Association of reduced CD4 T cell responses specific to varicella zoster virus with high incidence of herpes zoster in patients with systemic lupus erythematosus.
Park HB, Kim KC, Park JH, Kang TY, Lee HS, Kim TH, Jun JB, Bae SC, Yoo DH, Craft J, Jung S. Association of reduced CD4 T cell responses specific to varicella zoster virus with high incidence of herpes zoster in patients with systemic lupus erythematosus. The Journal Of Rheumatology 2004, 31: 2151-5. PMID: 15517626.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusVaricella-zoster virusCD4 T cell responsesT cell frequenciesT cell responsesCD4 T cellsHerpes zosterT cellsHigh incidenceLupus erythematosusZoster virusVZV-specific CD4 T cellsCell frequencyCD4 T-cell frequenciesCell responsesMemory T cellsFlow cytometry analysisVZV reactivationVZV stimulationDisease activityIL-10VZV antigenWhole blood samplesClinical statusRisk factors