2022
Benefits of weight loss of 10% or more in patients with overweight or obesity: A review
Tahrani AA, Morton J. Benefits of weight loss of 10% or more in patients with overweight or obesity: A review. Obesity 2022, 30: 802-840. PMID: 35333446, DOI: 10.1002/oby.23371.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Obesity AgentsDiabetes Mellitus, Type 2HumansObesityOverweightPhentermineQuality of LifeTopiramateWeight LossConceptsObesity-related complicationsModest weight lossWeight lossBariatric surgeryLarge weight lossReduced cancer riskWeight-related complicationsCardiovascular risk factorsHealth-related qualityWeight management programType 2 diabetesGreater weight lossMain treatment targetsCost-effective interventionLifestyle modificationLifestyle interventionSevere obesityKnee osteoarthritisSleep apneaRisk factorsCancer riskGlucose metabolismPatientsOverweightTreatment targets
2020
Randomized controlled clinical study evaluating the efficacy and safety of intratumoral treatment of canine mast cell tumors with tigilanol tiglate (EBC‐46)
De Ridder TR, Campbell JE, Burke‐Schwarz C, Clegg D, Elliot EL, Geller S, Kozak W, Pittenger ST, Pruitt JB, Riehl J, White J, Wiest ML, Johannes CM, Morton J, Jones PD, Schmidt PF, Gordon V, Reddell P. Randomized controlled clinical study evaluating the efficacy and safety of intratumoral treatment of canine mast cell tumors with tigilanol tiglate (EBC‐46). Journal Of Veterinary Internal Medicine 2020, 35: 415-429. PMID: 32542733, PMCID: PMC7848366, DOI: 10.1111/jvim.15806.Peer-Reviewed Original ResearchConceptsMast cell tumorsComplete responseControl dogsAdverse eventsIntratumoral treatmentTigilanol tiglateCell tumorsClinical studiesTumor volumeModified Response Evaluation CriteriaTT treatmentOverall complete responseResponse Evaluation CriteriaCanine mast cell tumorsPhase 1Quality of lifeConcomitant medicationsTumor resolutionLocal treatmentTreatment responseSolid tumorsDogsTumorsTreatmentEfficacy
2018
Recommendations on the most suitable quality‐of‐life measurement instruments for bariatric and body contouring surgery: a systematic review
de Vries C, Kalff M, Prinsen C, Coulman K, Haan C, Welbourn R, Blazeby J, Morton J, van Wagensveld B. Recommendations on the most suitable quality‐of‐life measurement instruments for bariatric and body contouring surgery: a systematic review. Obesity Reviews 2018, 19: 1395-1411. PMID: 29883059, DOI: 10.1111/obr.12710.Peer-Reviewed Original ResearchMeSH KeywordsBariatric SurgeryBody ContouringHumansObesityOutcome Assessment, Health CareQuality of LifeReproducibility of ResultsConceptsBariatric surgerySystematic reviewCochrane database systematic reviewsPatient-reported outcome measuresHealth Measurement INstruments (COSMIN) checklistLife measurement instrumentsFuture clinical trialsMeasurement propertiesSystematic literature searchDegree of recommendationFurther validation studiesClinical trialsEligible studiesOutcome measuresLife instrumentsMethodological qualityLiterature searchSurgeryLife measurementsContent validityStrong evidencePoor qualityValidation studyEMBASEReview
2017
Quality of Life After Bariatric Surgery
Mazer LM, Azagury DE, Morton JM. Quality of Life After Bariatric Surgery. Current Obesity Reports 2017, 6: 204-210. PMID: 28527103, DOI: 10.1007/s13679-017-0266-7.Peer-Reviewed Original ResearchMeSH KeywordsBariatric SurgeryHumansMental HealthObesityQuality of LifeRecovery of FunctionTreatment OutcomeWeight LossConceptsQuality of lifeBariatric surgeryDefinition of QoLLife outcomesPatient-reported qualityLong-term QoLConsensus Conference StatementObesity resultsPhysical QoLCurrent evidenceReviewThe purposeSurgeryQoLConference StatementMental healthLasting improvementAbsence of consensusRecent findingsOutcomesInitial studySummaryObesityComorbiditiesFollow
2014
Mesenteric defect closure in laparoscopic Roux-en-Y gastric bypass: a randomized controlled trial
Rosas U, Ahmed S, Leva N, Garg T, Rivas H, Lau J, Russo M, Morton JM. Mesenteric defect closure in laparoscopic Roux-en-Y gastric bypass: a randomized controlled trial. Surgical Endoscopy 2014, 29: 2486-2490. PMID: 25480607, DOI: 10.1007/s00464-014-3970-3.Peer-Reviewed Original ResearchConceptsMesenteric defect closureInternal herniaMesenteric defectDefect closureLaparoscopic RouxGastric bypassComplication rateSignificant differencesPercent excess weight lossExcess weight lossQOL index scoresGI QOLMethods105 patientsGastrointestinal QualityGeneral complicationsInternal herniationOperative timeQOL scoresOpen groupMedical recordsPotential complicationsLRYGBOutcome measuresHigh indexHernia