Dexamethasone Injected Perineurally is More Effective than Administered Intravenously for Peripheral Nerve Blocks
Zorrilla-Vaca A, Li J. Dexamethasone Injected Perineurally is More Effective than Administered Intravenously for Peripheral Nerve Blocks. The Clinical Journal Of Pain 2018, 34: 276-284. PMID: 28591086, DOI: 10.1097/ajp.0000000000000519.Peer-Reviewed Original ResearchConceptsPeripheral nerve blocksDuration of analgesiaPerineural dexamethasoneOpioid consumptionPain scoresPostoperative nauseaSensory blockNerve blockMotor block durationPain modulation mechanismsPerioperative pain controlPreservative-free dexamethasoneBetter analgesic effectDose of dexamethasoneTerms of prolongationSubgroup of studiesRandom-effects modelIntravenous dexamethasonePain controlAnalgesic effectMotor blockPostoperative outcomesAdministered IntravenouslyIntraoperative eventsSystemic absorption