2022
Bioactive gelatin cryogels with BMP‐2 biomimetic peptide and VEGF: A potential scaffold for synergistically induced osteogenesis
Wang L, Chen L, Wang J, Wang L, Gao C, Li B, Wang Y, Wu J, Quan C. Bioactive gelatin cryogels with BMP‐2 biomimetic peptide and VEGF: A potential scaffold for synergistically induced osteogenesis. Chinese Chemical Letters 2022, 33: 1956-1962. DOI: 10.1016/j.cclet.2021.10.070.Peer-Reviewed Original ResearchGelatin cryogelCranial bone defect modelRat cranial bone defect modelMicro-CT 3D reconstructionBone defect modelGelatin scaffoldsBiomaterial-based therapiesBone regeneration patternsSide edgesPoor biocompatibilityRat bone marrow mesenchymal stem cellsBone regenerationPotential scaffoldBone repairDefect modelCryogelsPrepared cryogelsBiomimetic peptidesCell attachmentScaffoldsCenter areaCell experiments
2018
Bioactive gel self-assembled from phosphorylate biomimetic peptide: A potential scaffold for enhanced osteogenesis
Quan C, Zhang Z, Liang P, Zheng J, Wang J, Hou Y, Tang Q. Bioactive gel self-assembled from phosphorylate biomimetic peptide: A potential scaffold for enhanced osteogenesis. International Journal Of Biological Macromolecules 2018, 121: 1054-1060. PMID: 30359655, DOI: 10.1016/j.ijbiomac.2018.10.148.Peer-Reviewed Original ResearchConceptsRat marrow mesenchymal stem cellsRunt-related transcription factor 2Biomimetic peptidesTranscription factor 2Micro-CT 3D reconstructionMarrow mesenchymal stem cellsRT-PCR analysisOsteogenesis-related genesRegeneration patternsMesenchymal stem cellsThree-dimensional hydrogelsRat cranial boneBMP-2Stem cellsAlkaline phosphataseFactor 2Cell adhesion peptidesOsteoinductive cytokinesCritical roleAdhesion peptidesBioactive moleculesBone regenerationBetter expressionOsteopontinEnhanced osteogenesis