1988
A membrane-anchored form but not the secretory form of human chorionic gonadotropin-alpha chain acquires polylactosaminoglycan.
Fukuda M, Guan J, Rose J. A membrane-anchored form but not the secretory form of human chorionic gonadotropin-alpha chain acquires polylactosaminoglycan. Journal Of Biological Chemistry 1988, 263: 5314-5318. PMID: 2451668, DOI: 10.1016/s0021-9258(18)60717-3.Peer-Reviewed Original ResearchConceptsMembrane-anchored formHuman chorionic gonadotropin (hCG) alpha-subunitMembrane anchoringGonadotropin alpha subunitSecretory formVesicular stomatitis virus glycoproteinMonkey COS-1 cellsCOS-1 cellsMembrane-bound formCytoplasmic domainMembrane proteinsSecretory proteinsComplex-type oligosaccharidesSecretory glycoproteinsProteinDNAVirus glycoproteinSubunitsPolylactosaminoglycansCarbohydrate structuresGlycoproteinGlycansAnchoringAsnEnzyme
1987
Effects of mutations in three domains of the vesicular stomatitis viral glycoprotein on its lateral diffusion in the plasma membrane.
Scullion B, Hou Y, Puddington L, Rose J, Jacobson K. Effects of mutations in three domains of the vesicular stomatitis viral glycoprotein on its lateral diffusion in the plasma membrane. Journal Of Cell Biology 1987, 105: 69-75. PMID: 3038931, PMCID: PMC2114925, DOI: 10.1083/jcb.105.1.69.Peer-Reviewed Original ResearchConceptsCytoplasmic domainTransmembrane domainMutant proteinsMembrane proteinsExtracellular domainWild-type G proteinG proteinsMutant G proteinsVesicular stomatitis viral glycoproteinIntegral membrane proteinsEntire cytoplasmic domainLateral mobilitySite-directed mutagenesisEffects of mutationsCOS-1 cellsSlow mutantsFastest mutantPlasma membraneChimeric proteinType G proteinsG cDNAVirus spike glycoproteinPalmitate additionFluorescence recoveryArtificial bilayers