2021
Sex Differences in Procedural Outcomes Among Patients Undergoing Left Atrial Appendage Occlusion
Darden D, Duong T, Du C, Munir MB, Han FT, Reeves R, Saw J, Zeitler EP, Al-Khatib SM, Russo AM, Minges KE, Curtis JP, Freeman JV, Hsu JC. Sex Differences in Procedural Outcomes Among Patients Undergoing Left Atrial Appendage Occlusion. JAMA Cardiology 2021, 6: 1275-1284. PMID: 34379072, PMCID: PMC8358791, DOI: 10.1001/jamacardio.2021.3021.Peer-Reviewed Original ResearchConceptsHospital adverse eventsMajor adverse eventsAdverse eventsAtrial appendage occlusionMajor bleedingPericardial effusionAppendage occlusionAtrial fibrillationSex differencesCongestive heart failureCoronary artery diseaseAdjusted logistic regression analysisParoxysmal atrial fibrillationLogistic regression analysisMultivariable adjusted logistic regression analysesPrior strokeUncontrolled hypertensionHospital outcomesHospital stayMultivariable adjustmentProlonged hospitalBaseline characteristicsCohort studySelect patientsArtery diseaseDefibrillation Safety Margin Testing in Patients With Congenital Heart Disease Results From the NCDR
Prutkin JM, Wang Y, Escudero CA, Stephenson EA, Minges KE, Curtis JP, Hsu JC. Defibrillation Safety Margin Testing in Patients With Congenital Heart Disease Results From the NCDR. JACC Clinical Electrophysiology 2021, 7: 1145-1154. PMID: 33933411, DOI: 10.1016/j.jacep.2021.02.019.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseLowest successful energyHospital stayNational Cardiovascular Data Registry ICD RegistryImplantable cardioverter-defibrillator insertionVentricular septal defectTetralogy of FallotHeart disease resultHospital complicationsHospital deathHospital outcomesMultivariable adjustmentEbstein's anomalyICD RegistryICD recipientsSeptal defectCommon ventricleHeart diseaseRetrospective analysisLower oddsGreat vesselsICD proceduresDisease resultsSuccessful energyICD generator
2020
Trends in Use and In-Hospital Outcomes of Subcutaneous Implantable Cardioverter Defibrillators in Patients Undergoing Long-Term Dialysis
Pun PH, Parzynski CS, Friedman DJ, Sanders G, Curtis JP, Al-Khatib SM. Trends in Use and In-Hospital Outcomes of Subcutaneous Implantable Cardioverter Defibrillators in Patients Undergoing Long-Term Dialysis. Clinical Journal Of The American Society Of Nephrology 2020, 15: 1622-1630. PMID: 32967922, PMCID: PMC7646229, DOI: 10.2215/cjn.07920520.Peer-Reviewed Original ResearchConceptsHospital cardiac arrestSubcutaneous ICDTransvenous ICDICD implantsHospital outcomesICD recipientsICD RegistryCardiac arrestHigh riskNational Cardiovascular Data Registry ICD RegistryFirst-time ICD recipientsPropensity score-weighted analysisImplantable cardioverter defibrillator implantationSubcutaneous implantable cardioverter defibrillatorIn-Hospital OutcomesShort-term complicationsCardioverter-defibrillator implantationLong-term dialysisVascular access siteImplantable cardioverter defibrillatorCause deathHospital complicationsHospital stayDefibrillator implantationUS patientsPrevalence, predictors and complications with defibrillation threshold testing in pediatric patients: Results from the NCDR
Prutkin JM, Wang Y, Escudero CA, Stephenson EA, Minges KE, Curtis JP, Hsu JC. Prevalence, predictors and complications with defibrillation threshold testing in pediatric patients: Results from the NCDR. International Journal Of Cardiology 2020, 305: 44-49. PMID: 31980272, DOI: 10.1016/j.ijcard.2020.01.027.Peer-Reviewed Original ResearchConceptsInadequate defibrillation safety marginDefibrillation safety marginDFT testingDefibrillation threshold testingHospital complicationsPediatric patientsHospital stayICD recipientsNational Cardiovascular Data Registry ICD RegistryThreshold testingLowest successful energyProlonged hospital stayRisk of complicationsTransvenous ICD implantationHospital dischargeICD implantationMultivariable adjustmentICD RegistryPediatric populationRetrospective analysisLower oddsComplicationsPatientsTesting useLittle data
2017
Coronary Venous Dissection from Left Ventricular Lead Placement During Cardiac Resynchronization Therapy With Defibrillator Implantation and Associated in-Hospital Adverse Events (from the NCDR ICD Registry)
Hsu JC, Varosy PD, Bao H, Dewland TA, Curtis JP, Marcus GM. Coronary Venous Dissection from Left Ventricular Lead Placement During Cardiac Resynchronization Therapy With Defibrillator Implantation and Associated in-Hospital Adverse Events (from the NCDR ICD Registry). The American Journal Of Cardiology 2017, 121: 55-61. PMID: 29102348, DOI: 10.1016/j.amjcard.2017.09.019.Peer-Reviewed Original ResearchConceptsCRT-D recipientsVentricular lead placementHospital adverse eventsVenous dissectionMultivariable adjustmentAdverse eventsMajor complicationsLead placementGreater oddsPrevious coronary artery bypass graftImplantable Cardioverter-Defibrillator RegistryLeft ventricular lead placementCoronary artery bypass graftHierarchical multivariable logistic regressionHospital clinical outcomesArtery bypass graftCardiac resynchronization therapyMultivariable logistic regressionBundle branch blockHospital complicationsHospital mortalityHospital deathHospital stayDefibrillator implantationProlonged hospitalization
2016
Temporal Trends in the Risk Profile of Patients Undergoing Outpatient Percutaneous Coronary Intervention
Vora AN, Dai D, Gurm H, Amin AP, Messenger JC, Mahmud E, Mauri L, Wang TY, Roe MT, Curtis J, Patel MR, Dauerman HL, Peterson ED, Rao SV. Temporal Trends in the Risk Profile of Patients Undergoing Outpatient Percutaneous Coronary Intervention. Circulation Cardiovascular Interventions 2016, 9: e003070. PMID: 26957417, DOI: 10.1161/circinterventions.115.003070.Peer-Reviewed Original ResearchConceptsRisk profileCathPCI RegistryHospital admissionPatient riskHigh riskCardiology National Cardiovascular Data Registry's CathPCI RegistryNational Cardiovascular Data Registry CathPCI RegistryOutpatient percutaneous coronary interventionPercutaneous coronary intervention (PCI) proceduresProportion of outpatientsProportion of patientsPercutaneous coronary interventionInpatient hospital stayCoronary intervention proceduresPost-PCI complicationsLevel of careOutpatient reimbursementHospital stayCoronary interventionGreater comorbidityOutpatient basisPCI proceduresAmerican CollegeLower riskPatients
2015
National Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010)
Minges KE, Bikdeli B, Wang Y, Kim N, Curtis JP, Desai MM, Krumholz HM. National Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010). The American Journal Of Cardiology 2015, 116: 1436-1442. PMID: 26409636, PMCID: PMC4841688, DOI: 10.1016/j.amjcard.2015.07.068.Peer-Reviewed Original ResearchConceptsHospitalization ratesMortality rateReadmission ratesBlack patientsPrincipal discharge diagnosis codeOlder adultsCause readmission rateHospital mortality rateProportion of patientsRetrospective cohort studyDischarge diagnosis codesSkilled nursing facilitiesNational trendsSignificant racial differencesHigh rateHome health careHospital stayAdults AgedCohort studyMore patientsTherapeutic advancesDiagnosis codesMedicare feeNursing facilitiesSignificant burden
2014
Procedure timing as a predictor of inhospital adverse outcomes from implantable cardioverter-defibrillator implantation: Insights from the National Cardiovascular Data Registry
Hsu JC, Varosy PD, Parzynski CS, Chaudhry SI, Dewland TA, Curtis JP, Marcus GM. Procedure timing as a predictor of inhospital adverse outcomes from implantable cardioverter-defibrillator implantation: Insights from the National Cardiovascular Data Registry. American Heart Journal 2014, 169: 45-52.e3. PMID: 25497247, DOI: 10.1016/j.ahj.2014.10.006.Peer-Reviewed Original ResearchConceptsHospital stayAdverse eventsICD recipientsWeekends/holidaysInhospital deathGreater oddsNational Cardiovascular Data Registry ICD RegistryFirst-time ICD recipientsImplantable cardioverter defibrillator implantationNational Cardiovascular Data RegistryImplantable cardioverter-defibrillator (ICD) proceduresImplantable cardioverter defibrillator recipientsHierarchical multivariable logistic regressionInhospital adverse outcomesCardioverter-defibrillator implantationProlonged hospital stayMultivariable logistic regressionReal-world populationAfternoon/eveningTotal complicationsMultivariable adjustmentAdverse outcomesHospital characteristicsICD implantsData registry
2013
Cardiac Perforation From Implantable Cardioverter-Defibrillator Lead Placement
Hsu JC, Varosy PD, Bao H, Dewland TA, Curtis JP, Marcus GM. Cardiac Perforation From Implantable Cardioverter-Defibrillator Lead Placement. Circulation Cardiovascular Quality And Outcomes 2013, 6: 582-590. PMID: 24002030, DOI: 10.1161/circoutcomes.113.000299.Peer-Reviewed Original ResearchConceptsPredictors of perforationCardiac perforationICD recipientsMajor complicationsGreater oddsImplantable cardioverter defibrillator lead placementHigher left ventricular ejection fractionFirst-time ICD recipientsLeft ventricular ejection fractionHierarchical multivariable logistic regressionHeart failure classICD lead implantationAssociated adverse eventsVentricular ejection fractionMultivariable logistic regressionLength of stayBundle branch blockCardiac bypass surgeryHospital mortalityHospital deathHospital stayBypass surgeryFeared complicationMultivariable adjustmentAdverse events
2012
Low Body Mass Index but Not Obesity Is Associated With In‐Hospital Adverse Events and Mortality Among Implantable Cardioverter‐Defibrillator Recipients: Insights From the National Cardiovascular Data Registry
Hsu JC, Varosy PD, Bao H, Wang Y, Curtis JP, Marcus GM. Low Body Mass Index but Not Obesity Is Associated With In‐Hospital Adverse Events and Mortality Among Implantable Cardioverter‐Defibrillator Recipients: Insights From the National Cardiovascular Data Registry. Journal Of The American Heart Association 2012, 1: e003863. PMID: 23316325, PMCID: PMC3540679, DOI: 10.1161/jaha.112.003863.Peer-Reviewed Original ResearchConceptsBody mass indexNormal weight patientsFirst-time ICD recipientsWeight patientsAdverse eventsICD recipientsHospital deathHospital stayUnderweight patientsICD implantationObese patientsMass indexNational Cardiovascular Data Registry ICD RegistryAssociation of BMINational Cardiovascular Data RegistryLower body mass indexImplantable cardioverter defibrillator recipientsHierarchical multivariable logistic regressionMore periprocedural complicationsHospital adverse eventsMultivariable logistic regressionSudden cardiac deathPatient body habitusReal-world populationHospital complications
2010
Trends in Length of Stay and Short-term Outcomes Among Medicare Patients Hospitalized for Heart Failure, 1993-2006
Bueno H, Ross JS, Wang Y, Chen J, Vidán MT, Normand SL, Curtis JP, Drye EE, Lichtman JH, Keenan PS, Kosiborod M, Krumholz HM. Trends in Length of Stay and Short-term Outcomes Among Medicare Patients Hospitalized for Heart Failure, 1993-2006. JAMA 2010, 303: 2141-2147. PMID: 20516414, PMCID: PMC3020983, DOI: 10.1001/jama.2010.748.Peer-Reviewed Original ResearchConceptsLength of stayShort-term outcomesHeart failureReadmission ratesHospital mortalityDischarge dispositionRisk ratioThirty-day readmission ratesMortality risk ratioSkilled nursing facilitiesHome care servicesHospital stayOlder patientsUnadjusted analysesMedicare patientsObservational studyMedicare feeNursing facilitiesPatientsStayCare servicesMortalityMarked reductionMean lengthOutcomes
2009
Clinical characteristics and in-hospital outcome of patients with end-stage renal disease on dialysis referred for implantable cardioverter-defibrillator implantation
Aggarwal A, Wang Y, Rumsfeld JS, Curtis JP, Heidenreich PA, Registry C. Clinical characteristics and in-hospital outcome of patients with end-stage renal disease on dialysis referred for implantable cardioverter-defibrillator implantation. Heart Rhythm 2009, 6: 1565-1571. PMID: 19879533, DOI: 10.1016/j.hrthm.2009.08.006.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillator implantationESRD patientsCardioverter-defibrillator implantationICD implantationHospital complicationsTotal complicationsHospital stayPrimary preventionEnd-stage renal disease patientsEnd-stage renal diseaseComorbid medical conditionsRenal disease patientsHigh rateERSD patientsHospital mortalityHospital outcomesClinical characteristicsAngiotensin inhibitorsClinical profileICD RegistryMajor complicationsPrimary outcomeRenal diseaseMultivariable analysisDevice implantation