2022
Periprocedural Pericardial Effusion Complicating Transcatheter Left Atrial Appendage Occlusion: A Report From the NCDR LAAO Registry
Price MJ, Valderrábano M, Zimmerman S, Friedman DJ, Kar S, Curtis JP, Masoudi FA, Freeman JV. Periprocedural Pericardial Effusion Complicating Transcatheter Left Atrial Appendage Occlusion: A Report From the NCDR LAAO Registry. Circulation Cardiovascular Interventions 2022, 15: e011718. PMID: 35369701, PMCID: PMC9132377, DOI: 10.1161/circinterventions.121.011718.Peer-Reviewed Original ResearchConceptsAtrial appendage occlusionComposite of deathPericardial effusionAppendage occlusionSystemic embolismOdds ratioEarly postdischarge mortalityDual antiplatelet therapyLow serum albuminMean patient ageAdverse event ratesParoxysmal atrial fibrillationRisk of deathRisk-benefit ratioHospital strokeMean CHAPostdischarge mortalityVASc scoreWATCHMAN procedureAntiplatelet therapyIndex hospitalizationAdverse eventsPatient agePrimary outcomeVentricular functionTrends in Use of Single- vs Dual-Chamber Implantable Cardioverter-Defibrillators Among Patients Without a Pacing Indication, 2010-2018
Borne RT, Varosy P, Lan Z, Masoudi FA, Curtis JP, Matlock DD, Peterson PN. Trends in Use of Single- vs Dual-Chamber Implantable Cardioverter-Defibrillators Among Patients Without a Pacing Indication, 2010-2018. JAMA Network Open 2022, 5: e223429. PMID: 35315917, PMCID: PMC8941353, DOI: 10.1001/jamanetworkopen.2022.3429.Peer-Reviewed Original ResearchConceptsDual-chamber ICDFirst-time ICD implantationPacing indicationICD implantationMedian odds ratioPatient characteristicsOdds ratioAtrial leadNational Cardiovascular Data Registry ICD RegistryCardiac resynchronization therapy indicationDual-chamber ICD implantationMulticenter cross-sectional studyBradycardia pacing indicationSingle-chamber ICDHospital-level variationHigh procedural riskCross-sectional studyLow-value practicesImplantable cardioverter defibrillatorLow-value careCochran-Armitage trend testImplantable cardioverter-defibrillator systemsDual-chamber devicesCardioverter-defibrillator systemsReal-world practice
2019
The Evolving Landscape of Impella® Use in the United States Among Patients Undergoing Percutaneous Coronary Intervention with Mechanical Circulatory Support
Amin AP, Spertus JA, Curtis JP, Desai N, Masoudi FA, Bach RG, McNeely C, Al-Badarin F, House JA, Kulkarni H, Rao SV. The Evolving Landscape of Impella® Use in the United States Among Patients Undergoing Percutaneous Coronary Intervention with Mechanical Circulatory Support. Circulation 2019, 141: 273-284. PMID: 31735078, DOI: 10.1161/circulationaha.119.044007.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionMechanical circulatory supportAcute kidney injuryImpella useOdds ratioKidney injuryCoronary interventionClinical outcomesCirculatory supportAdverse outcomesPremier Healthcare DatabaseClustering of patientsHigh rateAdverse eventsPatient levelImpellaPropensity adjustmentHospital levelHealthcare databasesPatientsUS hospitalsHospitalPropensity scoreAssociated outcomesWide variationAnalysis of Temporal Trends and Variation in the Use of Defibrillation Testing in Contemporary Practice
Borne RT, Randolph T, Wang Y, Curtis JP, Peterson PN, Masoudi FA, Sandhu A, Zipse MM, Thomas K, Kutyifa V, Desai NR, Cha YM, Hsu JC, Russo AM. Analysis of Temporal Trends and Variation in the Use of Defibrillation Testing in Contemporary Practice. JAMA Network Open 2019, 2: e1913553. PMID: 31626314, PMCID: PMC6813586, DOI: 10.1001/jamanetworkopen.2019.13553.Peer-Reviewed Original ResearchConceptsNational Cardiovascular Data Registry ICD RegistryMedian odds ratioDefibrillation testingLow testing ratesTesting ratesHigher testing ratesICD RegistryFirst-time ICD implantationImplantable cardioverter defibrillator implantationMulticenter cross-sectional studyAdvanced heart failureCardioverter-defibrillator implantationIschemic heart diseaseCross-sectional studyICD implantationHeart failureICD placementVentricular arrhythmiasMean ageHeart diseaseVentricular tachycardiaOdds ratioHigher oddsMAIN OUTCOMEFirst calendar quarter
2015
Hospital Variability in Use of Anticoagulant Strategies During Acute Myocardial Infarction Treated With an Early Invasive Strategy
Arnold SV, Li SX, Alexander KP, Spertus JA, Nallamothu BK, Curtis JP, Kosiborod M, Gupta A, Wang TY, Lin H, Dharmarajan K, Strait KM, Lowe TJ, Krumholz HM. Hospital Variability in Use of Anticoagulant Strategies During Acute Myocardial Infarction Treated With an Early Invasive Strategy. Journal Of The American Heart Association 2015, 4: e002009. PMID: 26077589, PMCID: PMC4599539, DOI: 10.1161/jaha.115.002009.Peer-Reviewed Original ResearchConceptsEarly invasive strategyAnticoagulant strategiesMyocardial infarctionBleeding rateInvasive strategyAcute myocardial infarction patientsOptimal anticoagulant strategyHalf of patientsPercutaneous coronary interventionAcute myocardial infarctionMyocardial infarction patientsHospital use patternsComparative effectiveness studiesRisk-standardized mortalityChoice of anticoagulantsMedian odds ratioCoronary interventionPatient factorsSystemic anticoagulationHospital variabilityInfarction patientsPrincipal diagnosisOdds ratioMultivariate regression modelPatterns of use
2014
In-Hospital Complications Associated With Reoperations of Implantable Cardioverter Defibrillators
Steckman DA, Varosy PD, Parzynski CS, Masoudi FA, Curtis JP, Sauer WH, Nguyen DT. In-Hospital Complications Associated With Reoperations of Implantable Cardioverter Defibrillators. The American Journal Of Cardiology 2014, 114: 419-426. PMID: 24927972, DOI: 10.1016/j.amjcard.2014.05.010.Peer-Reviewed Original ResearchConceptsHospital complicationsComplication rateRepeat proceduresLead extractionICD proceduresMultivariable adjusted odds ratiosNational Cardiovascular Data RegistryInitial implantImplantable cardioverter-defibrillator (ICD) proceduresHierarchical multivariable logistic regressionHospital adverse eventsAdjusted odds ratioHigh complication rateMultivariable logistic regressionLarge national cohortImplantable cardioverter defibrillatorHospital deathAdverse eventsICD implantationPatient characteristicsNational cohortOdds ratioProcedural outcomesCardioverter defibrillatorHigh risk
2013
Prevalence, Correlates, and Temporal Trends in Antiarrhythmic Drug Use at Discharge After Implantable Cardioverter Defibrillator Placement (from the National Cardiovascular Data Registry [NCDR])
Dev S, Peterson PN, Wang Y, Curtis JP, Varosy PD, Masoudi FA. Prevalence, Correlates, and Temporal Trends in Antiarrhythmic Drug Use at Discharge After Implantable Cardioverter Defibrillator Placement (from the National Cardiovascular Data Registry [NCDR]). The American Journal Of Cardiology 2013, 113: 314-320. PMID: 24216126, DOI: 10.1016/j.amjcard.2013.09.023.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillatorAntiarrhythmic drug useAntiarrhythmic drugsMedian odds ratioHospital dischargeOdds ratioSecondary prevention implantable cardioverter defibrillatorDrug useClass III antiarrhythmic drugsImplantable cardioverter-defibrillator placementMultivariate logistic regression modelHospital-level variationClass III agentsLocal treatment patternsLogistic regression modelsFacility-level variablesAntiarrhythmic useICD implantationICD recipientsICD RegistryHospital variationICD placementTreatment patternsDevice shocksAntiarrhythmic agentsUse of Remote Monitoring of Newly Implanted Cardioverter-Defibrillators
Akar JG, Bao H, Jones P, Wang Y, Chaudhry SI, Varosy P, Masoudi FA, Stein K, Saxon LA, Curtis JP. Use of Remote Monitoring of Newly Implanted Cardioverter-Defibrillators. Circulation 2013, 128: 2372-2383. PMID: 24043302, DOI: 10.1161/circulationaha.113.002481.Peer-Reviewed Original ResearchConceptsMedian odds ratioOdds ratioNational Cardiovascular Data Registry ICD RegistryRemote patient monitoringMultivariable logistic regressionHealth-related factorsImplanted cardioverter defibrillatorEligible patientsICD RegistryLack of enrollmentCurrent guidelinesCardioverter defibrillatorPatientsLogistic regressionLocal practice environmentMajor causeHealth insuranceSubsequent activationEnrollmentPractice environmentPatient monitoringPhysiciansActivationRPM systemSuccessful use
2007
Impact of Delay in Door-to-Needle Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction
McNamara RL, Herrin J, Wang Y, Curtis JP, Bradley EH, Magid DJ, Rathore SS, Nallamothu BK, Peterson ED, Blaney ME, Frederick P, Krumholz HM. Impact of Delay in Door-to-Needle Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction. The American Journal Of Cardiology 2007, 100: 1227-1232. PMID: 17920362, PMCID: PMC2715362, DOI: 10.1016/j.amjcard.2007.05.043.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArrhythmias, CardiacCaliforniaCohort StudiesEmergency Service, HospitalEmergency TreatmentFemaleFibrinolytic AgentsHospital MortalityHumansMaleMedical RecordsMyocardial InfarctionOutcome Assessment, Health CareRegistriesRetrospective StudiesThrombolytic TherapyTime and Motion StudiesTime FactorsConceptsST-segment elevation myocardial infarctionElevation myocardial infarctionNeedle timeFibrinolytic therapyMyocardial infarctionHospital mortalitySymptom onsetOdds ratioReperfusion strategyAdjunctive medicationsHospital arrivalShorter doorTimely administrationNational registryRepresentative cohortPatientsMortalityInfarctionTherapyIndependent effectsCohortMinutesSmaller centersOnsetImpact of delay