Hepatitis C virus (HCV) disease progression in people who inject drugs (PWID): A systematic review and meta-analysis
Smith DJ, Combellick J, Jordan AE, Hagan H. Hepatitis C virus (HCV) disease progression in people who inject drugs (PWID): A systematic review and meta-analysis. International Journal Of Drug Policy 2015, 26: 911-921. PMID: 26298331, PMCID: PMC4577462, DOI: 10.1016/j.drugpo.2015.07.004.Peer-Reviewed Original ResearchConceptsFibrosis progression rateHepatocellular carcinomaDisease progressionIncidence rateProgression rateHepatitis C virus disease progressionStage-specific fibrosis progression ratesPrevious injection drug useChronic HCV infectionPrognosis Studies toolPooled incidence rateInjection drug useDisease progression rateBurden of diseaseStudy inclusion criteriaNew drug regimensPeriod of infectiousnessRandom-effects modelMETAVIR unitsHCV infectionAdvanced fibrosisDrug regimensHCV preventionStage F3Inclusion criteriaHepatitis C Virus Disease Progression in People Who Inject Drugs: Protocol for a Systematic Review and Meta-Analysis
Combellick J, Smith DJ, Jordan AE, Hagan H. Hepatitis C Virus Disease Progression in People Who Inject Drugs: Protocol for a Systematic Review and Meta-Analysis. JMIR Research Protocols 2015, 4: e68. PMID: 26054636, PMCID: PMC4526911, DOI: 10.2196/resprot.4518.Peer-Reviewed Original ResearchSystematic reviewNatural historyDisease progressionHepatocellular carcinomaHepatitis C virus disease progressionHepatitis C virus infectionC virus infectionLiver-related mortalityInjection drug useEffect of preventionChronic HCVHCV managementFibrosis progressionViral clearanceDisease burdenTreatment strategiesVirus infectionIndividual patientsHCVDrug useMeta-AnalysisPWIDProgressionCirrhosisMajority of people