2002
Detection of anti-elongation factor 2 kinase (calmodulin-dependent protein kinase III) antibodies in patients with systemic lupus erythematosus
Arora S, Yang JM, Craft J, Hait W. Detection of anti-elongation factor 2 kinase (calmodulin-dependent protein kinase III) antibodies in patients with systemic lupus erythematosus. Biochemical And Biophysical Research Communications 2002, 293: 1073-1076. PMID: 12051769, DOI: 10.1016/s0006-291x(02)00324-8.Peer-Reviewed Original ResearchConceptsEEF-2KProtein kinaseSerine/threonine protein kinaseCalmodulin-dependent protein kinase IIIElongation factor 2 kinaseEukaryotic protein kinasesProtein translation apparatusProtein kinase IIIC. elegans enzymeThreonine protein kinaseAmino acid sequenceCell surface receptorsIntact enzyme activityTranslation apparatusKinase IIICellular proteinsCell divisionHigh-specificity antibodiesAcid sequenceHuman enzymeStructural domainsKinaseHuman cancersSurface receptorsEnzyme activity
1992
The murine gene encoding the highly conserved Sm B protein contains a nonfunctional alternative 3′ splice site
Griffith A, Schmauss C, Craft J. The murine gene encoding the highly conserved Sm B protein contains a nonfunctional alternative 3′ splice site. Gene 1992, 114: 195-201. PMID: 1376292, DOI: 10.1016/0378-1119(92)90574-9.Peer-Reviewed Original ResearchConceptsSplice site consensus sequenceAlternative splice sitesSplice siteGenomic sequencesSplice junctionsGenomic nucleotide sequencesAmino acid sequenceSite consensus sequencePutative branch pointGenomic lociMurine geneMurine mRNAHuman genesSm polypeptidesB geneNucleotide sequenceB polypeptidesB proteinAcid sequenceConsensus sequenceExon sequencesHuman cellsSecondary structureMurine tissuesGenes
1989
Molecular cloning of cDNA encoding Sm autoantigen: derivation of a cDNA for a B polypeptide of the U series of small nuclear ribonucleoprotein particles.
Ohosone Y, Mimori T, Griffith A, Akizuki M, Homma M, Craft J, Hardin JA. Molecular cloning of cDNA encoding Sm autoantigen: derivation of a cDNA for a B polypeptide of the U series of small nuclear ribonucleoprotein particles. Proceedings Of The National Academy Of Sciences Of The United States Of America 1989, 86: 4249-4253. PMID: 2524838, PMCID: PMC287428, DOI: 10.1073/pnas.86.11.4249.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusSm snRNPsHuman fibroblast cDNA libraryAmino acidsAlternative splicing mechanismLupus erythematosusFibroblast cDNA librarySmall nuclear ribonucleoproteinOpen reading frameAmino acid sequenceSplicing mechanismMolecular cloningCDNA libraryNuclear ribonucleoproteinReading frameAnti-Sm antibodiesB polypeptidesAcid sequenceCOOH terminusNH2 terminusCDNAComplete homologySnRNPsPolypeptide NPolypeptide