2023
Thalamic deep brain stimulation in traumatic brain injury: a phase 1, randomized feasibility study
Schiff N, Giacino J, Butson C, Choi E, Baker J, O’Sullivan K, Janson A, Bergin M, Bronte-Stewart H, Chua J, DeGeorge L, Dikmen S, Fogarty A, Gerber L, Krel M, Maldonado J, Radovan M, Shah S, Su J, Temkin N, Tourdias T, Victor J, Waters A, Kolakowsky-Hayner S, Fins J, Machado A, Rutt B, Henderson J. Thalamic deep brain stimulation in traumatic brain injury: a phase 1, randomized feasibility study. Nature Medicine 2023, 29: 3162-3174. PMID: 38049620, PMCID: PMC11087147, DOI: 10.1038/s41591-023-02638-4.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryDeep brain stimulationExecutive controlProcessing speedBrain stimulationImprove executive controlCentral lateral (CL) nucleusTrail-Making TestChronic phase of recoveryBrain injuryYears post-injuryFrontostriatal networkEfficacy of deep brain stimulationExecutive functionConverging evidenceLimit quality of lifeEfficacy measuresMsTBIPhase of recoveryPost-injuryRandomized feasibility studyThalamic deep brain stimulationQuality of lifeParticipantsProtocol non-compliance
2012
Improving end-of-life care for head and neck cancer patients
Shuman A, Fins J, Prince M. Improving end-of-life care for head and neck cancer patients. Expert Review Of Anticancer Therapy 2012, 12: 335-343. PMID: 22369325, DOI: 10.1586/era.12.6.Peer-Reviewed Original ResearchConceptsEnd-of-life experiencesHead and neck cancer patientsEnd-of-lifeNeck cancer patientsImprove end-of-life careEnd-of-life carePalliative care team involvementTerminal head and neck cancer patientsHead and neck cancerCancer patientsQuality of lifeNeck cancerClinical decision-makingPractice improvementTeam involvementSymptom controlEthical challengesPatient populationTreatment of head and neck cancerRelevant dataDecision-makingPatientsCancerCareProactive consideration
2004
Screening and Cognitive Impairment: Ethics of Forgoing Mammography in Older Women
Raik B, Miller F, Fins J. Screening and Cognitive Impairment: Ethics of Forgoing Mammography in Older Women. Journal Of The American Geriatrics Society 2004, 52: 440-444. PMID: 14962162, DOI: 10.1111/j.1532-5415.2004.52119.x.Peer-Reviewed Original ResearchConceptsCognitively impaired womenCognitive impairmentQuality of lifeDecision-making capacityScreening interventionsMammographic screeningEarly cognitive impairmentLonger life expectancyPatient's capacityVulnerable populationsImpaired womenLife expectancyRisk of undertreatmentMammographyBreast cancerWomenEthical questionsDecision-making processPotential benefitsRiskScreeningRisk/benefit analysisImpairmentOlderDementia