2024
Predicting Major Adverse Events in Patients Undergoing Transcatheter Left Atrial Appendage Occlusion
Faridi K, Ong E, Zimmerman S, Varosy P, Friedman D, Hsu J, Kusumoto F, Mortazavi B, Minges K, Pereira L, Lakkireddy D, Koutras C, Denton B, Mobayed J, Curtis J, Freeman J. Predicting Major Adverse Events in Patients Undergoing Transcatheter Left Atrial Appendage Occlusion. Circulation Arrhythmia And Electrophysiology 2024, 17: e012424. PMID: 38390713, PMCID: PMC11021146, DOI: 10.1161/circep.123.012424.Peer-Reviewed Original ResearchNational Cardiovascular Data RegistryLeft atrial appendage occlusionIn-hospital major adverse eventsMajor adverse eventsBedside risk scoreRisk scoreData RegistryIncreased fall riskAdverse eventsQuality improvement effortsWatchman FLXAppendage occlusionFall riskLeft atrial appendage occlusion procedureRegistry dataImprovement effortsRisk of in-hospital major adverse eventsPredicting major adverse eventsLogistic regressionAdverse event ratesModerate discriminationClinically relevant variablesFemale sexAtrial fibrillation terminationLAAO procedures
2023
Left ventricular lead implantation failure in an unselected nationwide cohort
Friedman D, Qin L, Freeman J, Singh J, Curtis J, Piccini J, Al-Khatib S, Jackson K. Left ventricular lead implantation failure in an unselected nationwide cohort. Heart Rhythm 2023, 20: 1420-1428. PMID: 37406870, DOI: 10.1016/j.hrthm.2023.06.023.Peer-Reviewed Original ResearchImplant failureIndependent predictorsSleep apneaBlack raceFemale sexQRS durationHispanic ethnicityNational Cardiovascular Data Registry ICD RegistryYounger ageLeft bundle branch blockCoronary sinus dissectionPredictors of LVUnselected nationwide cohortVentricular lead implantationCardiac resynchronization therapy (CRT) proceduresObstructive sleep apneaImplant failure rateSignificant independent predictorsBundle branch blockCoronary sinus accessCRT implantationDiaphragmatic stimulationNationwide cohortEjection fractionICD Registry
2022
Sex-based differences in atrial fibrillation ablation adverse events
Mszar R, Friedman D, Ong E, Du C, Wang Y, Zeitler E, Cunningham S, Akar J, Curtis J, Freeman J. Sex-based differences in atrial fibrillation ablation adverse events. Heart 2022, 109: 595-605. PMID: 36104219, DOI: 10.1136/heartjnl-2022-321192.Peer-Reviewed Original ResearchConceptsAcute pulmonary vein isolationAdverse eventsPulmonary vein isolationAtrial fibrillationHigh riskSex-based differencesVein isolationCatheter ablationFemale sexLarge prospective registryHospital adverse eventsMajor adverse eventsObservational cohort studyPhrenic nerve damageAF ablation proceduresQuality of lifeAblation RegistryMore comorbiditiesProspective registryAF ablationCohort studyPericardial effusionNerve damagePatient sexVascular injury
2018
Incidence and Predictors of Perioperative Complications With Transvenous Lead Extractions
Sood N, Martin DT, Lampert R, Curtis JP, Parzynski C, Clancy J. Incidence and Predictors of Perioperative Complications With Transvenous Lead Extractions. Circulation Arrhythmia And Electrophysiology 2018, 11: e004768. PMID: 29453324, DOI: 10.1161/circep.116.004768.Peer-Reviewed Original ResearchConceptsTransvenous lead extractionMajor perioperative complicationsUrgent cardiac surgeryPerioperative complicationsLead extractionCardiac surgeryMajor complicationsClinical statusNational Cardiovascular Data Registry Implantable Cardioverter Defibrillator RegistryImplantable Cardioverter-Defibrillator RegistryRecent single-center studiesMultivariable logistic regression analysisHigh-voltage leadsReal-world incidenceSingle-center studyImplantable cardioverter-defibrillator leadsPatient's clinical statusHigh-volume centersRisk of complicationsLogistic regression analysisCardiovascular implantable electronic devicesCardioverter-defibrillator leadsReal-world outcomesImplantable electronic devicesFemale sex
2016
Long-Term Risk for Device-Related Complications and Reoperations After Implantable Cardioverter-Defibrillator Implantation: An Observational Cohort Study.
Ranasinghe I, Parzynski CS, Freeman JV, Dreyer RP, Ross JS, Akar JG, Krumholz HM, Curtis JP. Long-Term Risk for Device-Related Complications and Reoperations After Implantable Cardioverter-Defibrillator Implantation: An Observational Cohort Study. Annals Of Internal Medicine 2016, 165: 20-29. PMID: 27135392, DOI: 10.7326/m15-2732.Peer-Reviewed Original ResearchICD-related complicationsNational Cardiovascular Data RegistryObservational cohort studyDevice-related complicationsICD implantationLong-term riskCohort studyMedicare feeNational Cardiovascular Data Registry ICD RegistryImplantable cardioverter defibrillator implantationImplantable cardioverter-defibrillator placementCardioverter-defibrillator implantationService claims dataCRT-D devicesSingle-chamber devicesCumulative incidenceNonfatal outcomesICD RegistryService patientsBlack raceFemale sexReoperationAmerican CollegeClaims dataComplications