2023
Watchman device migration and embolization: A report from the NCDR LAAO Registry
Friedman D, Freeman J, Zimmerman S, Tan Z, Pereira L, Faridi K, Curtis J. Watchman device migration and embolization: A report from the NCDR LAAO Registry. Journal Of Cardiovascular Electrophysiology 2023, 34: 1192-1195. PMID: 37078339, PMCID: PMC10290479, DOI: 10.1111/jce.15909.Peer-Reviewed Original ResearchConceptsWATCHMAN procedureSurgical retrievalDevice migrationMortality rateAtrial appendage closure deviceHospital mortality rateAnnual procedure volumeCardiac surgeryHospital eventsPostdischarge eventsOstial sizeDevice embolizationTaller patientsRetrospective analysisClosure deviceLAA ostiumPatientsProcedure volumeHigh mortalitySurgerySubstantial proportionEmbolizationRegistryGreater body massBody mass
2022
Development and validation of an automated algorithm for end point adjudication for a large U.S. national registry
Friedman DJ, Pierre D, Wang Y, Gambone L, Koutras C, Segawa C, Farb A, Vemulapalli S, Varosy PD, Masoudi FA, Lansky A, Curtis JP, Freeman JV. Development and validation of an automated algorithm for end point adjudication for a large U.S. national registry. American Heart Journal 2022, 254: 102-111. PMID: 36007567, DOI: 10.1016/j.ahj.2022.08.006.Peer-Reviewed Original ResearchMeSH KeywordsAftercareAtrial AppendageAtrial FibrillationHumansIschemic Attack, TransientPatient DischargeRegistriesStrokeTreatment OutcomeConceptsEnd point adjudicationCEC adjudicationEnd pointLarge registriesClinical trialsNational Cardiovascular Data RegistryMajor vascular complicationsU.S. National RegistryPost-discharge eventsAgreement rateMajor bleedingNeurologic eventsVascular complicationsNational registryEvent adjudicationData registryRegistryCommittee's evaluationsPercent agreementGold standardAgreement thresholdHospitalTrialsFurther confirmationBleedingPeriprocedural Pericardial Effusion Complicating Transcatheter Left Atrial Appendage Occlusion: A Report From the NCDR LAAO Registry
Price MJ, Valderrábano M, Zimmerman S, Friedman DJ, Kar S, Curtis JP, Masoudi FA, Freeman JV. Periprocedural Pericardial Effusion Complicating Transcatheter Left Atrial Appendage Occlusion: A Report From the NCDR LAAO Registry. Circulation Cardiovascular Interventions 2022, 15: e011718. PMID: 35369701, PMCID: PMC9132377, DOI: 10.1161/circinterventions.121.011718.Peer-Reviewed Original ResearchConceptsAtrial appendage occlusionComposite of deathPericardial effusionAppendage occlusionSystemic embolismOdds ratioEarly postdischarge mortalityDual antiplatelet therapyLow serum albuminMean patient ageAdverse event ratesParoxysmal atrial fibrillationRisk of deathRisk-benefit ratioHospital strokeMean CHAPostdischarge mortalityVASc scoreWATCHMAN procedureAntiplatelet therapyIndex hospitalizationAdverse eventsPatient agePrimary outcomeVentricular function
2020
Revascularization Practices and Outcomes in Patients With Multivessel Coronary Artery Disease Who Presented With Acute Myocardial Infarction and Cardiogenic Shock in the US, 2009-2018
Khera R, Secemsky EA, Wang Y, Desai NR, Krumholz HM, Maddox TM, Shunk KA, Virani SS, Bhatt DL, Curtis J, Yeh RW. Revascularization Practices and Outcomes in Patients With Multivessel Coronary Artery Disease Who Presented With Acute Myocardial Infarction and Cardiogenic Shock in the US, 2009-2018. JAMA Internal Medicine 2020, 180: 1317-1327. PMID: 32833024, PMCID: PMC9377424, DOI: 10.1001/jamainternmed.2020.3276.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCohort StudiesCoronary VesselsFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedMyocardial InfarctionPatient DischargePercutaneous Coronary InterventionRisk AssessmentRisk FactorsShock, CardiogenicST Elevation Myocardial InfarctionTime FactorsTreatment OutcomeUnited StatesConceptsST-segment elevation myocardial infarctionMultivessel percutaneous coronary interventionMultivessel coronary artery diseasePercutaneous coronary interventionAcute myocardial infarctionCoronary artery diseaseCulprit vessel percutaneous coronary interventionCardiogenic shockHospital mortalityArtery diseaseMyocardial infarctionCohort studyPrimary outcomeHospital variationPCI strategyMedicare beneficiariesUnderwent multivessel PCISignificant hospital variationElevation myocardial infarctionSubset of patientsHigh-risk populationRecent evidenceHospital complicationsPCI useRevascularization practice
2018
Predicting Length of Stay and the Need for Postacute Care After Acute Myocardial Infarction to Improve Healthcare Efficiency
Wasfy JH, Kennedy KF, Masoudi FA, Ferris TG, Arnold SV, Kini V, Peterson P, Curtis JP, Amin AP, Bradley SM, French WJ, Messenger J, Ho PM, Spertus JA. Predicting Length of Stay and the Need for Postacute Care After Acute Myocardial Infarction to Improve Healthcare Efficiency. Circulation Cardiovascular Quality And Outcomes 2018, 11: e004635. PMID: 30354547, PMCID: PMC6207219, DOI: 10.1161/circoutcomes.118.004635.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overClinical Decision-MakingDecision Support TechniquesDelivery of Health Care, IntegratedEfficiency, OrganizationalFemaleHumansLength of StayMaleMiddle AgedMyocardial InfarctionPatient DischargePredictive Value of TestsQuality ImprovementQuality Indicators, Health CareRegistriesRisk FactorsSubacute CareTime FactorsTreatment OutcomeUnited StatesConceptsLength of stayAcute myocardial infarctionAcute MI patientsMyocardial infarctionPostacute carePostacute facilitiesMI patientsST-segment elevation myocardial infarctionPostacute care facilityCare of patientsHierarchical logistic regression modelsLogistic regression modelsCoordinated care planningInitial hospitalizationHospital admissionACTION RegistryTraining cohortCare coordinationNational registryMI subgroupCare planningCare facilitiesPatientsProspective testingHospitalization
2017
Hospital Performance on Percutaneous Coronary Intervention Process and Outcomes Measures
Chui PW, Parzynski CS, Nallamothu BK, Masoudi FA, Krumholz HM, Curtis JP. Hospital Performance on Percutaneous Coronary Intervention Process and Outcomes Measures. Journal Of The American Heart Association 2017, 6: e004276. PMID: 28446493, PMCID: PMC5524055, DOI: 10.1161/jaha.116.004276.Peer-Reviewed Original ResearchMeSH KeywordsCardiac RehabilitationCoronary DiseaseCross-Sectional StudiesHealthcare DisparitiesHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMedicarePatient DischargePatient ReadmissionPercutaneous Coronary InterventionPlatelet Aggregation InhibitorsProcess Assessment, Health CareQuality ImprovementQuality Indicators, Health CareReferral and ConsultationRegistriesRisk FactorsTime FactorsTime-to-TreatmentTreatment OutcomeUnited StatesConceptsProcess measuresReadmission ratesOutcome measuresNational Cardiovascular Data Registry CathPCI RegistryHospital performancePercutaneous coronary interventionSpecific process measuresRisk-standardized mortalityPCI patientsCathPCI RegistryCoronary interventionHospital variationOutcome ratesHospital qualityPhysician ConsortiumMortalitySmall percentageWeak correlationAssociationIntervention processPatients
2015
National Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010)
Minges KE, Bikdeli B, Wang Y, Kim N, Curtis JP, Desai MM, Krumholz HM. National Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010). The American Journal Of Cardiology 2015, 116: 1436-1442. PMID: 26409636, PMCID: PMC4841688, DOI: 10.1016/j.amjcard.2015.07.068.Peer-Reviewed Original ResearchConceptsHospitalization ratesMortality rateReadmission ratesBlack patientsPrincipal discharge diagnosis codeOlder adultsCause readmission rateHospital mortality rateProportion of patientsRetrospective cohort studyDischarge diagnosis codesSkilled nursing facilitiesNational trendsSignificant racial differencesHigh rateHome health careHospital stayAdults AgedCohort studyMore patientsTherapeutic advancesDiagnosis codesMedicare feeNursing facilitiesSignificant burdenAntithrombotic Therapy and Outcomes After ICD Implantation in Patients With Atrial Fibrillation and Coronary Artery Disease: An Analysis From the National Cardiovascular Data Registry (NCDR)®
Ghanbari H, Nallamothu BK, Wang Y, Curtis JP. Antithrombotic Therapy and Outcomes After ICD Implantation in Patients With Atrial Fibrillation and Coronary Artery Disease: An Analysis From the National Cardiovascular Data Registry (NCDR)®. Journal Of The American Heart Association 2015, 4: e001331. PMID: 25637345, PMCID: PMC4345865, DOI: 10.1161/jaha.114.001331.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrial FibrillationCoronary Artery DiseaseDefibrillators, ImplantableDrug Therapy, CombinationFemaleFibrinolytic AgentsHemorrhageHumansIncidenceMaleMedicareMiddle AgedPatient DischargePlatelet Aggregation InhibitorsRegistriesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesWarfarinConceptsImplantable cardioverter defibrillator implantationCardioverter-defibrillator implantationCoronary artery diseaseMajor adverse cardiovascular eventsNational Cardiovascular Data RegistryAdverse cardiovascular eventsDevice-related complicationsAntithrombotic agentsDefibrillator implantationArtery diseaseAtrial fibrillationAntithrombotic therapyBleeding riskCardiovascular eventsThromboembolic eventsNational Cardiovascular Data Registry Implantable Cardioverter Defibrillator RegistryImplantable Cardioverter-Defibrillator RegistryHigh bleeding riskCombination of DAHospital dischargeICD implantationPrimary outcomeData registryPatientsFibrillation
2013
Prevalence, Correlates, and Temporal Trends in Antiarrhythmic Drug Use at Discharge After Implantable Cardioverter Defibrillator Placement (from the National Cardiovascular Data Registry [NCDR])
Dev S, Peterson PN, Wang Y, Curtis JP, Varosy PD, Masoudi FA. Prevalence, Correlates, and Temporal Trends in Antiarrhythmic Drug Use at Discharge After Implantable Cardioverter Defibrillator Placement (from the National Cardiovascular Data Registry [NCDR]). The American Journal Of Cardiology 2013, 113: 314-320. PMID: 24216126, DOI: 10.1016/j.amjcard.2013.09.023.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillatorAntiarrhythmic drug useAntiarrhythmic drugsMedian odds ratioHospital dischargeOdds ratioSecondary prevention implantable cardioverter defibrillatorDrug useClass III antiarrhythmic drugsImplantable cardioverter-defibrillator placementMultivariate logistic regression modelHospital-level variationClass III agentsLocal treatment patternsLogistic regression modelsFacility-level variablesAntiarrhythmic useICD implantationICD recipientsICD RegistryHospital variationICD placementTreatment patternsDevice shocksAntiarrhythmic agents
2010
Trends in Length of Stay and Short-term Outcomes Among Medicare Patients Hospitalized for Heart Failure, 1993-2006
Bueno H, Ross JS, Wang Y, Chen J, Vidán MT, Normand SL, Curtis JP, Drye EE, Lichtman JH, Keenan PS, Kosiborod M, Krumholz HM. Trends in Length of Stay and Short-term Outcomes Among Medicare Patients Hospitalized for Heart Failure, 1993-2006. JAMA 2010, 303: 2141-2147. PMID: 20516414, PMCID: PMC3020983, DOI: 10.1001/jama.2010.748.Peer-Reviewed Original ResearchConceptsLength of stayShort-term outcomesHeart failureReadmission ratesHospital mortalityDischarge dispositionRisk ratioThirty-day readmission ratesMortality risk ratioSkilled nursing facilitiesHome care servicesHospital stayOlder patientsUnadjusted analysesMedicare patientsObservational studyMedicare feeNursing facilitiesPatientsStayCare servicesMortalityMarked reductionMean lengthOutcomes
2004
National Patterns of Use and Effectiveness of Angiotensin-Converting Enzyme Inhibitors in Older Patients With Heart Failure and Left Ventricular Systolic Dysfunction
Masoudi FA, Rathore SS, Wang Y, Havranek EP, Curtis JP, Foody JM, Krumholz HM. National Patterns of Use and Effectiveness of Angiotensin-Converting Enzyme Inhibitors in Older Patients With Heart Failure and Left Ventricular Systolic Dysfunction. Circulation 2004, 110: 724-731. PMID: 15289383, DOI: 10.1161/01.cir.0000138934.28340.ed.Peer-Reviewed Original ResearchConceptsACE inhibitor prescriptionAngiotensin receptor blockersVentricular systolic dysfunctionHeart failureACE inhibitorsInhibitor prescriptionSystolic dysfunctionOlder patientsLeft ventricular systolic dysfunctionAngiotensin converting enzyme (ACE) inhibitorsSerum creatinine levelsACE inhibitor useCreatinine levelsHospital factorsInhibitor useReceptor blockersSerum creatininePatient genderClinical trialsTherapeutic substitutionLower riskEnzyme inhibitorsLower mortalityPatientsSecondary analysisAssociation Between Functional Status and Use and Effectiveness of Beta‐Blocker Prophylaxis in Elderly Survivors of Acute Myocardial Infarction
Vitagliano G, Curtis JP, Concato J, Feinstein AR, Radford MJ, Krumholz HM. Association Between Functional Status and Use and Effectiveness of Beta‐Blocker Prophylaxis in Elderly Survivors of Acute Myocardial Infarction. Journal Of The American Geriatrics Society 2004, 52: 495-501. PMID: 15066062, DOI: 10.1111/j.1532-5415.2004.52153.x.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAcute DiseaseAdrenergic beta-AntagonistsAge FactorsAgedAged, 80 and overCross-Sectional StudiesDrug PrescriptionsDrug UtilizationFemaleGeriatric AssessmentHumansLogistic ModelsMaleMultivariate AnalysisMyocardial InfarctionPatient DischargePatient SelectionPractice Patterns, Physicians'Proportional Hazards ModelsRetrospective StudiesSurvival AnalysisTreatment OutcomeUnited StatesConceptsAcute myocardial infarctionHospital dischargeFunctional impairmentElderly patientsMyocardial infarctionAcute myocardial infarction survivorsBeta-blocker prescriptionBeta-blocker prophylaxisBeta-blocker treatmentRetrospective cohort studySimilar survival benefitMain outcome measuresMyocardial infarction survivorsAcute care hospitalsEligible patientsCohort studySurvival benefitCare hospitalFunctional statusNational cohortInfarction survivorsOutcome measuresElderly survivorsPatientsCognitive impairment
2003
Aspirin, ibuprofen, and mortality after myocardial infarction: retrospective cohort study
Curtis JP, Wang Y, Portnay EL, Masoudi FA, Havranek EP, Krumholz HM. Aspirin, ibuprofen, and mortality after myocardial infarction: retrospective cohort study. The BMJ 2003, 327: 1322. PMID: 14656840, PMCID: PMC286319, DOI: 10.1136/bmj.327.7427.1322.Peer-Reviewed Original Research