2019
Robust olfactory responses in the absence of odorant binding proteins
Xiao S, Sun JS, Carlson JR. Robust olfactory responses in the absence of odorant binding proteins. ELife 2019, 8: e51040. PMID: 31651397, PMCID: PMC6814364, DOI: 10.7554/elife.51040.Peer-Reviewed Original ResearchConceptsOdorant binding proteinsOlfactory responsesBinding proteinAntennae of insectsHydrophobic odorantsSensilla typesOlfactory physiologyOlfactory sensillaFunctional typesBasiconic sensillaOBPsAntennal basiconic sensillaOdor receptorsSensillaProteinDiverse chemicalsInsectsOdorantsMutantsBehavioral responsesGenesOvipositionPhysiologyHigh levelsResponse
2008
Translation of Sensory Input into Behavioral Output via an Olfactory System
Kreher SA, Mathew D, Kim J, Carlson JR. Translation of Sensory Input into Behavioral Output via an Olfactory System. Neuron 2008, 59: 110-124. PMID: 18614033, PMCID: PMC2496968, DOI: 10.1016/j.neuron.2008.06.010.Peer-Reviewed Original ResearchA Regulatory Code for Neuron-Specific Odor Receptor Expression
Ray A, van Naters W, Carlson JR. A Regulatory Code for Neuron-Specific Odor Receptor Expression. PLOS Biology 2008, 6: e125. PMID: 18846726, PMCID: PMC2430909, DOI: 10.1371/journal.pbio.0060125.Peer-Reviewed Original ResearchConceptsOlfactory receptor neuronsORN classesAxon guidance genesOdor receptorsAmino acid sequenceMost olfactory receptor neuronsReceptor gene regulationDrosophila speciesPhylogenetic approachGene regulationGenome sequenceTranscription factorsIndividual olfactory receptor neuronsRegulatory elementsAcid sequenceChemosensory organsRegulatory codeGenetic analysisMaxillary palpsGenesLarge repertoireReceptor neuronsReceptor geneExpressionNeuron map
2007
Mechanisms of Odor Receptor Gene Choice in Drosophila
Ray A, van Naters Wv, Shiraiwa T, Carlson JR. Mechanisms of Odor Receptor Gene Choice in Drosophila. Neuron 2007, 53: 353-369. PMID: 17270733, PMCID: PMC1986798, DOI: 10.1016/j.neuron.2006.12.010.Peer-Reviewed Original ResearchConceptsReceptor gene choiceOlfactory receptor neuronsGene choiceNegative regulatory elementAsymmetric segregationAlternative splicingNegative feedback regulationSingle geneTranscription factorsORN classesRegulatory elementsCombinatorial codeDicistronic mRNACommon progenitorMutational analysisDrosophilaRegulatory factorsOlfactory organFeedback regulationOdor receptorsReceptor neuronsReceptor geneGenesNeuron mapReceptor repertoire
2005
The Molecular Basis of Odor Coding in the Drosophila Larva
Kreher SA, Kwon JY, Carlson JR. The Molecular Basis of Odor Coding in the Drosophila Larva. Neuron 2005, 46: 445-456. PMID: 15882644, DOI: 10.1016/j.neuron.2005.04.007.Peer-Reviewed Original ResearchConceptsOlfactory receptor neuronsDrosophila larvaeMolecular basisVivo expression systemDifferent olfactory systemsFamily of receptorsSingle olfactory receptor neuronsLarval brainSpecificity mapsLarval antennal lobeExpression systemMolecular mechanismsOdor codingOdor receptorsReceptor neuronsIndividual receptorsAntennal lobeLongstanding observationGenesOlfactory systemLarvaeBreadth of tuningSingle glomerulusReceptorsOdor informationCoexpression of Two Functional Odor Receptors in One Neuron
Goldman AL, van Naters W, Lessing D, Warr CG, Carlson JR. Coexpression of Two Functional Odor Receptors in One Neuron. Neuron 2005, 45: 661-666. PMID: 15748842, DOI: 10.1016/j.neuron.2005.01.025.Peer-Reviewed Original Research
2003
Integrating the Molecular and Cellular Basis of Odor Coding in the Drosophila Antenna
Dobritsa AA, van Naters W, Warr CG, Steinbrecht RA, Carlson JR. Integrating the Molecular and Cellular Basis of Odor Coding in the Drosophila Antenna. Neuron 2003, 37: 827-841. PMID: 12628173, DOI: 10.1016/s0896-6273(03)00094-1.Peer-Reviewed Original ResearchConceptsAb3A neuronsEctopic expressionTransgenic rescue experimentsWild-type cellsDrosophila olfactory systemOdor ligandsDeletion mutantsDrosophila antennaCells identifiesGene expressionRescue experimentsCellular mapsSexual dimorphismReceptor gene expressionCellular basisOr22aOdor receptorsReceptor geneSingle cellsGenesOlfactory systemExpressionOdor codingDendritic membraneCells