Smooth quantile normalization
Hicks S, Okrah K, Paulson J, Quackenbush J, Irizarry R, Bravo H. Smooth quantile normalization. Biostatistics 2017, 19: 185-198. PMID: 29036413, PMCID: PMC5862355, DOI: 10.1093/biostatistics/kxx028.Peer-Reviewed Original ResearchConceptsMonte Carlo simulation studyGlobal normalization methodsQuantile normalizationBias-variance tradeoffSimulation studyHigh-throughput datasetsSequencing read countsHigh-throughput dataGenomic data analysisSmooth quantile normalizationTechnical variationBetween-sample normalizationBiological conditionsGlobal propertiesStatistical distributionBiological groupsNormalizationReducing other formsGlobal differences