2020
No benefit of continuing vs stopping 5‐aminosalicylates in patients with ulcerative colitis escalated to anti‐metabolite therapy
Singh S, Kim J, Zhu W, Dulai P, Sandborn W, Jairath V. No benefit of continuing vs stopping 5‐aminosalicylates in patients with ulcerative colitis escalated to anti‐metabolite therapy. Alimentary Pharmacology & Therapeutics 2020, 52: 481-491. PMID: 32573825, PMCID: PMC8015755, DOI: 10.1111/apt.15876.Peer-Reviewed Original ResearchConceptsAnti-metabolite therapyUlcerative colitisCorticosteroid useRisk of UCCox proportional hazards analysisAdministrative claims databaseEmergency department visitsProportional hazards analysisComorbidity burdenTreatment escalationBiologic therapyAbdominal surgeryDepartment visitsClinical benefitClaims databaseResidual confoundingHigh riskPatientsDisease severityMonotherapyTherapyHospitalisationColitisSurgeryMonths
2011
Full impact of laboratory information system requires direct use by clinical staff: cluster randomized controlled trial
Blaya J, Shin S, Contreras C, Yale G, Suarez C, Asencios L, Kim J, Rodriguez P, Cegielski P, Fraser H. Full impact of laboratory information system requires direct use by clinical staff: cluster randomized controlled trial. Journal Of The American Medical Informatics Association 2011, 18: 11-16. PMID: 21113076, PMCID: PMC3005868, DOI: 10.1136/jamia.2010.005280.Peer-Reviewed Original ResearchConceptsPeripheral health centresDrug susceptibility testHealth centersIntervention groupControl groupElectronic laboratory reportingE-ChasquiCare accessClinical staffCulture resultsLaboratory reportingHealth establishmentsSusceptibility testsLaboratory information systemBaseline dataTrialsLaboratory resultsMonthsLower proportionGroupPaper-based systemProportion
2010
Electronic laboratory system reduces errors in National Tuberculosis Program: a cluster randomized controlled trial.
Blaya J, Shin S, Yale G, Suarez C, Asencios L, Contreras C, Rodriguez P, Kim J, Cegielski P, Fraser H. Electronic laboratory system reduces errors in National Tuberculosis Program: a cluster randomized controlled trial. The International Journal Of Tuberculosis And Lung Disease 2010, 14: 1009-15. PMID: 20626946, PMCID: PMC8324019.Peer-Reviewed Original ResearchConceptsControl health centersHealth centersE-ChasquiIntervention health centersNational Tuberculosis ProgrammeLaboratory information systemDrug susceptibility testTuberculosis careTuberculosis ProgrammeSusceptibility testsContinuous quality improvementBaseline dataMonthsInterventionFurther dataTrialsLaboratory resultsElectronic laboratory systemError reportsClinical usersSame monthWeeksCare