Activation of locus coeruleus neurons by peripheral stimuli: Modulation by a collateral inhibitory mechanism
Cedarbaum J, Aghajanian G. Activation of locus coeruleus neurons by peripheral stimuli: Modulation by a collateral inhibitory mechanism. Life Sciences 1978, 23: 1383-1392. PMID: 214648, DOI: 10.1016/0024-3205(78)90398-3.Peer-Reviewed Original ResearchConceptsLocus coeruleusNerve stimulationLocus coeruleus neuronsRat locus coeruleusPeripheral nerve stimulationBursts of spikesNeuronal responsivityNoradrenergic neuronsCoeruleus neuronsAntidromic activationAxon collateralsAdrenergic antagonistsPutative transmittersNoxious stimuliPeripheral stimuliUnit firingReduced responsivityAutoinhibitory actionInhibitory mechanismPiperoxaneNeuronsAdditional stimulusStimulationCollateralsStimuli