2009
Surgical Stress-Induced Immune Cell Redistribution Profiles Predict Short-Term and Long-Term Postsurgical Recovery
Rosenberger PH, Ickovics JR, Epel E, Nadler E, Jokl P, Fulkerson JP, Tillie JM, Dhabhar FS. Surgical Stress-Induced Immune Cell Redistribution Profiles Predict Short-Term and Long-Term Postsurgical Recovery. Journal Of Bone And Joint Surgery 2009, 91: 2783-2794. PMID: 19952239, PMCID: PMC2780920, DOI: 10.2106/jbjs.h.00989.Peer-Reviewed Original ResearchConceptsImmune cell redistributionCell redistributionPostoperative recoveryImmune responseLong-term postoperative recoveryMixed-model repeated-measures analysisProtective immune responseSite of surgeryProspective longitudinal studyOptimum immune responseRepeated-measures analysisLysholm scaleSurgical stressKnee functionPostsurgical recoveryPostoperative healingLeukocyte redistributionSurgeryEnhanced recoveryExtent of recoveryRate of recoveryPatientsPotential mediatorsPhysiological stress responsePoor recovery
2005
Medial Hamstring Tendon Regeneration Following Harvest for Anterior Cruciate Ligament Reconstruction: Fact, Myth, and Clinical Implication
Carofino B, Fulkerson J. Medial Hamstring Tendon Regeneration Following Harvest for Anterior Cruciate Ligament Reconstruction: Fact, Myth, and Clinical Implication. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2005, 21: 1257-1265. PMID: 16226656, DOI: 10.1016/j.arthro.2005.07.002.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnterior Cruciate LigamentAnterior Cruciate Ligament InjuriesBiomechanical PhenomenaHumansKnee JointMagnetic Resonance ImagingPostoperative PeriodRabbitsRecovery of FunctionRegenerationRotationTendonsTissue and Organ HarvestingTorqueTransplantation, AutologousTreatment OutcomeUltrasonographyConceptsAnterior cruciate ligament reconstructionCruciate ligament reconstructionLigament reconstructionKnee flexionMedial hamstring tendonsMajority of patientsSignificant strength deficitsDeep knee flexionMuscle-tendon complexHamstring tendonsStrength deficitsHamstring musclesMuscle bellyRegenerated tendonsScar tissueAnimal modelsFunctional alterationsClinical implicationsTendon complexHistological compositionPeak torqueTendon regenerationTendon resultsTendonGreater deficits