2024
Self-injurious unnatural death among Veterans with HIV
Smith A, Goulet J, Vlahov D, Justice A, Womack J. Self-injurious unnatural death among Veterans with HIV. AIDS 2024, 38: 1570-1578. PMID: 38814683, DOI: 10.1097/qad.0000000000003940.Peer-Reviewed Original ResearchVeterans Aging Cohort StudyNested case-control studyModifiable risk factorsRisk of suicideCase-control studyRisk factorsIdentification of modifiable risk factorsCategorization of deathsIncidence density samplingAging Cohort StudyCohort of veteransIncreased risk of suicideConditional logistic regressionHigher pain levelsUse disorderPublic health burdenDrug use disordersUnnatural deathsDeath codesUnintentional causesInternational ClassificationHIV statusExcess deathsPrevention effortsAlcohol use disorder
2023
Risk factors for suicide among veterans living with and without HIV: a nested case-control study
Smith A, Goulet J, Vlahov D, Justice A, Womack J. Risk factors for suicide among veterans living with and without HIV: a nested case-control study. AIDS And Behavior 2023, 28: 115-124. PMID: 37751112, PMCID: PMC11289766, DOI: 10.1007/s10461-023-04164-3.Peer-Reviewed Original ResearchHIV-specific risk factorsVeterans Aging Cohort StudyCase-control studyRisk factorsRisk of suicideAging Cohort StudyDiagnosis of HIVMost risk factorsUse of benzodiazepinesConditional logistic regressionMental health treatmentSubstance use disordersPrevious suicide attemptsCohort studyHIV statusRates of suicideHigh prevalenceGeneral populationUse disordersHealth treatmentAffective disordersHIVSuicide attemptsLogistic regressionPWH
2020
Are we missing opioid-related deaths among people with HIV?
Becker WC, Gordon KS, Edelman EJ, Goulet JL, Kerns RD, Marshall BDL, Fiellin DA, Justice AC, Tate JP. Are we missing opioid-related deaths among people with HIV? Drug And Alcohol Dependence 2020, 212: 108003. PMID: 32417360, PMCID: PMC9580216, DOI: 10.1016/j.drugalcdep.2020.108003.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyOpioid useOverdose deathsLife-limiting conditionsUnnatural deathsGreater oddsAging Cohort StudyVACS IndexOpioid exposureCohort studyHIV infectionHIV statusRisk factorsOdds ratioDeath filesIndex causeHIVDisease severityDeathDecedentsIllicit useDifferential misclassificationOddsCauseOpioids
2016
The Effect of Substance Use Disorders on the Association Between Guideline-concordant Long-term Opioid Therapy and All-cause Mortality
Gaither JR, Goulet JL, Becker WC, Crystal S, Edelman EJ, Gordon K, Kerns RD, Rimland D, Skanderson M, Justice AC, Fiellin DA. The Effect of Substance Use Disorders on the Association Between Guideline-concordant Long-term Opioid Therapy and All-cause Mortality. Journal Of Addiction Medicine 2016, 10: 418-428. PMID: 27610580, PMCID: PMC5083184, DOI: 10.1097/adm.0000000000000255.Peer-Reviewed Original ResearchConceptsSubstance use disordersLong-term opioid therapyCause mortalityOpioid therapySUD treatmentUse disordersLower mortalityTime-updated Cox regressionUntreated substance use disordersVeterans Aging Cohort StudyOpioid-prescribing guidelinesGuideline-concordant careSUD statusAging Cohort StudyClinical practice guidelinesSUD treatment servicesOverall sampleHIV patientsCohort studyCox regressionPractice guidelinesPatientsTreatment servicesHigh mortalityMortalityMinority Men Who Have Sex with Men Demonstrate Increased Risk for HIV Transmission
Gordon KS, Edelman EJ, Justice AC, Fiellin DA, Akgün K, Crystal S, Duggal M, Goulet JL, Rimland D, Bryant KJ. Minority Men Who Have Sex with Men Demonstrate Increased Risk for HIV Transmission. AIDS And Behavior 2016, 21: 1497-1510. PMID: 27771818, PMCID: PMC5380471, DOI: 10.1007/s10461-016-1590-8.Peer-Reviewed Original ResearchConceptsDetectable HIV-1 RNAHIV-1 RNAHIV transmissionOdds ratioMSM groupVeterans Aging Cohort StudyMinority MSMAging Cohort StudyMultiple sexual partnersMultiple sex partnersNon-condom useCohort studyInfluence of drugsComparator groupRisk factorsHispanic MSMWhite MSMLow prevalenceHigh incidenceSex partnersSexual partnersMSMSexMinority menGroupContemplation of Smoking Cessation and Quit Attempts in Human Immunodeficiency Virus–Infected and Uninfected Veterans
Shahrir S, Tindle HA, McGinnis KA, Fiellin DA, Goulet J, Akgün KM, Gibert CL, Rodriguez-Barradas MC, Crothers K. Contemplation of Smoking Cessation and Quit Attempts in Human Immunodeficiency Virus–Infected and Uninfected Veterans. Substance Abuse 2016, 37: 315-322. PMID: 26167725, DOI: 10.1080/08897077.2015.1062458.Peer-Reviewed Original ResearchConceptsUnhealthy alcohol useVeterans Aging Cohort StudyHuman immunodeficiency virusSmoking cessationQuit attemptsPulmonary disease diagnosisPrior quit attemptsAlcohol useImmunodeficiency virusKey modifiable risk factorsStratified multivariable analysesSustained smoking cessationModifiable risk factorsAging Cohort StudyStudy of HIVUninfected smokersUninfected veteransUninfected patientsCohort studyCessation ratesHIV statusMultivariable analysisRisk factorsOdds ratioTargeting HIV
2015
Food Insecurity and Health: Data from the Veterans Aging Cohort Study
Wang EA, McGinnis KA, Goulet J, Bryant K, Gibert C, Leaf DA, Mattocks K, Fiellin LE, Vogenthaler N, Justice AC, Fiellin DA. Food Insecurity and Health: Data from the Veterans Aging Cohort Study. Public Health Reports 2015, 130: 261-268. PMID: 25931630, PMCID: PMC4388224, DOI: 10.1177/003335491513000313.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyVeterans Health AdministrationAging Cohort StudyCohort studyWorse controlMedical conditionsControl of hypertensionIndependent risk factorMultivariable logistic regressionTest of trendFood insecureFood insecurityRisk factorsHealth AdministrationPast monthLogistic regressionRecent homelessnessHealth careHypertensionVeteransHIVDepressionAfrican AmericansMarijuana usePrevalenceTHE ASSOCIATION BETWEEN HIV STATUS AND HOMELESSNESS AMONG VETERANS IN CARE
Ghose T, Gordon A, Metraux S, Mattocks K, Goulet J, Rodriguez‐Barradas M, Day N, Blackstock O, Justice A. THE ASSOCIATION BETWEEN HIV STATUS AND HOMELESSNESS AMONG VETERANS IN CARE. Journal Of Community Psychology 2015, 43: 189-198. DOI: 10.1002/jcop.21673.Peer-Reviewed Original ResearchVeterans Affairs Health Care SystemVeterans Aging Cohort StudyHIV-negative veteransSubstance useAging Cohort StudyAfrican American substance usersGeneral veteran populationHIV-positive statusHazardous alcohol useHealth care systemCohort studyHIV infectionHIV-positiveHIV statusHigh riskVeteran populationWomen veteransHIVAlcohol useCare systemSubstance usersHomelessness riskLast monthVeteransHomelessness prevalence
2014
Relationship Between Alcohol Use Categories and Noninvasive Markers of Advanced Hepatic Fibrosis in HIV-Infected, Chronic Hepatitis C Virus–Infected, and Uninfected Patients
Lim JK, Tate JP, Fultz SL, Goulet JL, Conigliaro J, Bryant KJ, Gordon AJ, Gibert C, Rimland D, Goetz MB, Klein MB, Fiellin DA, Justice AC, Re V. Relationship Between Alcohol Use Categories and Noninvasive Markers of Advanced Hepatic Fibrosis in HIV-Infected, Chronic Hepatitis C Virus–Infected, and Uninfected Patients. Clinical Infectious Diseases 2014, 58: 1449-1458. PMID: 24569533, PMCID: PMC4001286, DOI: 10.1093/cid/ciu097.Peer-Reviewed Original ResearchConceptsChronic hepatitis C virusAdvanced hepatic fibrosisHuman immunodeficiency virusHepatitis C virusAlcohol use categoriesAlcohol-related diagnosesHIV/HCV-coinfected patientsHepatic fibrosisAlcohol consumptionNonhazardous drinkingBinge drinkingHIV/HCV groupAlcohol Use Disorders Identification Test-Consumption (AUDIT-C) questionnaireVeterans Aging Cohort StudyFIB-4 indexAging Cohort StudyCross-sectional studyHCV groupHCV statusHIV-InfectedUninfected participantsChronic hepatitisUninfected patientsCohort studyLiver disease
2012
Receipt of Opioid Analgesics by HIV-Infected and Uninfected Patients
Edelman EJ, Gordon K, Becker WC, Goulet JL, Skanderson M, Gaither JR, Brennan Braden J, Gordon AJ, Kerns RD, Justice AC, Fiellin DA. Receipt of Opioid Analgesics by HIV-Infected and Uninfected Patients. Journal Of General Internal Medicine 2012, 28: 82-90. PMID: 22895747, PMCID: PMC3539026, DOI: 10.1007/s11606-012-2189-z.Peer-Reviewed Original ResearchConceptsLong-term opioidsHigh-dose opioidsUninfected patientsOpioid receiptHIV statusPain diagnosisHIV infectionVeterans Aging Cohort StudyVeterans Health Administration (VHA) careDaily morphine equivalent doseAcute pain diagnosisDays of opioidsMorphine equivalent doseAging Cohort StudyDesignCross-sectional analysisChronic pain diagnosesICD-9 codesVulnerable patient populationAverage daily doseMorphine equivalentsOpioid prescriptionsCohort studyDaily doseOpioid analgesicsPain management
2011
Food Insecurity is Associated with Poor Virologic Response among HIV-Infected Patients Receiving Antiretroviral Medications
Wang EA, McGinnis KA, Fiellin DA, Goulet JL, Bryant K, Gibert CL, Leaf DA, Mattocks K, Sullivan LE, Vogenthaler N, Justice AC, for the VACS Project Team. Food Insecurity is Associated with Poor Virologic Response among HIV-Infected Patients Receiving Antiretroviral Medications. Journal Of General Internal Medicine 2011, 26: 1012-1018. PMID: 21573882, PMCID: PMC3157515, DOI: 10.1007/s11606-011-1723-8.Peer-Reviewed Original ResearchConceptsHIV-1 RNAHIV disease outcomeLow CD4 countAntiretroviral medicationsBody mass indexCD4 countMass indexDisease outcomeVeterans Aging Cohort StudyPoor virologic responseUnsuppressed viral loadAging Cohort StudyMultivariable logistic regressionAntiretroviral medication adherenceCross-sectional studyFood insecure participantsFood-secure participantsPotential causal associationVirologic responseVirologic suppressionCohort studyHIV diseaseHIV outcomesAdjusted analysisFood insecurityNonmedical use of prescription opioids and pain in veterans with and without HIV
Barry DT, Goulet JL, Kerns RK, Becker WC, Gordon AJ, Justice AC, Fiellin DA. Nonmedical use of prescription opioids and pain in veterans with and without HIV. Pain 2011, 152: 1133-1138. PMID: 21354703, PMCID: PMC3086805, DOI: 10.1016/j.pain.2011.01.038.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnalgesics, OpioidChi-Square DistributionCohort StudiesFemaleHealth SurveysHIV InfectionsHumansLogistic ModelsMaleMental DisordersMiddle AgedOdds RatioOpioid-Related DisordersPainPain MeasurementPrescriptionsPsychiatric Status Rating ScalesRetrospective StudiesSelf ReportSurveys and QuestionnairesVeterans HealthYoung AdultConceptsHuman immunodeficiency virusPrescription opioidsComponent summaryHIV statusPain interferenceUse disordersForm Health Survey Mental Component SummarySF-12 Physical Component SummaryVeterans Aging Cohort StudyNonmedical usePharmacy record dataAlcohol Use Disorders Identification Test (AUDIT) scoresAging Cohort StudyPhysical component summaryMental component summaryOpioid use disorderMedian participant ageDrug use disordersLegitimate medical reasonsPast-month cigarette useChi-squared testU.S. military veteransHepatitis COpioid prescriptionsCohort studyAlcohol consumption and depressive symptoms over time: A longitudinal study of patients with and without HIV infection
Sullivan LE, Goulet JL, Justice AC, Fiellin DA. Alcohol consumption and depressive symptoms over time: A longitudinal study of patients with and without HIV infection. Drug And Alcohol Dependence 2011, 117: 158-163. PMID: 21345624, PMCID: PMC3113463, DOI: 10.1016/j.drugalcdep.2011.01.014.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyNon-hazardous drinkersDepressive symptomsAlcohol consumptionAlcohol abuseCohort studyHIV infectionBinge drinkersBinge drinkingNon-hazardous drinkingAging Cohort StudyPatient Health QuestionnaireUnhealthy alcohol consumptionCurrent alcohol useHIV statusHealth QuestionnaireTime-varying outcomeHazardous drinkersPatientsHIVHazardous drinkingAlcohol dependenceSymptomsAlcohol useSimilar alterationsAssociation of Age and Comorbidity with Physical Function in HIV-Infected and Uninfected Patients: Results from the Veterans Aging Cohort Study
Oursler KK, Goulet JL, Crystal S, Justice AC, Crothers K, Butt AA, Rodriguez-Barradas MC, Favors K, Leaf D, Katzel LI, Sorkin JD. Association of Age and Comorbidity with Physical Function in HIV-Infected and Uninfected Patients: Results from the Veterans Aging Cohort Study. AIDS Patient Care And STDs 2011, 25: 13-20. PMID: 21214375, PMCID: PMC3030913, DOI: 10.1089/apc.2010.0242.Peer-Reviewed Original ResearchConceptsChronic pulmonary diseaseAge-associated comorbiditiesPhysical functionUninfected patientsPulmonary diseaseUninfected subjectsSelf-reported physical functionVeterans Aging Cohort StudyAging of HIVHIV care guidelinesVeterans Aging CohortHIV clinical careAging Cohort StudyAssociation of ageCross-sectional analysisOlder HIVCohort studyHIV infectionHIV statusCare guidelinesPoor functionCardiovascular diseaseClinical carePhysical subscaleHIV
2010
Patterns of drug use and abuse among aging adults with and without HIV: A latent class analysis of a US Veteran cohort
Green TC, Kershaw T, Lin H, Heimer R, Goulet JL, Kraemer KL, Gordon AJ, Maisto SA, Day NL, Bryant K, Fiellin DA, Justice AC. Patterns of drug use and abuse among aging adults with and without HIV: A latent class analysis of a US Veteran cohort. Drug And Alcohol Dependence 2010, 110: 208-220. PMID: 20395074, PMCID: PMC3087206, DOI: 10.1016/j.drugalcdep.2010.02.020.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyHIV statusMultidrug usersDrug useLatent class analysisUS Veteran cohortAging Cohort StudyActive drug useSelf-reported drug useMental health disordersProblem of obesityElectronic medical recordsUninfected veteransCohort studyClinical variablesDrug use consequencesSocio-demographic covariatesMedical recordsHigh prevalenceUninfected adultsAge 50HIVHealth disordersDrug usersVeteran cohort
2008
Depression Symptoms and Treatment Among HIV Infected and Uninfected Veterans
Sueoka K, Goulet JL, Fiellin DA, Rimland D, Butt AA, Gibert C, Rodriguez-Barradas MC, Bryant K, Crystal S, Justice AC. Depression Symptoms and Treatment Among HIV Infected and Uninfected Veterans. AIDS And Behavior 2008, 14: 272-279. PMID: 18648927, PMCID: PMC3125603, DOI: 10.1007/s10461-008-9428-7.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudySelective serotonin reuptake inhibitorsDepressive symptomsMental health providersDepression treatmentHealth providersPatient Health Questionnaire scoresActive depressive symptomsAging Cohort StudySerotonin reuptake inhibitorsCommon comorbid conditionsNon-Hispanic whitesHIV providersUninfected subjectsUninfected veteransCohort studyProspective cohortReuptake inhibitorsComorbid conditionsHIV statusPrimary careMental health counselingMultivariable modelQuestionnaire scoresDepression symptomsQuantifying the Decrement in Utility from Perceived Side Effects of Combination Antiretroviral Therapies in Patients with HIV
Braithwaite RS, Goulet J, Kudel I, Tsevat J, Justice AC. Quantifying the Decrement in Utility from Perceived Side Effects of Combination Antiretroviral Therapies in Patients with HIV. Value In Health 2008, 11: 975-979. PMID: 18225989, PMCID: PMC3121315, DOI: 10.1111/j.1524-4733.2007.00315.x.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyBothersome symptomsSF-6D utilitiesAntiretroviral therapyCD4 countSide effectsVeterans Aging Cohort StudyAging Cohort StudySF-12 scoresAfrican American raceHazardous alcohol consumptionQuality of lifeRecent drug useCART initiationMild anginaCohort studyMultivariable analysisCigarette smokingUnivariate analysisAmerican raceAlcohol consumptionDrug useUtility decrementsPatientsClinical decision
2006
Association of Comorbidity with Physical Disability in Older HIV-Infected Adults
Oursler KK, Goulet JL, Leaf DA, Akingicil A, Katzel LI, Justice A, Crystal S. Association of Comorbidity with Physical Disability in Older HIV-Infected Adults. AIDS Patient Care And STDs 2006, 20: 782-791. PMID: 17134352, DOI: 10.1089/apc.2006.20.782.Peer-Reviewed Original ResearchConceptsHIV-negative patientsPhysical functioningComorbid conditionsVeterans Aging Cohort StudyGeneral medical comorbidityHIV medical careHIV-negative veteransRelationship of comorbiditiesHIV disease stageHIV-negative subjectsAssociation of comorbiditiesChronic lung diseaseAging Cohort StudyCoronary artery diseaseYears of ageSelf-reported difficultyOlder HIVAntiretroviral therapyMedical comorbiditiesCohort studyArtery diseaseClinical factorsPatient groupDisease stageLung diseaseVeterans Aging Cohort Study (VACS)
Justice AC, Dombrowski E, Conigliaro J, Fultz SL, Gibson D, Madenwald T, Goulet J, Simberkoff M, Butt AA, Rimland D, Rodriguez-Barradas MC, Gibert CL, Oursler KA, Brown S, Leaf DA, Goetz MB, Bryant K. Veterans Aging Cohort Study (VACS). Medical Care 2006, 44: s13-s24. PMID: 16849964, PMCID: PMC3049942, DOI: 10.1097/01.mlr.0000223741.02074.66.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyHuman immunodeficiency virusAging Cohort StudyCohort studyHIV infectionGeneral medical clinicMultisite observational studyElectronic medical record systemRace/ethnicityUninfected patientsBaseline characteristicsMedical record systemTarget enrollmentImmunodeficiency virusObservational studyNational VAMedical clinicsInfectious diseasesDisease controlTelephone interviewsStudy designAlcohol useEnrollment targetsCareVeterans