2023
Preliminary experience on systemic effects of perineural dexamethasone sodium phosphate and methylprednisolone acetate through adductor canal block in total knee arthroplasty: A single center retrospective study
Li J, Dai F, Zhou B, Cortes M, Baldev K. Preliminary experience on systemic effects of perineural dexamethasone sodium phosphate and methylprednisolone acetate through adductor canal block in total knee arthroplasty: A single center retrospective study. Journal Of Anaesthesiology Clinical Pharmacology 2023, 39: 385-391. PMID: 38025551, PMCID: PMC10661633, DOI: 10.4103/joacp.joacp_433_21.Peer-Reviewed Original ResearchWhite blood cell countAdductor canal blockTotal knee arthroplastySingle-center retrospective studyDexamethasone sodium phosphateChanges of FBGPOD 0MPA groupMethylprednisolone acetateSystemic effectsDEX groupRetrospective studyCanal blockKnee arthroplastySingle-injection adductor canal blockControl groupPOD 1Combination of glucocorticoidsDEX alone groupPreoperative baseline valuesCenter retrospective studyPostoperative day 2Local anesthetic adjuvantBlood cell countPreliminary safety data
2022
Perineural Methylprednisolone Depot Formulation Decreases Opioid Consumption After Total Knee Arthroplasty
Del Toro-Pagán NM, Dai F, Banack T, Berlin J, Makadia SA, Rubin LE, Zhou B, Huynh P, Li J. Perineural Methylprednisolone Depot Formulation Decreases Opioid Consumption After Total Knee Arthroplasty. Journal Of Pain Research 2022, 15: 2537-2546. PMID: 36061486, PMCID: PMC9432382, DOI: 10.2147/jpr.s378243.Peer-Reviewed Original ResearchWhite blood cell countTotal knee arthroplastyActive pain scoresCumulative opioid consumptionOpioid consumptionPostoperative opioid consumptionMethylprednisolone acetateMPA groupPain scoresPostoperative dayNerve blockDEX groupKnee arthroplastySingle-injection nerve blocksConsecutive TKA patientsDaily opioid consumptionPosterior knee (IPACK) blockLocal anesthetic adjuvantBlood cell countLength of stayHigher restKnee blockHospital stayTKA patientsSecondary outcomesGlucocorticoid minimizes local anesthetic infusion requirement through adductor canal block and improves perioperative prosthetic joint range of motion in total knee arthroplasty
Baldev K, Dai F, Barrett C, Zhou B, Shah M, Howie B, Boominathan P, Zhao X, Li J. Glucocorticoid minimizes local anesthetic infusion requirement through adductor canal block and improves perioperative prosthetic joint range of motion in total knee arthroplasty. PLOS ONE 2022, 17: e0261949. PMID: 35081134, PMCID: PMC8791457, DOI: 10.1371/journal.pone.0261949.Peer-Reviewed Original ResearchConceptsAdductor canal blockTotal knee arthroplastyContinuous adductor canal blockPain scoresCanal blockTreatment groupsKnee arthroplastyOpioid consumptionOpioid usageGlucocorticoid injectionSingle-injection adductor canal blockControl groupSingle-center retrospective studyUnilateral total knee arthroplastyNumeric pain scoresPerioperative opioid usageCenter retrospective studyPostoperative day 1Use of glucocorticoidsLocal anesthetic adjuvantLength of stayAmount of ropivacaineRopivacaine infusionDischarge dispositionInfusion requirements