2020
Survival Following Implantable Cardioverter‐Defibrillator Implantation in Patients With Amyloid Cardiomyopathy
Higgins AY, Annapureddy AR, Wang Y, Minges KE, Lampert R, Rosenfeld LE, Jacoby DL, Curtis JP, Miller EJ, Freeman JV. Survival Following Implantable Cardioverter‐Defibrillator Implantation in Patients With Amyloid Cardiomyopathy. Journal Of The American Heart Association 2020, 9: e016038. PMID: 32867553, PMCID: PMC7726970, DOI: 10.1161/jaha.120.016038.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillator implantationCardioverter-defibrillator implantationNonischemic cardiomyopathyCardiac amyloidosisDiabetes mellitusCerebrovascular diseaseVentricular tachycardiaMultivariable Cox proportional hazards regression modelsCox proportional hazards regression modelProportional hazards regression modelsKaplan-Meier survival curvesCox proportional hazards modelPropensity-matched cohortOutcomes of patientsHazards regression modelsProportional hazards modelCause mortalityICD implantationRenal functionMultivariable analysisConclusions MortalityRisk factorsRegistry dataAmyloid cardiomyopathyHigh riskSex Differences in 1‐Year Health Status Following Percutaneous Coronary Intervention in Patients Without Acute Myocardial Infarction: Results From the China PEACE Prospective Study
Zheng X, Dreyer RP, Curtis JP, Liu S, Xu X, Bai X, Li X, Zhang H, Wang S, Masoudi FA, Spertus JA, Li J, Krumholz HM, Group F. Sex Differences in 1‐Year Health Status Following Percutaneous Coronary Intervention in Patients Without Acute Myocardial Infarction: Results From the China PEACE Prospective Study. Journal Of The American Heart Association 2020, 9: e014421. PMID: 32131687, PMCID: PMC7335522, DOI: 10.1161/jaha.119.014421.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionAcute myocardial infarctionSAQ Summary ScoreCoronary interventionHealth status outcomesMyocardial infarctionHealth statusSummary scoresSAQ qualityAngina frequencyStatus outcomesPercutaneous coronary intervention studiesSAQ angina frequency scoreAngina frequency scoreCoronary Intervention StudyMarginal clinical significanceSAQ angina frequencyCardiac risk factorsChinese tertiary hospitalBackground Sex differencesSex differencesMultivariable adjustmentDiabetes mellitusTertiary hospitalLife scores
2018
Clinical Model to Predict 90-Day Risk of Readmission After Acute Myocardial Infarction
Kini V, Peterson PN, Spertus JA, Kennedy KF, Arnold SV, Wasfy JH, Curtis JP, Bradley SM, Amin AP, Ho PM, Masoudi FA. Clinical Model to Predict 90-Day Risk of Readmission After Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2018, 11: e004788. PMID: 30354578, PMCID: PMC6214661, DOI: 10.1161/circoutcomes.118.004788.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionPredictors of readmissionSimple risk scoreDays of hospitalizationGroup of patientsProportional hazards regressionCause readmissionCoronary revascularizationClinical characteristicsCohort studyHospital dischargeDiabetes mellitusHeart failureHazards regressionReadmission riskUnique patientsTransitional careACTION RegistryPrimary diagnosisValue-based reimbursementIndividual patientsReadmissionRisk scoreLower riskHeart Failure After Ischemic Stroke or Transient Ischemic Attack in Insulin-Resistant Patients Without Diabetes Mellitus Treated With Pioglitazone
Young LH, Viscoli CM, Schwartz GG, Inzucchi SE, Curtis JP, Gorman MJ, Furie KL, Conwit R, Spatz E, Lovejoy A, Abbott JD, Jacoby DL, Kolansky DM, Ling FS, Pfau SE, Kernan WN. Heart Failure After Ischemic Stroke or Transient Ischemic Attack in Insulin-Resistant Patients Without Diabetes Mellitus Treated With Pioglitazone. Circulation 2018, 138: 1210-1220. PMID: 29934374, PMCID: PMC6202153, DOI: 10.1161/circulationaha.118.034763.Peer-Reviewed Original ResearchConceptsRisk of HFTransient ischemic attackEffect of pioglitazoneHF riskHeart failureInsulin-resistant patientsMyocardial infarctionIschemic attackCardiovascular benefitsIschemic strokeDiabetes mellitusInsulin resistanceHigher C-reactive proteinComposite of strokeHF risk scoreHigher HF riskDrug dose reductionHospitalized heart failureIncident myocardial infarctionLower mean doseC-reactive proteinBaseline patient featuresHF hospitalizationCardiovascular eventsPlacebo group
2017
Cardiac Outcomes After Ischemic Stroke or Transient Ischemic Attack
Young LH, Viscoli CM, Curtis JP, Inzucchi SE, Schwartz GG, Lovejoy AM, Furie KL, Gorman MJ, Conwit R, Abbott JD, Jacoby DL, Kolansky DM, Pfau SE, Ling FS, Kernan WN. Cardiac Outcomes After Ischemic Stroke or Transient Ischemic Attack. Circulation 2017, 135: 1882-1893. PMID: 28246237, PMCID: PMC5511545, DOI: 10.1161/circulationaha.116.024863.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeType 1 myocardial infarctionTransient ischemic attackMyocardial infarctionCoronary syndromeInsulin resistanceIschemic attackIschemic strokeDiabetes mellitusSerum troponinAcute coronary syndrome episodeMean age 63 yearsAcute coronary syndrome eventIndependent clinical events committeeType 2 myocardial infarctionIRIS participantsImpact of pioglitazoneRecent cerebrovascular eventsRecent ischemic strokeClinical events committeeAge 63 yearsEffect of pioglitazoneSmall myocardial infarctionCoronary artery diseaseST-segment elevation
2016
Association Between a Prolonged PR Interval and Outcomes of Cardiac Resynchronization Therapy
Friedman DJ, Bao H, Spatz ES, Curtis JP, Daubert JP, Al-Khatib SM. Association Between a Prolonged PR Interval and Outcomes of Cardiac Resynchronization Therapy. Circulation 2016, 134: 1617-1628. PMID: 27760795, PMCID: PMC5418126, DOI: 10.1161/circulationaha.116.022913.Peer-Reviewed Original ResearchConceptsHeart failure hospitalizationFailure hospitalizationPR intervalImplantable cardioverter defibrillatorNational Cardiovascular Data Registry ICD RegistryCardiac resynchronization therapy candidatesIncident heart failure hospitalizationReal-world comparative effectivenessCRT-eligible patientsReceipt of CRTChronic kidney diseaseCardiac resynchronization therapyCRT-D patientsCoronary artery diseaseProlonged PR intervalComparative effectiveness analysisMore comorbiditiesArtery diseaseDiabetes mellitusICD recipientsICD RegistryResynchronization therapyAtrial arrhythmiasKidney diseaseCardioverter defibrillator
2014
Survival After Primary Prevention Implantable Cardioverter-Defibrillator Placement Among Patients With Chronic Kidney Disease
Hess PL, Hellkamp AS, Peterson ED, Sanders GD, Al-Khalidi HR, Curtis LH, Hammill BG, Pun PH, Curtis JP, Anstrom KJ, Hammill SC, Al-Khatib SM. Survival After Primary Prevention Implantable Cardioverter-Defibrillator Placement Among Patients With Chronic Kidney Disease. Circulation Arrhythmia And Electrophysiology 2014, 7: 793-799. PMID: 25038119, PMCID: PMC4206571, DOI: 10.1161/circep.114.001455.Peer-Reviewed Original ResearchMeSH KeywordsAgedCause of DeathChi-Square DistributionComorbidityDeath, Sudden, CardiacDefibrillators, ImplantableElectric CountershockFemaleGlomerular Filtration RateHeart FailureHumansKaplan-Meier EstimateKidneyLinear ModelsMaleMiddle AgedMultivariate AnalysisPatient SelectionPrimary PreventionProportional Hazards ModelsProsthesis DesignRegistriesRenal Insufficiency, ChronicRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeUnited StatesConceptsChronic kidney diseasePrimary prevention ICD placementRisk of deathICD placementCKD severityKidney diseaseNational Cardiovascular Data Registry ICD RegistryPrimary prevention implantable cardioverter-defibrillator placementGlomerular filtration rate 30Implantable cardioverter-defibrillator candidatesEnd-stage renal diseaseImplantable cardioverter-defibrillator placementSocial Security Death Master FileHeart failure symptomsLow ejection fractionGlomerular filtration rateRate of deathDeath Master FileICD candidacyCKD stageDiabetes mellitusEjection fractionICD RegistryRenal diseaseSerum sodiumClinical Prediction Model Suitable for Assessing Hospital Quality for Patients Undergoing Carotid Endarterectomy
Wimmer NJ, Spertus JA, Kennedy KF, Anderson HV, Curtis JP, Weintraub WS, Singh M, Rumsfeld JS, Masoudi FA, Yeh RW. Clinical Prediction Model Suitable for Assessing Hospital Quality for Patients Undergoing Carotid Endarterectomy. Journal Of The American Heart Association 2014, 3: e000728. PMID: 24938712, PMCID: PMC4309056, DOI: 10.1161/jaha.113.000728.Peer-Reviewed Original ResearchConceptsCarotid artery revascularizationCarotid endarterectomyHospital strokeHospital qualityArtery diseaseCEA scoreNew York Heart Association class IIIHospital risk-adjusted outcomesPrimary end-point eventPrior peripheral artery diseaseContralateral carotid occlusionHospital-level clusteringSymptomatic carotid lesionsPeripheral artery diseaseEnd-point eventsCoronary artery diseaseModerate discriminative abilityRisk-adjusted outcomesClinical prediction modelHierarchical logistic regressionArtery revascularizationEndarterectomy (CARE) RegistryAppropriate risk adjustmentCarotid occlusionDiabetes mellitus
2010
Prevalence and Predictors of Off-Label Use of Cardiac Resynchronization Therapy in Patients Enrolled in the National Cardiovascular Data Registry Implantable Cardiac-Defibrillator Registry
Fein AS, Wang Y, Curtis JP, Masoudi FA, Varosy PD, Reynolds MR, Registry C. Prevalence and Predictors of Off-Label Use of Cardiac Resynchronization Therapy in Patients Enrolled in the National Cardiovascular Data Registry Implantable Cardiac-Defibrillator Registry. Journal Of The American College Of Cardiology 2010, 56: 766-773. PMID: 20797489, PMCID: PMC2958057, DOI: 10.1016/j.jacc.2010.05.025.Peer-Reviewed Original ResearchConceptsNew York Heart Association functional classYork Heart Association functional classQRS interval durationLabel useConsensus guidelinesMultivariable hierarchical logistic regression modelsPrevious percutaneous coronary interventionAtrial fibrillation/flutterEvidence-based consensus guidelinesFunctional classGuideline-based indicationsPrimary prevention indicationCardiac resynchronization therapyPercutaneous coronary interventionOff-label useHierarchical logistic regression modelsInterval durationLogistic regression modelsStudy time frameApplication of CRTCoronary interventionPrevention indicationDiabetes mellitusEjection fractionResynchronization therapy