Bioactive gel self-assembled from phosphorylate biomimetic peptide: A potential scaffold for enhanced osteogenesis
Quan C, Zhang Z, Liang P, Zheng J, Wang J, Hou Y, Tang Q. Bioactive gel self-assembled from phosphorylate biomimetic peptide: A potential scaffold for enhanced osteogenesis. International Journal Of Biological Macromolecules 2018, 121: 1054-1060. PMID: 30359655, DOI: 10.1016/j.ijbiomac.2018.10.148.Peer-Reviewed Original ResearchConceptsRat marrow mesenchymal stem cellsRunt-related transcription factor 2Biomimetic peptidesTranscription factor 2Micro-CT 3D reconstructionMarrow mesenchymal stem cellsRT-PCR analysisOsteogenesis-related genesRegeneration patternsMesenchymal stem cellsThree-dimensional hydrogelsRat cranial boneBMP-2Stem cellsAlkaline phosphataseFactor 2Cell adhesion peptidesOsteoinductive cytokinesCritical roleAdhesion peptidesBioactive moleculesBone regenerationBetter expressionOsteopontinEnhanced osteogenesis