Prolonged Unconsciousness is Common in COVID‐19 and Associated with Hypoxemia
Waldrop G, Safavynia S, Barra M, Agarwal S, Berlin D, Boehme A, Brodie D, Choi J, Doyle K, Fins J, Ganglberger W, Hoffman K, Mittel A, Roh D, Mukerji S, Der Nigoghossian C, Park S, Schenck E, Salazar‐Schicchi J, Shen Q, Sholle E, Velazquez A, Walline M, Westover M, Brown E, Victor J, Edlow B, Schiff N, Claassen J. Prolonged Unconsciousness is Common in COVID‐19 and Associated with Hypoxemia. Annals Of Neurology 2022, 91: 740-755. PMID: 35254675, PMCID: PMC9082460, DOI: 10.1002/ana.26342.Peer-Reviewed Original ResearchConceptsCessation of mechanical ventilationAssociated with hypoxemiaMedian timeMechanical ventilationAssociated with more severe hypoxemiaDays of hypoxemiaEvidence of structural brain injurySevere coronavirus disease 2019Cox proportional hazards modelsArterial partial pressure of oxygenImpairment of consciousnessSevere COVID-19Survivors of severe COVID-19Proportional hazards modelArterial partial pressureBrain injuryStructural brain injurySevere hypoxemiaCohort studyLife-sustaining therapyEndotracheal intubationHypoxemiaProlonged unconsciousnessPartial pressure of oxygenPatients