2022
Glucocorticoid minimizes local anesthetic infusion requirement through adductor canal block and improves perioperative prosthetic joint range of motion in total knee arthroplasty
Baldev K, Dai F, Barrett C, Zhou B, Shah M, Howie B, Boominathan P, Zhao X, Li J. Glucocorticoid minimizes local anesthetic infusion requirement through adductor canal block and improves perioperative prosthetic joint range of motion in total knee arthroplasty. PLOS ONE 2022, 17: e0261949. PMID: 35081134, PMCID: PMC8791457, DOI: 10.1371/journal.pone.0261949.Peer-Reviewed Original ResearchConceptsAdductor canal blockTotal knee arthroplastyContinuous adductor canal blockPain scoresCanal blockTreatment groupsKnee arthroplastyOpioid consumptionOpioid usageGlucocorticoid injectionSingle-injection adductor canal blockControl groupSingle-center retrospective studyUnilateral total knee arthroplastyNumeric pain scoresPerioperative opioid usageCenter retrospective studyPostoperative day 1Use of glucocorticoidsLocal anesthetic adjuvantLength of stayAmount of ropivacaineRopivacaine infusionDischarge dispositionInfusion requirements
2018
Dexamethasone Injected Perineurally is More Effective than Administered Intravenously for Peripheral Nerve Blocks
Zorrilla-Vaca A, Li J. Dexamethasone Injected Perineurally is More Effective than Administered Intravenously for Peripheral Nerve Blocks. The Clinical Journal Of Pain 2018, 34: 276-284. PMID: 28591086, DOI: 10.1097/ajp.0000000000000519.Peer-Reviewed Original ResearchConceptsPeripheral nerve blocksDuration of analgesiaPerineural dexamethasoneOpioid consumptionPain scoresPostoperative nauseaSensory blockNerve blockMotor block durationPain modulation mechanismsPerioperative pain controlPreservative-free dexamethasoneBetter analgesic effectDose of dexamethasoneTerms of prolongationSubgroup of studiesRandom-effects modelIntravenous dexamethasonePain controlAnalgesic effectMotor blockPostoperative outcomesAdministered IntravenouslyIntraoperative eventsSystemic absorption