Microarray profiling reveals the integrated stress response is activated by halofuginone in mammary epithelial cells
Kamberov Y, Kim J, Mazitschek R, Kuo W, Whitman M. Microarray profiling reveals the integrated stress response is activated by halofuginone in mammary epithelial cells. BMC Research Notes 2011, 4: 381. PMID: 21974968, PMCID: PMC3197508, DOI: 10.1186/1756-0500-4-381.Peer-Reviewed Original ResearchIntegrated stress responseStress responseExtracellular matrix gene expressionGlobal expression profilesEpithelial cellsMicroarray expression analysisMatrix gene expressionMammary epithelial cellsTranscriptional controlTranscriptional responseExpression analysisGene expressionExpression profilesMicroarray profilingTGFβ signalingCell differentiationCell typesECM componentsPotent regulatorAmelioration of fibrosisTh17 cell differentiationSignal inhibitionCommon mechanismEffect of halofuginoneBiological effects