2020
Genetically Determined Omega-3 Polyunsaturated Fatty Acids and Lung Function: A Mendelian Randomization Analysis
Patchen B, Xu J, Hancock D, Cassano P. Genetically Determined Omega-3 Polyunsaturated Fatty Acids and Lung Function: A Mendelian Randomization Analysis. Current Developments In Nutrition 2020, 4: nzaa061_101. PMCID: PMC7259102, DOI: 10.1093/cdn/nzaa061_101.Peer-Reviewed Original ResearchAssociated with FEV1Multivariable MRMendelian randomizationForced vital capacityHeart and Aging ResearchInverse variance weighted methodHealth training programsMendelian randomization analysisVariance weighted methodGenome-wide association dataImprove causal inferenceCross-sectional studyLung functionNational InstituteWald ratioDigestive and Kidney DiseasesSample MRUnivariable MREpidemiology ConsortiumUK BiobankResidual confoundingNational Institute of DiabetesRandomization analysisTraining programForced expiratory volume
2019
Positive Associations of Dietary Marine Omega-3 Polyunsaturated Fatty Acids with Lung Function: A Meta-analysis (P18-087-19)
Patchen B, Xu J, Barr R, van Eekelen E, Dupuis J, North K, Gharib S, Lahousse L, Lemaitre R, Manichaikul A, de Mutsert R, Houston D, Saccone N, Steffen L, Terzikhan N, Xu H, Wojczynski M, Hancock D, Cassano P. Positive Associations of Dietary Marine Omega-3 Polyunsaturated Fatty Acids with Lung Function: A Meta-analysis (P18-087-19). Current Developments In Nutrition 2019, 3: nzz039.p18-087-19. PMCID: PMC6579416, DOI: 10.1093/cdn/nzz039.p18-087-19.Peer-Reviewed Original ResearchForced vital capacityN-3 PUFAFormer smokersLung functionHeart and Aging ResearchMeta-analysisAlpha-linolenic acidDietary intakeFish intakeGenomic Epidemiology ConsortiumFixed-effect meta-analysisPositive associationAssociated with forced expiratory volumeAssociated with higher lung functionHigher forced vital capacityDocosahexaenoic acidSD higher intakeAssociated with FEV1Higher lung functionDocosapentaenoic acidEicosapentanoic acidMarine n-3 PUFADietary n-3 PUFASmoking status interactionAssociation of docosahexaenoic acid
2017
Dietary Patterns and Lung Function: Assessment of the Alternative Health Eating Index‐2010 (AHEI‐2010) and Rate of Change in Forced Expiratory Volume in the First Second (FEV 1 )
Rettig S, Xu J, Karr A, Tang W, Guertin K, Goodman P, Minasian L, Lippman S, Klein E, Cassano P. Dietary Patterns and Lung Function: Assessment of the Alternative Health Eating Index‐2010 (AHEI‐2010) and Rate of Change in Forced Expiratory Volume in the First Second (FEV 1 ). The FASEB Journal 2017, 31 DOI: 10.1096/fasebj.31.1_supplement.167.8.Peer-Reviewed Original ResearchAHEI-2010 scoreFood frequency questionnaireAHEI-2010US Dietary GuidelinesNever/former smokersDietary guidelinesRate of declineAlternative Healthy Eating Index-2010Dietary patternsMeasure of overall dietary qualitySmoking statusHealthy Eating Index-2010Assess usual dietary intakesDietary intakeOverall dietary qualityForced expiratory volumeFEV 1Lung functionUsual dietary intakeStudies of dietStatistically significant interactionExpiratory volumeDietary qualityFrequency questionnaireLinear mixed-effects models