2023
Subject and Family Perspectives from the Central Thalamic Deep Brain Stimulation Trial for Traumatic Brain Injury: Part II.
Fins J, Wright M, Shulman K, Henderson J, Schiff N. Subject and Family Perspectives from the Central Thalamic Deep Brain Stimulation Trial for Traumatic Brain Injury: Part II. Cambridge Quarterly Of Healthcare Ethics 2023, 1-24. PMID: 37850455, DOI: 10.1017/s0963180123000518.Peer-Reviewed Original ResearchFamily perspectiveTraumatic brain injuryOn-going careTrail-Making-TestDecision-making capacitySevere traumatic brain injuryBrain injurySupportive counselingStimulation trialsNarrative responsesPost-trial accessVoluntary informed consentPost-operative interviewsFamily membersSocial reintegrationMarkers of executive functionCognitive functionFamily dynamicsInformed consentPart BDeep brain stimulation trialsInterviewsExecutive functionDevice trialsTrials
2022
Subject and Family Perspectives from the Central Thalamic Deep Brain Stimulation for Traumatic Brain Injury Study: Part I
Fins J, Wright M, Henderson J, Schiff N. Subject and Family Perspectives from the Central Thalamic Deep Brain Stimulation for Traumatic Brain Injury Study: Part I. Cambridge Quarterly Of Healthcare Ethics 2022, 31: 419-443. PMID: 36398511, DOI: 10.1017/s0963180122000226.Peer-Reviewed Original ResearchConceptsCentral thalamic deep brain stimulationVoluntary informed consentTraumatic brain injuryDecision-making authorityBrain injuryDeep brain stimulationTherapeutic misconceptionCognitive restorationBrain stimulationAgency of subjectsInformed consentSevere traumatic brain injuryTraumatic brain injury studiesThalamic deep brain stimulationConsentTreatment of traumatic brain injuryEnrollment decisionsBrain injury studiesFamily perspectiveInterpersonal interactionsDecisionCognitive disabilitiesStudy enrollmentReturn to workSocial structure
2018
Assessment of Covert Consciousness in the Intensive Care Unit
Edlow B, Fins J. Assessment of Covert Consciousness in the Intensive Care Unit. Journal Of Head Trauma Rehabilitation 2018, 33: 424-434. PMID: 30395042, PMCID: PMC6317885, DOI: 10.1097/htr.0000000000000448.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingTraumatic brain injuryAcute severe traumatic brain injurySevere traumatic brain injuryIntensive care unitCovert consciousnessEthical challengesIntensive care unit patientsTask-based functional magnetic resonance imagingTask-based fMRILife-sustaining therapyWithdrawal of life-sustaining therapyCare unitEthical frameworkBehavioral assessmentCritically ill patientsEvaluation normsMagnetic resonance imagingConsciousnessBrain injuryGoals of careClinical scenariosIll patientsRecovered consciousnessTreatment decisions
2012
Central Thalamic Deep Brain Stimulation to Promote Recovery from Chronic Posttraumatic Minimally Conscious State: Challenges and Opportunities
Giacino J, Fins J, Machado A, Schiff N. Central Thalamic Deep Brain Stimulation to Promote Recovery from Chronic Posttraumatic Minimally Conscious State: Challenges and Opportunities. Neuromodulation Technology At The Neural Interface 2012, 15: 339-349. PMID: 22624587, DOI: 10.1111/j.1525-1403.2012.00458.x.Peer-Reviewed Original ResearchMeSH KeywordsBrain InjuriesBrain MappingClinical Trials as TopicDeep Brain StimulationElectrodes, ImplantedHumansInformed ConsentMonitoring, IntraoperativeNeuronavigationNeurosurgical ProceduresPatient Care PlanningPatient SelectionPersistent Vegetative StatePostoperative CareRecovery of FunctionThalamusConceptsTraumatic brain injuryCentral thalamic deep brain stimulationCT-DBSMinimally conscious stateThalamic deep brain stimulationOutcome measuresDeep brain stimulationSecondary outcome measuresIncreased functional communicationChronic minimally conscious stateBrain stimulationComa Recovery Scale-RevisedSingle-subject studySevere traumatic brain injuryImproved behavioral functionFunctional independenceObject namingWorking memoryConscious stateSustained attentionScale-RevisedBehavioral functionsFunctional communicationModulate arousalCentral thalamus