Combat Exposure Severity Is Associated With Reduced Cortical Thickness in Combat Veterans: A Preliminary Report
Averill LA, Abdallah CG, Pietrzak RH, Averill CL, Southwick SM, Krystal JH, Harpaz-Rotem I. Combat Exposure Severity Is Associated With Reduced Cortical Thickness in Combat Veterans: A Preliminary Report. Chronic Stress 2017, 1: 2470547017724714. PMID: 28845475, PMCID: PMC5568834, DOI: 10.1177/2470547017724714.Peer-Reviewed Original ResearchCombat exposure severityCortical thicknessCombat exposureEarly life trauma exposureExposure severityEarly life stress exposureRostral middle frontal regionsLife stress exposureNon-PTSD groupEarly life stressStructural magnetic resonanceCombat-exposed veteransChildhood Trauma QuestionnaireCombat-exposed controlsCombat Exposure ScaleCortical thinningLeft superior temporalMiddle frontal regionsNegative correlationNeural biomarkersTreatment targetsNeural integritySuperior temporalPTSD psychopathologyChronic stressPosttraumatic Stress Disorder and Depression Symptom Severities Are Differentially Associated With Hippocampal Subfield Volume Loss in Combat Veterans
Averill CL, Satodiya RM, Scott JC, Wrocklage KM, Schweinsburg B, Averill LA, Akiki TJ, Amoroso T, Southwick SM, Krystal JH, Abdallah CG. Posttraumatic Stress Disorder and Depression Symptom Severities Are Differentially Associated With Hippocampal Subfield Volume Loss in Combat Veterans. Chronic Stress 2017, 1: 2470547017744538. PMID: 29520395, PMCID: PMC5839647, DOI: 10.1177/2470547017744538.Peer-Reviewed Original ResearchPosttraumatic stress disorderBeck Depression Inventory scoresClinician-Administered PTSD ScaleCornu ammonis 4Depression Inventory scoresHippocampal subfieldsSymptom severityStress disorderPTSD ScaleAlcohol/substance use disorderHippocampal subfield volume lossHigh-resolution structural magnetic resonance imagingInventory scoresAnterior hippocampal regionsStructural magnetic resonance imagingDepressive symptom severityPrefrontal-amygdala circuitrySubstance use disordersBeck Depression InventoryDepression symptom severityMagnetic resonance imagingPosttraumatic stress disorder groupPosttraumatic stress disorder (PTSD) symptomsCombat-exposed veteransFuture confirmatory studies