2000
Roles of Fas and Fas ligand during mammary gland remodeling
Song J, Sapi E, Brown W, Nilsen J, Tartaro K, Kacinski B, Craft J, Naftolin F, Mor G. Roles of Fas and Fas ligand during mammary gland remodeling. Journal Of Clinical Investigation 2000, 106: 1209-1220. PMID: 11086022, PMCID: PMC381435, DOI: 10.1172/jci10411.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsApoptosisBlotting, WesternCaspase 3CaspasesCell LineCulture MediaCulture Media, Serum-FreeDexamethasoneEpithelial CellsFas Ligand ProteinFas ReceptorFemaleGene ExpressionHumansMammary Glands, AnimalMembrane GlycoproteinsMiceMice, Inbred BALB CMice, Inbred C3HMice, Inbred MRL lprMice, KnockoutPregnancyPregnancy, AnimalRNA, MessengerConceptsMammary epithelial cellsFas/FasL signalsMouse mammary epithelial cellsMammary gland remodelingFasL proteinApoptotic cellsEpithelial cellsInduction of apoptosisAccumulation of cellsSubsequent neoplastic developmentRole of FasMammary gland tissueFasL signalsMammary tissueCell deathExpression of FasFas-FasL interactionMouse mammary tissueMammary cellsCaspase-3Autocrine inductionFas ligandMammary epitheliumNeoplastic developmentTumor development
1998
Influence of antigen organization on the development of lupus autoantibodies
Fatenejad S, Bennett M, Moslehi J, Craft J. Influence of antigen organization on the development of lupus autoantibodies. Arthritis & Rheumatism 1998, 41: 603-612. PMID: 9550469, DOI: 10.1002/1529-0131(199804)41:4<603::aid-art7>3.0.co;2-e.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodiesAutoantibodiesAutoantigensGene ExpressionHeLa CellsHumansImmune ToleranceImmunizationLupus Erythematosus, SystemicMiceMice, Inbred C57BLMice, Inbred StrainsRecombinant Fusion ProteinsRecombinant ProteinsRibonucleoprotein, U1 Small NuclearRibonucleoproteins, Small NuclearRNA-Binding ProteinsT-LymphocytesTumor Cells, CulturedConceptsSystemic lupus erythematosusDevelopment of antibodiesH-2b backgroundDevelopment of lupusT cell responsesT cell toleranceAssessment of antibodiesNative snRNP particlesTypical immune responseLupus erythematosusAutoimmune responseNormal miceAntigen organizationImmune responseForeign immunogensH-2kCell toleranceMajor autoantigenCell responsesMiceRandom orderAntibodiesEukaryotic expression vectorLupusAutoantigens
1996
Propagation and regulation of systemic autoimmunity by gammadelta T cells.
Peng SL, Madaio MP, Hayday AC, Craft J. Propagation and regulation of systemic autoimmunity by gammadelta T cells. The Journal Of Immunology 1996, 157: 5689-98. PMID: 8955223, DOI: 10.4049/jimmunol.157.12.5689.Peer-Reviewed Original ResearchConceptsGammadelta T cellsAlphabeta T cellsT cellsRenal diseaseMurine lupusSystemic autoimmunityImmune complex renal diseaseT cell-intact miceRoles of alphabetaT-cell-deficient animalsLupus-prone miceSevere renal diseaseComplex renal diseaseLupus syndromeAutoantibody productionConventional CD4Polyclonal expansionPathogenic roleMiceHypergammaglobulinemiaDisease phenotypeAutoimmunityLupusDiseaseCells