022, 13: 3228. PMID: 35710629, PMCID: PMC9203511, DOI: 10.1038/s41467-022-30849-9.Peer-Reviewed Original ResearchConceptsMicrobiome assemblyGenetic basisRhizosphere microbiome assemblyMetagenome-assembled genomesGene content analysisQuantitative trait lociDomestication sweepsDomesticated tomatoRhizosphere microbiomePutative plantPlant geneticsTrait lociBacterial genesPlant growthHybrid populationsQuantitative traitsBreeding programsMbp regionGenetic variation associatesPlant polysaccharidesDifferential recruitmentTomatoStreptomycesTraitsPivotal role
2018
Histopathological Image QTL Discovery of Immune Infiltration Variants
Barry J, Fagny M, Paulson J, Aerts H, Platig J, Quackenbush J. Histopathological Image QTL Discovery of Immune Infiltration Variants. IScience 2018, 5: 80-89. PMID: 30240647, PMCID: PMC6123851, DOI: 10.1016/j.isci.2018.07.001.Peer-Reviewed Original ResearchGenotype-Tissue ExpressionQuantitative traitsQuantitative trait lociGenotype-phenotype associationsVariant discoveryThyroid pathology imagesGenomic dataGenomic networksAssociation studiesTrait lociQTL dataQuantitative imaging biomarkersTissue length scalesMolecular readoutsImaging biomarkersClinical metadataGenomeImmune cell infiltrationQuantitative imaging featuresTXNDC5Hypothyroid datasetTraitsCell infiltrationVariantsMedical records