Sex Differences in Gene Expression and Regulatory Networks across 29 Human Tissues
Lopes-Ramos C, Chen C, Kuijjer M, Paulson J, Sonawane A, Fagny M, Platig J, Glass K, Quackenbush J, DeMeo D. Sex Differences in Gene Expression and Regulatory Networks across 29 Human Tissues. Cell Reports 2020, 31: 107795. PMID: 32579922, PMCID: PMC7898458, DOI: 10.1016/j.celrep.2020.107795.Peer-Reviewed Original ResearchConceptsGene regulatory networksTranscription factorsGenotype-Tissue ExpressionRegulatory networksArchitecture of gene regulatory networksRepertoire of transcription factorsSets of transcription factorsRegulatory network structureWhole-genome expression profilingTissue-related functionsGenes associated with Parkinson's diseaseHuman healthy tissuesGene regulationGene expressionMolecular basisSystems-based analysisExpression profilesGenesAlzheimer's diseaseRegulatory processesHuman tissuesExpressionTranscriptionTissueSex differences