2001
Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock.
Gallouzi IE, Brennan CM, Steitz JA. Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock. RNA 2001, 7: 1348-61. PMID: 11565755, PMCID: PMC1370177, DOI: 10.1017/s1355838201016089.Peer-Reviewed Original ResearchMeSH KeywordsActive Transport, Cell NucleusAntigens, SurfaceCarrier ProteinsCytoplasmELAV ProteinsELAV-Like Protein 1Fatty Acids, UnsaturatedHeat-Shock ResponseHeLa CellsHumansKaryopherinsLigandsNeuropeptidesNuclear ProteinsPhosphoproteinsReceptors, Cytoplasmic and NuclearRNA, MessengerRNA-Binding ProteinsConceptsAU-rich elementsNuclear exportHeat shockMessenger RNANuclear export factor CRM1Protein ligandsInhibitor of CRM1Export factor CRM1CRM1-dependent exportMRNA nuclear exportRNA-binding proteinProtein-protein interactionsRapid mRNA turnoverEarly response genesAssociation of HuRHeat shock inducesCytoplasmic fociHnRNP complexesExport pathwayMRNA turnoverLeptomycin BCoimmunoprecipitation experimentsCytoplasmic interactionsNES domainResponse genes
1995
Isolation and characterization of a novel, low abundance hnRNP protein: A0.
Myer VE, Steitz JA. Isolation and characterization of a novel, low abundance hnRNP protein: A0. RNA 1995, 1: 171-82. PMID: 7585247, PMCID: PMC1369071.Peer-Reviewed Original ResearchConceptsHnRNP A0HnRNP proteinsGlycine-rich C-terminusHeterogeneous nuclear ribonucleoprotein complexesB familyLow-abundance membersPre-messenger RNATwo-dimensional gel electrophoresisCharacteristic primary structureNuclear ribonucleoprotein complexesVariety of proteinsB family membersRibonucleoprotein complexesHnRNP complexesMammalian cellsMRNA stabilityC-terminusPrimary structureProtease mappingProteinRNA probesGel electrophoresisBasic proteinMajor classesRNA