2014
Prediction of MicroRNA Precursors Using Parsimonious Feature Sets
Stepanowsky P, Levy E, Kim J, Jiang X, Ohno-Machado L. Prediction of MicroRNA Precursors Using Parsimonious Feature Sets. Cancer Informatics 2014, 13s1: cin.s13877. PMID: 25392687, PMCID: PMC4216048, DOI: 10.4137/cin.s13877.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2013
Differential Expression of miR-145 in Children with Kawasaki Disease
Shimizu C, Kim J, Stepanowsky P, Trinh C, Lau H, Akers J, Chen C, Kanegaye J, Tremoulet A, Ohno-Machado L, Burns J. Differential Expression of miR-145 in Children with Kawasaki Disease. PLOS ONE 2013, 8: e58159. PMID: 23483985, PMCID: PMC3590129, DOI: 10.1371/journal.pone.0058159.Peer-Reviewed Original ResearchMeSH KeywordsArteriesBase SequenceChildChild, PreschoolCluster AnalysisGene Expression RegulationHumansInfantMicroRNAsModels, BiologicalMolecular Sequence DataMucocutaneous Lymph Node SyndromeReal-Time Polymerase Chain ReactionSequence AlignmentSequence Analysis, DNASignal TransductionTransforming Growth Factor betaConceptsTGF-β pathwayGene expressionMiR-145Small non-coding RNAsKawasaki disease pathogenesisExtracellular vesiclesSmall RNA speciesPost-transcriptional levelDiscovery of microRNAsKawasaki diseaseNon-coding RNAsExpression of genesDisease pathogenesisSmall extracellular vesiclesSmall RNAsRNA speciesTarget genesTop pathwaysVascular smooth muscle cellsPathway analysisDifferentiation of neutrophilsDifferential expressionMicroRNAsArterial wallGeneration of myofibroblasts
2011
Microarray profiling reveals the integrated stress response is activated by halofuginone in mammary epithelial cells
Kamberov Y, Kim J, Mazitschek R, Kuo W, Whitman M. Microarray profiling reveals the integrated stress response is activated by halofuginone in mammary epithelial cells. BMC Research Notes 2011, 4: 381. PMID: 21974968, PMCID: PMC3197508, DOI: 10.1186/1756-0500-4-381.Peer-Reviewed Original ResearchIntegrated stress responseStress responseExtracellular matrix gene expressionGlobal expression profilesEpithelial cellsMicroarray expression analysisMatrix gene expressionMammary epithelial cellsTranscriptional controlTranscriptional responseExpression analysisGene expressionExpression profilesMicroarray profilingTGFβ signalingCell differentiationCell typesECM componentsPotent regulatorAmelioration of fibrosisTh17 cell differentiationSignal inhibitionCommon mechanismEffect of halofuginoneBiological effects