2022
A tumor volume and performance status model to predict outcome before treatment in diffuse large B-cell lymphoma
Thieblemont C, Chartier L, Dührsen U, Vitolo U, Barrington S, Zaucha J, Vercellino L, Silva M, Patrocinio-Carvalho I, Decazes P, Viailly P, Tilly H, Berriolo-Riedinger A, Casasnovas O, Hüttmann A, Ilyas H, Mikhaeel N, Dunn J, Cottereau A, Schmitz C, Kostakoglu L, Paulson J, Nielsen T, Meignan M. A tumor volume and performance status model to predict outcome before treatment in diffuse large B-cell lymphoma. Blood Advances 2022, 6: 5995-6004. PMID: 36044385, PMCID: PMC9691911, DOI: 10.1182/bloodadvances.2021006923.Peer-Reviewed Original ResearchConceptsLarge B-cell lymphomaAggressive large B-cell lymphomaB-cell lymphomaRisk factorsTumor volumePerformance statusDiffuse large B-cell lymphomaInternational Prognostic IndexMetabolic tumor volumeProgression-free survivalReal-world seriesReal-world clinicsREMARC trialOverall survivalRefractory diseaseECOG-PSPrognostic indexIntermediate riskInitial treatmentTreatment initiationRisk stratificationC-indexOlder patientsPrognostic toolClinical trialsCytomegalovirus infections in infants in Uganda: Newborn-mother pairs, neonates with sepsis, and infants with hydrocephalus
Hehnly C, Ssentongo P, Bebell L, Burgoine K, Bazira J, Fronterre C, Kumbakumba E, Mulondo R, Mbabazi-Kabachelor E, Morton S, Ngonzi J, Ochora M, Olupot-Olupot P, Mugamba J, Onen J, Roberts D, Sheldon K, Sinnar S, Smith J, Ssenyonga P, Kiwanuka J, Paulson J, Meier F, Ericson J, Broach J, Schiff S. Cytomegalovirus infections in infants in Uganda: Newborn-mother pairs, neonates with sepsis, and infants with hydrocephalus. International Journal Of Infectious Diseases 2022, 118: 24-33. PMID: 35150915, PMCID: PMC9058984, DOI: 10.1016/j.ijid.2022.02.005.Peer-Reviewed Original ResearchConceptsNewborn-mother pairsCMV prevalenceClinical sepsisCytomegalovirus infectionCerebrospinal fluidPrevalence of CMVQuantitative PCRCMV positivityPostinfectious hydrocephalusVaginal sheddingCMV infectionHIV seropositivityNeonatal ageMaternal ageMaternal vaginalRisk factorsMedical CenterLong-term consequencesMother pairsSepsisNeonatesInfantsPrevalenceHydrocephalusCMV
2021
Intraventricular haemorrhage in a Ugandan cohort of low birth weight neonates: the IVHU study
MacLeod R, Paulson J, Okalany N, Okello F, Acom L, Ikiror J, Cowan F, Tann C, Dyet L, Hagmann C, Burgoine K. Intraventricular haemorrhage in a Ugandan cohort of low birth weight neonates: the IVHU study. BMC Pediatrics 2021, 21: 12. PMID: 33407279, PMCID: PMC7786968, DOI: 10.1186/s12887-020-02464-4.Peer-Reviewed Original ResearchConceptsRisk of intraventricular haemorrhageLow birth weight neonatesIntraventricular haemorrhageNeonatal unitAntenatal steroidsOdds ratioGestational ageCranial ultrasoundRisk factorsProspective cohort study of neonatesAssociated with intraventricular haemorrhageCohort study of neonatesDoses of antenatal steroidsPrevention of intraventricular haemorrhageRates of SGA neonatesSeverity of intraventricular haemorrhageDay 7Study of neonatesProspective cohort studyLow-income countriesDay of recruitmentModifiable risk factorsRegional Referral HospitalSGA neonatesVaginal delivery