2022
Proceedings of the Second Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness
Mainali S, Aiyagari V, Alexander S, Bodien Y, Boerwinkle V, Boly M, Brown E, Brown J, Claassen J, Edlow BL, Fink EL, Fins JJ, Foreman B, Frontera J, Geocadin RG, Giacino J, Gilmore EJ, Gosseries O, Hammond F, Helbok R, Claude Hemphill J, Hirsch K, Kim K, Laureys S, Lewis A, Ling G, Livesay SL, McCredie V, McNett M, Menon D, Molteni E, Olson D, O’Phelan K, Park S, Polizzotto L, Javier Provencio J, Puybasset L, Venkatasubba Rao CP, Robertson C, Rohaut B, Rubin M, Sharshar T, Shutter L, Sampaio Silva G, Smith W, Stevens RD, Thibaut A, Vespa P, Wagner AK, Ziai WC, Zink E, I Suarez J. Proceedings of the Second Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness. Neurocritical Care 2022, 37: 326-350. PMID: 35534661, PMCID: PMC9283342, DOI: 10.1007/s12028-022-01505-3.Peer-Reviewed Original Research
2020
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?
Wu H, Hariz M, Visser-Vandewalle V, Zrinzo L, Coenen V, Sheth S, Bervoets C, Naesström M, Blomstedt P, Coyne T, Hamani C, Slavin K, Krauss J, Kahl K, Taira T, Zhang C, Sun B, Toda H, Schlaepfer T, Chang J, Régis J, Schuurman R, Schulder M, Doshi P, Mosley P, Poologaindran A, Lázaro-Muñoz G, Pepper J, Schechtmann G, Fytagoridis A, Huys D, Gonçalves-Ferreira A, D’Haese P, Neimat J, Broggi G, Vilela-Filho O, Voges J, Alkhani A, Nakajima T, Richieri R, Djurfeldt D, Fontaine P, Martinez-Alvarez R, Okamura Y, Chandler J, Watanabe K, Barcia J, Reneses B, Lozano A, Gabriëls L, De Salles A, Halpern C, Matthews K, Fins J, Nuttin B. Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy? Molecular Psychiatry 2020, 26: 60-65. PMID: 33144712, PMCID: PMC7815503, DOI: 10.1038/s41380-020-00933-x.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderTreatment-refractory obsessive-compulsive disorderRefractory obsessive-compulsive disorderDeep brain stimulationTreatment of psychiatric patientsBrain stimulationProspective international multi-center studyY-BOCSClinical trialsAcceptable risk-benefit ratioPsychiatric patientsBrain areasPsychiatric indicationsRandomized controlled clinical trialLevel I evidenceRisk-benefit ratioClinical cohort studyMulti-center studyInternational multi-center studyLevel II evidenceRandomized controlled trialsSurgical treatmentPsychiatristsConsensus guidelinesCohort study
2011
Misuse Of The FDA’s Humanitarian Device Exemption In Deep Brain Stimulation For Obsessive-Compulsive Disorder
Fins J, Mayberg H, Nuttin B, Kubu C, Galert T, Sturm V, Stoppenbrink K, Merkel R, Schlaepfer T. Misuse Of The FDA’s Humanitarian Device Exemption In Deep Brain Stimulation For Obsessive-Compulsive Disorder. Health Affairs 2011, 30: 302-311. PMID: 21289352, DOI: 10.1377/hlthaff.2010.0157.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderHumanitarian Device ExemptionSevere obsessive-compulsive disorderUS Food and Drug AdministrationFDA humanitarian device exemptionNeuropsychiatric disordersFood and Drug AdministrationDeep brain stimulationClinical trialsBrain stimulationDrug AdministrationDisordersPatientsFederal regulationsPatient safeguardsProcedure—isExemption
2009
Chapter 9 Deep Brain Stimulation Ethical Issues in Clinical Practice and Neurosurgical Research
Fins J. Chapter 9 Deep Brain Stimulation Ethical Issues in Clinical Practice and Neurosurgical Research. 2009, 81-91. DOI: 10.1016/b978-0-12-374248-3.00010-0.Peer-Reviewed Original ResearchFood and Drug AdministrationFood and Drug Administration approvalDeep brain stimulationManagement of chronic painResearch of deep brain stimulationBenefit of neuromodulationTreatment of Parkinson's diseaseBrain stimulationRefractory Parkinson's diseaseChronic painParkinson's diseaseObsessive-compulsive disorderManagement of epilepsyClinical trialsClinical investigationDrug AdministrationEthical issuesPutative treatmentsClinical practiceTraumatic brain injuryClinical applicationMovement disordersEssential tremorTherapeutic deploymentPatients