2023
Long-term neurocognitive outcomes in 204 single-suture craniosynostosis patients
Junn A, Long A, Hauc S, Almeida M, Alper D, Rivera J, Mayes L, Persing J, Alperovich M. Long-term neurocognitive outcomes in 204 single-suture craniosynostosis patients. Child's Nervous System 2023, 39: 1921-1928. PMID: 36877207, DOI: 10.1007/s00381-023-05908-1.Peer-Reviewed Original ResearchConceptsFull Scale IQVisuomotor integrationVisual perceptionVerbal IQNeurocognitive testingVisual perception scoresHigher scoresLong-term neurocognitive outcomesCognitive profileWhite matter connectionsNeurocognitive deficitsIQPerception scoresMean IQNeurocognitive outcomesFrontal lobeLower scoresMotor controlMotor coordinationPerceptionNon-syndromic craniosynostosisUnicoronal synostosisScoresChildren 6
2022
Utilizing Computer-Assisted Design and Virtual Surgical Planning for Correction of Unilateral Lambdoid Synostosis
Long A, Gudbranson E, Almeida M, Chong L, Mozaffari M, Alper D, Rivera J, Persing J, Alperovich M. Utilizing Computer-Assisted Design and Virtual Surgical Planning for Correction of Unilateral Lambdoid Synostosis. Journal Of Craniofacial Surgery 2022, 34: 1036-1038. PMID: 36730112, DOI: 10.1097/scs.0000000000009141.Peer-Reviewed Original ResearchMeSH KeywordsComputer-Aided DesignCranial SuturesCraniosynostosesHumansInfantMaleNeurosurgical ProceduresSkullTomography, X-Ray ComputedConceptsUnilateral lambdoid synostosisLambdoid synostosisSurgical planningCranial vault reconstructionCranial vault remodelingVirtual surgical planningSingle-suture craniosynostosisOperative timePatient presentingSurgical approachTomography scanRare formVault remodelingSynostosisPresentingSurgical modeling
2021
Does different cranial suture synostosis influence orbit volume and morphology in Apert syndrome?
Lu X, Forte A, Alperovich M, Alonso N, Persing J. Does different cranial suture synostosis influence orbit volume and morphology in Apert syndrome? International Journal Of Oral And Maxillofacial Surgery 2021, 51: 338-346. PMID: 34400025, DOI: 10.1016/j.ijom.2021.07.019.Peer-Reviewed Original ResearchConceptsApert syndrome patientsSyndrome patientsBone volumeApert syndromeBicoronal synostosisType IType IIISuture synostosisComputed tomography scanType IIMaxillary bone volumeIndividualized surgical planningOrbital cavity volumeBilateral coronal synostosisTomography scanAnatomic basisBone malformationsSurgical planningSynostosisCoronal synostosisOrbital rimStatistical significanceOrbit volumePatientsSyndrome
2017
De novo mutations in inhibitors of Wnt, BMP, and Ras/ERK signaling pathways in non-syndromic midline craniosynostosis
Timberlake AT, Furey CG, Choi J, Nelson-Williams C, Loring E, Galm A, Kahle K, Steinbacher D, Larysz D, Persing J, Lifton R, Bilguvar K, Mane S, Tikhonova I, Castaldi C, Knight J. De novo mutations in inhibitors of Wnt, BMP, and Ras/ERK signaling pathways in non-syndromic midline craniosynostosis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2017, 114: e7341-e7347. PMID: 28808027, PMCID: PMC5584457, DOI: 10.1073/pnas.1709255114.Peer-Reviewed Original ResearchConceptsBone morphogenetic proteinRas/ERKDe novo mutationsNovo mutationsRas/ERK pathwayDamaging de novo mutationsHigh locus heterogeneityRare syndromic diseaseCommon risk variantsInhibitor of WntSyndromic craniosynostosesNew genesParent-offspring triosSyndromic diseaseMorphogenetic proteinsNegative regulatorERK pathwayMore cranial suturesGenesMidline craniosynostosisRisk variantsWntLocus heterogeneityMutationsExome sequencing
1998
Commentary on Effect of Cranial Suture Autotransplantation From Metopic to Coronal Suture
Persing J. Commentary on Effect of Cranial Suture Autotransplantation From Metopic to Coronal Suture. Journal Of Craniofacial Surgery 1998, 9: 440. PMID: 9780912, DOI: 10.1097/00001665-199809000-00007.Peer-Reviewed Original Research
1994
In the Absence of Periosteum, Transplanted Fetal and Neonatal Rat Coronal Sutures Resist Osseous Obliteration
Opperman L, Persing J, Sheen R, Ogle R. In the Absence of Periosteum, Transplanted Fetal and Neonatal Rat Coronal Sutures Resist Osseous Obliteration. Journal Of Craniofacial Surgery 1994, 5: 327-332. PMID: 7833415, DOI: 10.1097/00001665-199411000-00012.Peer-Reviewed Original ResearchSagittal Synostosis
Ocampo R, Persing J. Sagittal Synostosis. Clinics In Plastic Surgery 1994, 21: 563-574. PMID: 7813156, DOI: 10.1016/s0094-1298(20)30724-0.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsChild, PreschoolCranial SuturesCraniosynostosesCraniotomyHumansInfantParietal Bone
1993
Tissue interactions with underlying dura mater inhibit osseous obliteration of developing cranial sutures
Opperman L, Sweeney T, Redmon J, Persing J, Ogle R. Tissue interactions with underlying dura mater inhibit osseous obliteration of developing cranial sutures. Developmental Dynamics 1993, 198: 312-322. PMID: 8130378, DOI: 10.1002/aja.1001980408.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornCranial SuturesDura MaterEmbryonic and Fetal DevelopmentFetusMaleParietal BoneRatsConceptsDura materCranial baseRat transplant modelParietal boneCranial suturesTransplant modelTransplanted tissueDay 19Fetal dura materBone growthOsseous obliterationWeeksSutureMaterPatencyBiochemical factorsBiomechanical forcesBiomechanical influenceCoronal sutureBoneTissue interactionsSuture patencyOssificationInitial morphogenesisSkull growth
1989
Cranial vault growth in craniosynostosis.
Delashaw J, Persing J, Broaddus W, Jane J. Cranial vault growth in craniosynostosis. Journal Of Neurosurgery 1989, 70: 159-65. PMID: 2913214, DOI: 10.3171/jns.1989.70.2.0159.Peer-Reviewed Original Research
1987
Restricted growth at the frontonasal suture: Alterations in craniofacial growth in rabbits
Babler W, Persing J, Nagorsky M, Jane J. Restricted growth at the frontonasal suture: Alterations in craniofacial growth in rabbits. Developmental Dynamics 1987, 178: 90-98. PMID: 3825967, DOI: 10.1002/aja.1001780112.Peer-Reviewed Original ResearchConceptsDays of ageNewborn New Zealand White rabbitsAnterior lambdoid suturesNew Zealand white rabbitsNasal bone lengthSham-treated groupZealand white rabbitsCranial suturesBilateral implantationBirth weightBilateral applicationWhite rabbitsExperimental animalsApposition of boneNasal boneMorphometric changesPremature closureInternasal sutureAnterior portionYoung rabbitsSignificant decreaseFrontonasal sutureSignificant shorteningSutureBone length
1986
Skull Expansion in Experimental Craniosynostosis
Persing J, Babler W, Nagorsky M, Edgerton M, Jane J, sing J. Skull Expansion in Experimental Craniosynostosis. Plastic & Reconstructive Surgery 1986, 78: 594-603. PMID: 3763746, DOI: 10.1097/00006534-198611000-00006.Peer-Reviewed Original ResearchExternal Cranial Vault Molding after Craniofacial Surgery
Persing J, Nichter L, Jane J, Edgerton M. External Cranial Vault Molding after Craniofacial Surgery. Annals Of Plastic Surgery 1986, 17: 274-283. PMID: 3273106, DOI: 10.1097/00000637-198610000-00002.Peer-Reviewed Original Research
1982
Compensatory growth following premature closure of the coronal suture in rabbits.
Babler W, Persing J, Winn H, Jane J, Rodeheaver G. Compensatory growth following premature closure of the coronal suture in rabbits. Journal Of Neurosurgery 1982, 57: 535-42. PMID: 7108603, DOI: 10.3171/jns.1982.57.4.0535.Peer-Reviewed Original ResearchConceptsEarly surgical releasePremature closureSurgical releaseSuture resultsCoronal sutureAnterior lambdoid suturesNew Zealand white rabbitsZealand white rabbitsDays of ageTransverse sutureWhite rabbitsMorphometric changesCompensatory growthAffected sutureSutureFused suturesLambdoid sutureCranial suturesSkull growth after coronal suturectomy, periostectomy, and dural transection.
Babler W, Persing J, Persson K, Winn H, Jane J, Rodeheaver G. Skull growth after coronal suturectomy, periostectomy, and dural transection. Journal Of Neurosurgery 1982, 56: 529-35. PMID: 7062124, DOI: 10.3171/jns.1982.56.4.0529.Peer-Reviewed Original Research