2024
The role of anatomic shape features in the prognosis of uncomplicated type B aortic dissection initially treated with optimal medical therapy
Liu M, Dong H, Mazlout A, Wu Y, Kalyanasundaram A, Oshinski J, Sun W, Elefteriades J, Leshnower B, Gleason R. The role of anatomic shape features in the prognosis of uncomplicated type B aortic dissection initially treated with optimal medical therapy. Computers In Biology And Medicine 2024, 170: 108041. PMID: 38330820, PMCID: PMC10932856, DOI: 10.1016/j.compbiomed.2024.108041.Peer-Reviewed Original ResearchConceptsType B aortic dissectionTreated with optimal medical therapyAortic growth rateOptimal medical therapyUncomplicated type B aortic dissectionB aortic dissectionMedical therapyCT scanPatients' long-term survivalType B aortic dissection patientsLong-term outcomesLong-term survivalFailure groupAortic expansionChronic phaseFailure patientsPatientsCT imagesTherapyDissectionStatistical shape modelFailurePrognosisScanningRegression
2023
Aortic Size at the Time of Type A and Type B Dissections
Perez Z, Zafar M, Velasco J, Sonsino A, Ellauzi H, John C, Kalyanasundaram A, Ziganshin B, Elefteriades J. Aortic Size at the Time of Type A and Type B Dissections. The Annals Of Thoracic Surgery 2023, 116: 262-268. PMID: 37062339, DOI: 10.1016/j.athoracsur.2023.03.037.Peer-Reviewed Original ResearchConceptsType B dissectionTime of dissectionB dissectionAortic sizeAortic diameterBicuspid aortic valveThoracic aortic aneurysmAortic interventionAortic dissectionSurgical interventionAortic aneurysmFemale sexAortic valveThoracic aortaProphylactic repairUnadjusted regressionLeft shiftLogistic regressionDissectionNew guidelinesType ASize criteriaOddsInterventionTime of typesKIF6 Trp719Arg Genetic Variant Increases Risk for Thoracic Aortic Dissection
Velasco J, Li Y, Ziganshin B, Zafar M, Rizzo J, Ma D, Zang H, Kalyanasundaram A, Elefteriades J. KIF6 Trp719Arg Genetic Variant Increases Risk for Thoracic Aortic Dissection. Genes 2023, 14: 252. PMID: 36833179, PMCID: PMC9956195, DOI: 10.3390/genes14020252.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmAortic dissectionOdds ratioVariant statusArg allele carriersThoracic aortic dissectionOccurrence of ADAortic sizeArg alleleMarked adverse impactTAA patientsAortic aneurysmClinical assessmentSurgical decisionAllele carriersIncrease riskVariant patientsArg carriersPilot studyDissectionImportant intracellular functionsConfirmatory findingsPatientsAneurysmsPresent study
2022
Ultimate tensile strength and biaxial stress–strain responses of aortic tissues—A clinical-engineering correlation
Dong H, Liu M, Lou X, Leshnower B, Sun W, Ziganshin B, Zafar M, Elefteriades J. Ultimate tensile strength and biaxial stress–strain responses of aortic tissues—A clinical-engineering correlation. Applications In Engineering Science 2022, 10: 100101. DOI: 10.1016/j.apples.2022.100101.Peer-Reviewed Original ResearchThoracic aortic dissectionAortic dissectionAortic tissueDissection eventsBicuspid aortic valveUnderlying genetic abnormalitiesHuman aortic tissueHypertensive episodesAortic arch morphologyAortic valveAdvanced ageTissue injuryConnective tissue ingrowthAged animalsAortic wallInciting factorsGenetic abnormalitiesClinical contextArch morphologyDissectionDissected tissuesTissueResponseTissue ingrowthInjury
2021
Delayed Surgery for Acute Aortic Dissection
Pinkhasova P, Zafar M, Ziganshin B, Elefteriades J. Delayed Surgery for Acute Aortic Dissection. 2021, 535-551. DOI: 10.1007/978-3-030-66668-2_37.Peer-Reviewed Original ResearchAcute Type A Aortic Dissection
Elefteriades J, Ziganshin B. Acute Type A Aortic Dissection. 2021, 187-200. DOI: 10.1007/978-3-030-78877-3_60.Peer-Reviewed Original ResearchDo Not Obliterate the False Lumen in a Chronic Aortic Dissection
Elefteriades J, Ziganshin B. Do Not Obliterate the False Lumen in a Chronic Aortic Dissection. 2021, 83-84. DOI: 10.1007/978-3-030-78877-3_29.Peer-Reviewed Original ResearchAcute Type B Aortic Dissection: Clinical Perspectives to Guide Surgery
Elefteriades J, Ziganshin B. Acute Type B Aortic Dissection: Clinical Perspectives to Guide Surgery. 2021, 227-232. DOI: 10.1007/978-3-030-78877-3_63.Peer-Reviewed Original Research
2019
Triggers of Aortic Dissection
Ziganshin B, Elefteriades J. Triggers of Aortic Dissection. 2019, 191-203. DOI: 10.1007/978-3-7091-4874-7_13.Peer-Reviewed Original Research
2018
Chapter 3 Histology of Aortic Disease and Progression of Aortic Dissection From Acute to Chronic
Zafar M, Peterss S, Ziganshin B, Elefteriades J. Chapter 3 Histology of Aortic Disease and Progression of Aortic Dissection From Acute to Chronic. 2018, 41-59. DOI: 10.1016/b978-0-12-809979-7.00003-1.Peer-Reviewed Original ResearchChronic stateUncomplicated acute type B dissectionAcute type B dissectionAcute Stanford typeType B dissectionEarly surgical interventionTreatment of choiceChronic dissectionB dissectionStanford typeAortic dissectionMedical therapyAortic diseaseSurgical interventionDissectionAortaTemporal courseHistologyMorphological changesAcuteChronicHistopathologyTherapyDiseaseProgression
2015
CHRONOLOGIC AND CLIMATIC FACTORS PRECIPITATE ACUTE AORTIC DISSECTION: A STUDY OF 1642 PATIENTS IN TWO CONTINENTS
Ma W, Li B, Ziganshin B, Zhang W, Wang L, Sarkar A, Pan X, Liu N, Zheng J, Liu Y, Zhu J, Huang L, Sun L, Elefteriades J. CHRONOLOGIC AND CLIMATIC FACTORS PRECIPITATE ACUTE AORTIC DISSECTION: A STUDY OF 1642 PATIENTS IN TWO CONTINENTS. Journal Of The American College Of Cardiology 2015, 65: a2112. DOI: 10.1016/s0735-1097(15)62112-x.Peer-Reviewed Original Research
2005
Epi-aortic ultrasound for cannulating the true lumen of a thoracic dissection — A case report
Popescu W, McCloskey G, Barash P, Elefteriades J. Epi-aortic ultrasound for cannulating the true lumen of a thoracic dissection — A case report. International Journal Of Angiology 2005, 258-259. DOI: 10.1055/s-0031-1276515.Peer-Reviewed Original Research
1998
Experimental confirmation of effectiveness of fenestration in acute aortic dissection
Morales D, Quin J, Braxton J, Hammond G, Gusberg R, Elefteriades J. Experimental confirmation of effectiveness of fenestration in acute aortic dissection. The Annals Of Thoracic Surgery 1998, 66: 1679-1683. PMID: 9875771, DOI: 10.1016/s0003-4975(98)00901-1.Peer-Reviewed Original ResearchConceptsRenal arterial flowFemoral blood pressureAortic dissectionBlood pressureAortic fenestrationAortic distensibilityCarotid pressureArterial flowAcute aortic dissectionML/minSubsequent fenestrationOrgan ischemiaRenal flowInfrarenal aortaContinued clinical applicationBlood flowAnimal modelsFenestrationDissectionClinical applicationT-testDistensibilityMinIschemiaAorta
1997
Multimodality serial follow-up of thoracic aortic aneurysms
Rizzo J, Darr U, Fischer M, Johnson K, Finkle J, Gusberg R, Kopf G, Abbott T, Shevchenko I, Elefteriades J. Multimodality serial follow-up of thoracic aortic aneurysms. International Journal Of Angiology 1997, 6: 153-156. DOI: 10.1007/bf01616173.Peer-Reviewed Original ResearchThoracic aortaAortic dissectionMale patientsLarge aneurysmsMultivariate risk factor analysisYale-New Haven HospitalThoraco-abdominal aortaThoracic aortic aneurysmThoracic aorta aneurysmRisk factor analysisDiagnostic imaging testsTime of dissectionAortic expansionSurgical interventionAortic aneurysmAorta aneurysmImaging testsTime of rupturePatientsAneurysmsAortaImaging studiesDissectionLong-term survival prospectsLower survival
1992
Long-term experience with descending aortic dissection: The complication-specific approach
Elefteriades J, Hartleroad J, Gusberg R, Salazar A, Black H, Kopf G, Baldwin J, Hammond G. Long-term experience with descending aortic dissection: The complication-specific approach. The Annals Of Thoracic Surgery 1992, 53: 11-21. PMID: 1728218, DOI: 10.1016/0003-4975(92)90752-p.Peer-Reviewed Original ResearchConceptsComplication-specific approachAortic dissectionActuarial survivalGraft replacementComplications of dissectionLower intercostal arteriesLeft subclavian arteryLong-term resultsUncomplicated dissectionLimb ischemiaPostoperative studiesSubclavian arteryFalse lumenSurgical managementIntercostal arteriesRadiographic findingsComplicated dissectionFenestration procedurePatientsSaccular aneurysmLong-term experienceAortaWhole groupDissectionFenestration
1990
Fenestration Revisited: A Safe and Effective Procedure for Descending Aortic Dissection
Elefteriades J, Hammond G, Gusberg R, Kopf G, Baldwin J. Fenestration Revisited: A Safe and Effective Procedure for Descending Aortic Dissection. JAMA Surgery 1990, 125: 786-790. PMID: 2346378, DOI: 10.1001/archsurg.1990.01410180112018.Peer-Reviewed Original Research