2009
Deep Hypothermic Circulatory Arrest in Patients With High Cognitive Needs: Full Preservation of Cognitive Abilities
Percy A, Widman S, Rizzo JA, Tranquilli M, Elefteriades JA. Deep Hypothermic Circulatory Arrest in Patients With High Cognitive Needs: Full Preservation of Cognitive Abilities. The Annals Of Thoracic Surgery 2009, 87: 117-123. PMID: 19101283, DOI: 10.1016/j.athoracsur.2008.10.025.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAorta, ThoracicAortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationCase-Control StudiesCirculatory Arrest, Deep Hypothermia InducedCognitionCognition DisordersFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient SatisfactionPostoperative CarePreoperative CareProbabilityPsychometricsRadiographyReference ValuesRetrospective StudiesRisk AssessmentSurveys and QuestionnairesTreatment OutcomeVascular Surgical ProceduresConceptsDeep hypothermic circulatory arrestHypothermic circulatory arrestAortic surgeryCirculatory arrestStudy groupStraight deep hypothermic circulatory arrestYale-New Haven HospitalOpen distal anastomosisThoracic aortic surgeryTotal arch replacementArch replacementCerebral protectionPreoperative statusDistal anastomosisSuch patientsFunctional outcomeControl subjectsPatientsSurgeryControl groupAdverse effectsSignificant differencesCognitive changesDaily activitiesOverall score
1999
Failure to Improve Left Ventricular Function After Coronary Revascularization for Ischemic Cardiomyopathy Is Not Associated With Worse Outcome
Samady H, Elefteriades J, Abbott B, Mattera J, McPherson C, Wackers F. Failure to Improve Left Ventricular Function After Coronary Revascularization for Ischemic Cardiomyopathy Is Not Associated With Worse Outcome. Circulation 1999, 100: 1298-1304. PMID: 10491374, DOI: 10.1161/01.cir.100.12.1298.Peer-Reviewed Original ResearchConceptsVentricular functionIschemic cardiomyopathyGroup AHeart failure scoreLeft ventricular functionIschemic LV dysfunctionPoor patient outcomesB. Group ALack of improvementBaseline LVEFEffective revascularizationImproved LVEFCoronary revascularizationLV dysfunctionConsecutive patientsIntraoperative variablesPostoperative improvementCardiac deathLV functionPoor outcomeViable myocardiumLVEF assessmentIschemic myocardiumPatient outcomesWorse outcomes
1998
Procedures for Estimating Growth Rates in Thoracic Aortic Aneurysms
Rizzo J, Coady M, Elefteriades J. Procedures for Estimating Growth Rates in Thoracic Aortic Aneurysms. Journal Of Clinical Epidemiology 1998, 51: 747-754. PMID: 9731923, DOI: 10.1016/s0895-4356(98)00050-x.Peer-Reviewed Original ResearchConceptsTAA growth ratesStatistical problemsStatistical methodsEstimation procedureTAA growthConventional approachesMore reliable resultsInstrumental variable estimationVariable estimationMeasurement errorRate estimatesPrecise estimatesEstimationMeasured growth rateReliable estimatesEstimatesReliable resultsProblemConventional methodsApproachLethal medical conditionError
1995
Cabg in Advanced Left Ventricular Dysfunction
Elefteriades J, Kron I. Cabg in Advanced Left Ventricular Dysfunction. Cardiology Clinics 1995, 13: 35-42. PMID: 7796430, DOI: 10.1016/s0733-8651(18)30060-2.Peer-Reviewed Original ResearchConceptsAdvanced left ventricular dysfunctionCongestive heart failure stateAdvanced ischemic cardiomyopathyEjection fraction increaseIndependent clinical seriesInternal mammary conduitsHeart failure stateLeft ventricular dysfunctionHeart transplantationVentricular dysfunctionIschemic cardiomyopathyPatient groupClinical seriesIschemic muscleCABGPatientsLong-term longevityMuscleUniversity of VirginiaTransplantationCardiomyopathyDysfunctionImportant roleLeft Ventricular Aneurysmectomy in Advanced Left Ventricular Dysfunction
Elefteriades J, Solomon L, Mickleborough L, Cooley D. Left Ventricular Aneurysmectomy in Advanced Left Ventricular Dysfunction. Cardiology Clinics 1995, 13: 59-72. PMID: 7796433, DOI: 10.1016/s0733-8651(18)30062-6.Peer-Reviewed Original Research
1993
Coronary artery bypass grafting in severe left ventricular dysfunction: Excellent survival with improved ejection fraction and functional state
Elefteriades J, Tolis G, Levi E, Mills L, Zaret B. Coronary artery bypass grafting in severe left ventricular dysfunction: Excellent survival with improved ejection fraction and functional state. Journal Of The American College Of Cardiology 1993, 22: 1411-1417. PMID: 8227799, DOI: 10.1016/0735-1097(93)90551-b.Peer-Reviewed Original ResearchMeSH KeywordsActuarial AnalysisAdultAgedAged, 80 and overCause of DeathCoronary Artery BypassDefibrillators, ImplantableFemaleFollow-Up StudiesHeart DiseasesHospital MortalityHumansIntra-Aortic Balloon PumpingMaleMammary ArteriesMiddle AgedPrognosisQuality of LifeSeverity of Illness IndexStroke VolumeSurvival RateVentricular Function, LeftConceptsCoronary Artery Bypass GraftingArtery Bypass GraftingCoronary artery bypassSevere left ventricular dysfunctionLeft ventricular ejection fractionInternal mammary arteryLeft ventricular dysfunctionVentricular ejection fractionEjection fractionArtery bypassVentricular dysfunctionBypass GraftingMammary arteryMortality rateCanadian Cardiovascular Society angina classCongestive heart failure classGood medium-term survivalAdvanced ischemic cardiomyopathyAdvanced ventricular dysfunctionHeart failure classImproved ejection fractionHospital mortality rateCongestive heart failureIntraaortic balloon pumpSignificant ventricular arrhythmias
1992
Strategies in the Surgical Treatment of Malignant Ventricular Arrhythmias An 8-year Experience
GEHA A, ELEFTERIADES J, HSU J, BIBLO L, HOCH D, BATSFORD W, ROSENFELD L, CARLSON M, JOHNSON N, WALDO A. Strategies in the Surgical Treatment of Malignant Ventricular Arrhythmias An 8-year Experience. Annals Of Surgery 1992, 216: 309-317. PMID: 1417180, PMCID: PMC1242614, DOI: 10.1097/00000658-199209000-00010.Peer-Reviewed Original ResearchConceptsAutomatic implantable cardioverter defibrillatorSubendocardial resectionVentricular tachycardiaSurgical treatmentLV aneurysmSudden deathThirty-day mortality rateSevere LV dysfunctionCongestive heart failureRecurrent ventricular tachycardiaSignificant myocardial ischemiaLong-term survivorsMalignant ventricular arrhythmiasMalignant ventricular tachyarrhythmiasCent of survivorsImplantable cardioverter defibrillatorLong-term survivalActuarial survivalAntiarrhythmic medicationsLate deathsComparable patientsLV dysfunctionConsecutive patientsHeart failureVentricular arrhythmiasLong-Term Follow-up of Bilateral Pacing of the Diaphragm in Quadriplegia
Elefteriades J, Hogan J, Handler A, Loke J. Long-Term Follow-up of Bilateral Pacing of the Diaphragm in Quadriplegia. New England Journal Of Medicine 1992, 326: 1433-1434. PMID: 1569991, DOI: 10.1056/nejm199205213262113.Peer-Reviewed Original ResearchIs Cardiopulmonary Bypass Effective for Treatment of Hypothermic Arrest due to Drowning or Exposure?
Letsou G, Kopf G, Elefteriades J, Carter J, Baldwin J, Hammond G. Is Cardiopulmonary Bypass Effective for Treatment of Hypothermic Arrest due to Drowning or Exposure? JAMA Surgery 1992, 127: 525-528. PMID: 1575622, DOI: 10.1001/archsurg.1992.01420050045005.Peer-Reviewed Original ResearchConceptsCardiopulmonary bypassHypothermic arrestMedian sternotomyEmergency hospital admissionsNormal neurologic functionFull cardiopulmonary arrestFreshwater drowningHospital admissionNeurologic functionSinus bradycardiaSuch patientsThree patientsCardiopulmonary arrestFourth patientVentricular fibrillationPatientsBypassSternotomyCore temperatureResuscitationArrestExposureAsystoleBradycardiaDrowningLong-term experience with descending aortic dissection: The complication-specific approach
Elefteriades J, Hartleroad J, Gusberg R, Salazar A, Black H, Kopf G, Baldwin J, Hammond G. Long-term experience with descending aortic dissection: The complication-specific approach. The Annals Of Thoracic Surgery 1992, 53: 11-21. PMID: 1728218, DOI: 10.1016/0003-4975(92)90752-p.Peer-Reviewed Original ResearchConceptsComplication-specific approachAortic dissectionActuarial survivalGraft replacementComplications of dissectionLower intercostal arteriesLeft subclavian arteryLong-term resultsUncomplicated dissectionLimb ischemiaPostoperative studiesSubclavian arteryFalse lumenSurgical managementIntercostal arteriesRadiographic findingsComplicated dissectionFenestration procedurePatientsSaccular aneurysmLong-term experienceAortaWhole groupDissectionFenestration
1990
Heart-lung transplantation: initial experience in New England.
Letsou G, Franco K, Kopf G, Dewar M, Elefteriades J, Hammond G, Baldwin J. Heart-lung transplantation: initial experience in New England. Connecticut Medicine 1990, 54: 419-24. PMID: 2225808.Peer-Reviewed Original ResearchConceptsPulmonary hypertensionEnd-stage cardiopulmonary diseaseAssociated pulmonary hypertensionNormal cardiopulmonary functionHeart-lung transplantationHeart-lung transplantsPrimary pulmonary hypertensionDoxorubicin-induced cardiomyopathyPulse steroidsRejection episodesDonor surgeryFluid overloadCardiopulmonary bypassCardiopulmonary functionCardiopulmonary diseaseEffective therapyPrimary disorderFunctional capacityPatientsCystic fibrosisInitial experienceGraftAge 33HypertensionAge 16Fenestration Revisited: A Safe and Effective Procedure for Descending Aortic Dissection
Elefteriades J, Hammond G, Gusberg R, Kopf G, Baldwin J. Fenestration Revisited: A Safe and Effective Procedure for Descending Aortic Dissection. JAMA Surgery 1990, 125: 786-790. PMID: 2346378, DOI: 10.1001/archsurg.1990.01410180112018.Peer-Reviewed Original ResearchEvolving patterns in the surgical treatment of malignant ventricular tachyarrhythmias
Elefteriades J, Biblo L, Batsford W, Rosenfeld L, Henthorn R, Carlson M, Waldo A, Hsu J, Geha A. Evolving patterns in the surgical treatment of malignant ventricular tachyarrhythmias. The Annals Of Thoracic Surgery 1990, 49: 94-100. PMID: 2297279, DOI: 10.1016/0003-4975(90)90362-a.Peer-Reviewed Original ResearchConceptsAutomatic implantable cardioverter defibrillatorResection groupThirty-day mortalityCoronary artery bypassMalignant ventricular tachyarrhythmiasIntractable ventricular arrhythmiasImplantable cardioverter defibrillatorAICD placementArtery bypassSurgical treatmentEndocardial resectionVentricular arrhythmiasVentricular tachyarrhythmiasAntiarrhythmic agentsSudden deathCardioverter defibrillatorResectionMortality figuresPatientsEffective interventionsGreatest overall benefitSurvivalGroupOverall benefitValuable alternative
1987
Long-term performance of the St. Jude Medical valve: low incidence of thromboembolism and hemorrhagic complications with modest doses of warfarin.
Kopf G, Hammond G, Geha A, Elefteriades J, Hashim S. Long-term performance of the St. Jude Medical valve: low incidence of thromboembolism and hemorrhagic complications with modest doses of warfarin. Circulation 1987, 76: iii132-6. PMID: 3621536.Peer-Reviewed Original ResearchConceptsSt. Jude Medical valveJude Medical valveModest dosesHemorrhagic complicationsLower incidenceValve failureLate cardiac deathStructural valve failureDouble valve replacementPercent of patientsOccurrence of thromboembolismHospital survivorsAnticoagulation regimenPerivalvular leakValve thrombosisValve replacementCardiac deathProthrombin timeMitral positionThromboembolismPatientsComplicationsThrombosisWarfarinIncidence