2012
Examining the relation between the serotonin transporter 5-HTTPLR genotype x trauma exposure interaction on a contemporary phenotypic model of posttraumatic stress symptomatology: A pilot study
Pietrzak RH, Galea S, Southwick SM, Gelernter J. Examining the relation between the serotonin transporter 5-HTTPLR genotype x trauma exposure interaction on a contemporary phenotypic model of posttraumatic stress symptomatology: A pilot study. Journal Of Affective Disorders 2012, 148: 123-128. PMID: 23183127, PMCID: PMC3604029, DOI: 10.1016/j.jad.2012.11.003.Peer-Reviewed Original ResearchAdolescentAdultAgedAged, 80 and overCyclonic StormsDisastersFemaleGene-Environment InteractionGenetic Predisposition to DiseaseGenotypeHumansMaleMiddle AgedModels, GeneticPhenotypePilot ProjectsPolymorphism, GeneticQualitative ResearchSerotonin Plasma Membrane Transport ProteinsStress Disorders, Post-TraumaticYoung AdultGenetic influences of resting state fMRI activity in language-related brain regions in healthy controls and schizophrenia patients: a pilot study
Jamadar S, Powers NR, Meda SA, Calhoun VD, Gelernter J, Gruen JR, Pearlson GD. Genetic influences of resting state fMRI activity in language-related brain regions in healthy controls and schizophrenia patients: a pilot study. Brain Imaging And Behavior 2012, 7: 15-27. PMID: 22669497, PMCID: PMC4428558, DOI: 10.1007/s11682-012-9168-1.Peer-Reviewed Original Research
2010
Early-life stress, corticotropin-releasing factor, and serotonin transporter gene: A pilot study
Coplan JD, Abdallah CG, Kaufman J, Gelernter J, Smith EL, Perera TD, Dwork AJ, Kaffman A, Gorman JM, Rosenblum LA, Owens MJ, Nemeroff CB. Early-life stress, corticotropin-releasing factor, and serotonin transporter gene: A pilot study. Psychoneuroendocrinology 2010, 36: 289-293. PMID: 20692103, PMCID: PMC3017732, DOI: 10.1016/j.psyneuen.2010.07.011.Peer-Reviewed Original ResearchConceptsEarly life stressCSF CRF concentrationsCRF concentrationsCerebrospinal fluid corticotropin-releasing factor concentrationsCorticotropin-releasing factor concentrationsPilot studyNonhuman primate modelCorticotropin-releasing factorYears of ageEarly life adversitySerotonin transporter gene polymorphismPersistent elevationTransporter gene polymorphismPrimate modelMajor depressionCSF samplesDepressive symptomsGene polymorphismsAllele groupFactor concentrationsLFD conditionsMale bonnet macaquesChildhood abuseSubsequent developmentBonnet macaques
2009
A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia
Meda SA, Jagannathan K, Gelernter J, Calhoun VD, Liu J, Stevens MC, Pearlson GD. A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia. NeuroImage 2009, 53: 1007-1015. PMID: 19944766, PMCID: PMC3968678, DOI: 10.1016/j.neuroimage.2009.11.052.Peer-Reviewed Original ResearchMeSH KeywordsAcoustic StimulationBrain MappingBrain-Derived Neurotrophic FactorDopamine Plasma Membrane Transport ProteinsEndophenotypesFemaleGenetic Predisposition to DiseaseGenotypeHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleNeural PathwaysPilot ProjectsPolymorphism, Single NucleotideSchizophreniaSerotonin Plasma Membrane Transport ProteinsConceptsDopamine transporterBrain functionNeurotropic factorAuditory oddball taskSchizophrenia patientsSingle nucleotide polymorphismsMultiple risk genesRisk genesOddball taskRelated brain functionsHealthy controlsSchizophrenia risk genesAbnormal activationGenomic factorsTemporal gyrusPatientsTask-relevant regionsSchizophreniaSignificant differencesAttention/Multiple single nucleotide polymorphismsGenetic profilePsychiatric neuroimagingBrainGenotype-phenotype relationships
2002
Sensory gating and psychosis vulnerability in cocaine-dependent individuals: preliminary data
Boutros NN, Gelernter J, Gooding DC, Cubells J, Young A, Krystal JH, Kosten T. Sensory gating and psychosis vulnerability in cocaine-dependent individuals: preliminary data. Biological Psychiatry 2002, 51: 683-686. PMID: 11955469, DOI: 10.1016/s0006-3223(01)01237-9.Peer-Reviewed Original Research