2023
Crosstalk within a brain-breast-bone axis regulates mineral and skeletal metabolism during lactation
Athonvarangkul D, Wysolmerski J. Crosstalk within a brain-breast-bone axis regulates mineral and skeletal metabolism during lactation. Frontiers In Physiology 2023, 14: 1121579. PMID: 36875035, PMCID: PMC9979219, DOI: 10.3389/fphys.2023.1121579.Peer-Reviewed Original ResearchBone lossExcess bone lossExcessive bone lossPostmenopausal osteoporosisBone turnoverRare entityMineral metabolismSkeletal metabolismNew therapiesBone qualityCalcium demandOsteoporosisMammary glandCalcium deliveryBone axisReversible physiological responseLactationHormonal signalsCurrent knowledgeMetabolismPhysiological responsesPregnancyHypothalamusPathophysiologyTherapy
2020
Calcium metabolism and breast cancer: Echoes of lactation?
Grinman D, Athonvarungkul D, Wysolmerski J, Jeong J. Calcium metabolism and breast cancer: Echoes of lactation? Current Opinion In Endocrine And Metabolic Research 2020, 15: 63-70. PMID: 33299957, PMCID: PMC7720883, DOI: 10.1016/j.coemr.2020.11.006.BooksBreast cancerSystemic calcium homeostasisBreast cancer cellsMaternal calciumMammary epithelial cellsCalcium metabolismBone metabolismSystemic metabolismIntracellular calciumMalignant behaviorCalcium homeostasisCalcium receptorCalcium secretionSeries of adaptationsUptake of calciumMammary glandEpithelial cellsCalcium transportCancer cellsCell proliferationExtracellular fluidCancerCalciumMetabolismLactationChapter 14 The Onset and Maintenance of Human Lactation and its Endocrine Regulation
Sadovnikova A, Wysolmerski J, Hovey R. Chapter 14 The Onset and Maintenance of Human Lactation and its Endocrine Regulation. 2020, 189-205. DOI: 10.1016/b978-0-12-814823-5.00014-3.Peer-Reviewed Original ResearchEndocrine regulationCopious milk secretionMobilization of fatEpithelial tissuesBone storesMaternal adaptationProgesterone levelsEndocrine changesFood intakeBreast growthBreast epitheliumFetal developmentGlucose productionHuman lactationMilk secretionMammalian reproductionBreastPhysiological changesMother's bodyLactationOnsetTissueKey eventsMilk productionPregnancy
2013
Osteocytes remove and replace perilacunar mineral during reproductive cycles
Wysolmerski JJ. Osteocytes remove and replace perilacunar mineral during reproductive cycles. Bone 2013, 54: 230-236. PMID: 23352996, PMCID: PMC3624069, DOI: 10.1016/j.bone.2013.01.025.BooksConceptsBone lossLevels of PTHrPNegative calcium balanceLevels of estrogenPrincipal bone-resorbing cellsSkeletal calcium storesBone-resorbing cellsPTHrP levelsBone turnoverBone resorptionBone massMineral metabolismCalcium balanceRole of osteocytesCalcium storesMineral homeostasisOsteocytic osteolysisReproductive cycleOsteocytesSystemic demandsPericanalicular matrixCalciumLactationBone
2010
Interactions between breast, bone, and brain regulate mineral and skeletal metabolism during lactation
Wysolmerski JJ. Interactions between breast, bone, and brain regulate mineral and skeletal metabolism during lactation. Annals Of The New York Academy Of Sciences 2010, 1192: 161-169. PMID: 20392232, PMCID: PMC3777748, DOI: 10.1111/j.1749-6632.2009.05249.x.Books