2022
Cognitive-Motor Dissociation Following Pediatric Brain Injury
Kim N, O'Sullivan J, Olafson E, Caliendo E, Nowak S, Voss H, Lowder R, Watson W, Ivanidze J, Fins J, Schiff N, Hill N, Shah S. Cognitive-Motor Dissociation Following Pediatric Brain Injury. Neurology Clinical Practice 2022, 12: 248-257. PMID: 35733619, PMCID: PMC9208423, DOI: 10.1212/cpj.0000000000001169.Peer-Reviewed Original ResearchCognitive-motor dissociationCognitive functionParticipants' EEGSemantic processing of wordsCovert cognitionBrain injuryProcessing of wordsIntact semantic processingIdentifying such personsResponses to auditory stimuliDiverse batteryCognitive abilitiesMinimally conscious stateCognitive-motorCognitive capacityPediatric brain injuryCommunication attemptsAuditory stimuliAged 9CognitionNeuroimagingMotor outputConscious stateParticipantsBrainEthics Priorities of the Curing Coma Campaign: An Empirical Survey
Lewis A, Claassen J, Illes J, Jox R, Kirschen M, Rohaut B, Trevick S, Young M, Fins J. Ethics Priorities of the Curing Coma Campaign: An Empirical Survey. Neurocritical Care 2022, 37: 12-21. PMID: 35505222, PMCID: PMC10034145, DOI: 10.1007/s12028-022-01506-2.Peer-Reviewed Original ResearchConceptsCountry of practiceClinical careEthical prioritiesClinical researchTranslation of researchDisclosure of resultsMethodsAn electronic surveyEthics Working GroupMedical futilityElectronic surveyResultsThe surveyDiagnostic definitionCareUnited StatesEthical topicsEmpirical surveyMinimally conscious stateEthicsCuring Coma CampaignGlobal initiativesConclusionsCollaborationRespondentsPrognostication of patientsWorking GroupSurveyDisorders of Consciousness, Disability Rights, and Triage During the Covid-19 Pandemic
Fins J. Disorders of Consciousness, Disability Rights, and Triage During the Covid-19 Pandemic. 2022, 191-202. DOI: 10.4324/9781003289487-25.Peer-Reviewed Original ResearchPersonalized medicine and disorders of consciousness
Fins J. Personalized medicine and disorders of consciousness. 2022, 131-140. DOI: 10.1093/oso/9780198863465.003.0010.Peer-Reviewed Original ResearchPersonalized medicineNext-generation personalized medicineDisorders of consciousnessDevelopment of therapeuticsDomain of personalized medicineAccurate diagnostic classificationPathological phenotypesUnique biologyTherapeutic responseMolecular levelIndividual diseasesGuiding treatmentCare of patientsPersonalized therapySide effectsTherapeutic effectMinimally conscious stateBiological characteristicsMolecular biomarkersBiologyDiseaseCharacterize diseaseNeural circuitryPatientsDiagnostic classification
2021
The neuroethics of disorders of consciousness: a brief history of evolving ideas
Young M, Bodien Y, Giacino J, Fins J, Truog R, Hochberg L, Edlow B. The neuroethics of disorders of consciousness: a brief history of evolving ideas. Brain 2021, 144: 3291-3310. PMID: 34347037, PMCID: PMC8883802, DOI: 10.1093/brain/awab290.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessMulti-Society Task ForceAmerican Congress of Rehabilitation MedicineNational Institute on DisabilityNatural history of recoveryHistory of recoveryAmerican Academy of NeurologyRehabilitation researchRehabilitation medicineTreatment of disorders of consciousnessResponsive careClinical careTaxonomy of disorders of consciousnessAmerican CongressVulnerable populationsIndependent livingProlonged disordersMinimally conscious stateTask ForceAmerican AcademyIncreased awarenessDisability rights perspectiveCareCritically ill patientsBiomedical ethics
2020
Disorders of Consciousness and Disability Law
Fins J, Wright M, Bagenstos S. Disorders of Consciousness and Disability Law. Mayo Clinic Proceedings 2020, 95: 1732-1739. PMID: 32753147, DOI: 10.1016/j.mayocp.2020.02.008.Peer-Reviewed Original ResearchConceptsAmerican Congress of Rehabilitation MedicineNational Institute on DisabilityMulti-Society Task Force ReportMinimally conscious stateUndertreatment of painDisorders of consciousnessRehabilitation of patientsSystematic evidence-based reviewDisability lawAmerican Academy of NeurologyChronic careEvidence-based reviewRehabilitation researchInadequate rehabilitationRehabilitation medicineMedical careNational guidelinesTask Force ReportAmerican CongressNew England JournalPractice guidelinesMedical mainstreamIndependent livingCareInternational disability law
2019
Disorders of Consciousness, Past, Present, and Future
Fins J. Disorders of Consciousness, Past, Present, and Future. Cambridge Quarterly Of Healthcare Ethics 2019, 28: 603-615. PMID: 31405394, DOI: 10.1017/s0963180119000719.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessLegal obligationsPersistent vegetative stateConsciousness literatureNational Institute on DisabilityCognitive motor dissociationMinimally conscious stateCounter-narrativesAmerican Academy of NeurologyVegetative stateMotor dissociationCovert consciousnessObligationsConscious stateDisordersIndependent livingStateDisorders of Consciousness in Clinical Practice
Fins J. Disorders of Consciousness in Clinical Practice. 2019, 449-478. DOI: 10.1093/med/9780190208875.003.0011.Peer-Reviewed Original ResearchEnd-of-life careEnd-of-lifeLong-term careImpaired decision-making capacityDisorders of consciousnessClinical practiceDecision-making capacityAncillary care obligationsVulnerable populationsProfessional obligationsCareMinimally conscious stateNeuroimaging assessmentsIntensive careCare obligationsDiagnostic classificationBrain injuryCommunication strategiesCovert consciousnessClinicInitial presentationConscious stateEthical implicationsPatientsRehabilitationOnce and Future Clinical Neuroethics: A History of What Was and What Might Be.
Fins J. Once and Future Clinical Neuroethics: A History of What Was and What Might Be. The Journal Of Clinical Ethics 2019, 30: 27-34. PMID: 30896441, DOI: 10.1086/jce2019301027.Peer-Reviewed Original Research
2016
Neuroethics and Disorders of Consciousness: Discerning Brain States in Clinical Practice and Research
Fins J. Neuroethics and Disorders of Consciousness: Discerning Brain States in Clinical Practice and Research. The AMA Journal Of Ethic 2016, 18: 1182. PMID: 28009244, DOI: 10.1001/journalofethics.2016.18.12.ecas2-1612.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessMinimally conscious stateEnd-of-life careConscious stateEnd-of-lifeEthical obligationNeuropalliative careDeep brain stimulationPatientsBrain statesClinicians' ethical obligationsClinical practiceCivil rightsConsciousnessScientific advancesDiagnostic discernmentClinical researchBrain stimulationResearch decisionsDisordersFunctional communicationInvestigate useCareNeuroethicsPainBrain death and disorders of consciousness
Schiff N, Fins J. Brain death and disorders of consciousness. Current Biology 2016, 26: r572-r576. PMID: 27404252, DOI: 10.1016/j.cub.2016.02.027.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessBrain-dead patientsBrain deathVegetative stateCognitive motor dissociationScientific knowledgeCognitive functionMinimally conscious stateNon-medical specialistsSocietal contextBrain statesConsciousnessConscious stateMotor dissociationBrainDisordersDead patientsConceptual frameworkLack of sustainabilityHigher levelsFutilityParadoxDistinctionWhither the “Improvement Standard”? Coverage for Severe Brain Injury after Jimmo v. Sebelius
Fins J, Wright M, Kraft C, Rogers A, Romani M, Godwin S, Ulrich M. Whither the “Improvement Standard”? Coverage for Severe Brain Injury after Jimmo v. Sebelius. The Journal Of Law, Medicine & Ethics 2016, 44: 182-193. PMID: 27256134, DOI: 10.1177/1073110516644209.Peer-Reviewed Original ResearchRehabilitation, Education, and the Integration of Individuals with Severe Brain Injury into Civil Society: Towards an Expanded Rights Agenda in Response to New Insights from Translational Neuroethics and Neuroscience.
Wright M, Fins J. Rehabilitation, Education, and the Integration of Individuals with Severe Brain Injury into Civil Society: Towards an Expanded Rights Agenda in Response to New Insights from Translational Neuroethics and Neuroscience. Yale Journal Of Health Policy, Law, And Ethics 2016, 16: 233-87. PMID: 29756752.Peer-Reviewed Original Research
2015
Rights Come to Mind
Fins J. Rights Come to Mind. 2015 DOI: 10.1017/cbo9781139051279.Peer-Reviewed Original ResearchNeuro-palliative care and disorders of consciousness
Fins J, Pohl B. Neuro-palliative care and disorders of consciousness. 2015, 285-291. DOI: 10.1093/med/9780199656097.003.0103.Peer-Reviewed Original ResearchPalliative care expertiseMinimally conscious stateBrain injuryPalliative carePalliative medicineCare expertiseCareDisorders of consciousnessConscious stateDefinition criteriaNihilistic attitudeInjuryPatientsDistressInterventionSurvivorsTherapeutic interventionsCliniciansDisordersNeuroprosthetic devicesSufferingMedicineAttitudes
2013
Disorders of Consciousness Following Severe Brain Injury
Fins J, Schiff N. Disorders of Consciousness Following Severe Brain Injury. 2013, 162-174. DOI: 10.1093/acprof:oso/9780195389784.003.0013.Peer-Reviewed Original ResearchDisorders of consciousnessBrain statesInterviews of familiesTraditional nosologyBehavioral measuresFunctional communicationMinimally conscious stateNeuroimaging dataDiagnostic classificationMeasures of assessmentBrain injuryDisordersConscious stateBrainFamily experiencesClinical practiceNeuroimagingNosology
2012
Central Thalamic Deep Brain Stimulation to Promote Recovery from Chronic Posttraumatic Minimally Conscious State: Challenges and Opportunities
Giacino J, Fins J, Machado A, Schiff N. Central Thalamic Deep Brain Stimulation to Promote Recovery from Chronic Posttraumatic Minimally Conscious State: Challenges and Opportunities. Neuromodulation Technology At The Neural Interface 2012, 15: 339-349. PMID: 22624587, DOI: 10.1111/j.1525-1403.2012.00458.x.Peer-Reviewed Original ResearchMeSH KeywordsBrain InjuriesBrain MappingClinical Trials as TopicDeep Brain StimulationElectrodes, ImplantedHumansInformed ConsentMonitoring, IntraoperativeNeuronavigationNeurosurgical ProceduresPatient Care PlanningPatient SelectionPersistent Vegetative StatePostoperative CareRecovery of FunctionThalamusConceptsTraumatic brain injuryCentral thalamic deep brain stimulationCT-DBSMinimally conscious stateThalamic deep brain stimulationOutcome measuresDeep brain stimulationSecondary outcome measuresIncreased functional communicationChronic minimally conscious stateBrain stimulationComa Recovery Scale-RevisedSingle-subject studySevere traumatic brain injuryImproved behavioral functionFunctional independenceObject namingWorking memoryConscious stateSustained attentionScale-RevisedBehavioral functionsFunctional communicationModulate arousalCentral thalamus
2011
Neuroethics, neuroimaging, and disorders of consciousness: promise or peril?
Fins J. Neuroethics, neuroimaging, and disorders of consciousness: promise or peril? Transactions Of The American Clinical And Climatological Association 2011, 122: 336-46. PMID: 21686236, PMCID: PMC3116331.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingDisorders of consciousnessPositron emission tomographyBehavior-based assessmentsMinimally conscious stateNeuroimaging dataNeuroimaging toolsBrain statesBrain injuryMagnetic resonance imagingNeuroimagingEmission tomographyConscious stateDisordersBrainResonance imagingNeuroimaging applicationsConsciousnessDiagnostic dilemmaTherapeutic useCommunication vectorNeuroethics
2010
Conflicts of interest in deep brain stimulation research and the ethics of transparency.
Fins J, Schiff N. Conflicts of interest in deep brain stimulation research and the ethics of transparency. The Journal Of Clinical Ethics 2010, 21: 125-32. PMID: 20866018, DOI: 10.1086/jce201021205.Peer-Reviewed Original Research
2009
Deep Brain Stimulation, Neuroethics, and the Minimally Conscious State: Moving Beyond Proof of Principle
Schiff N, Giacino J, Fins J. Deep Brain Stimulation, Neuroethics, and the Minimally Conscious State: Moving Beyond Proof of Principle. JAMA Neurology 2009, 66: 697-702. PMID: 19506129, DOI: 10.1001/archneurol.2009.79.Peer-Reviewed Original Research