2022
Cardiovascular and Limb Events Following Endovascular Revascularization Among Patients ≥65 Years Old: An American College of Cardiology PVI Registry Analysis
Weissler EH, Wang Y, Gales JM, Feldman DN, Arya S, Secemsky EA, Aronow HD, Hawkins BM, Gutierrez JA, Patel MR, Curtis JP, Jones WS, Swaminathan RV. Cardiovascular and Limb Events Following Endovascular Revascularization Among Patients ≥65 Years Old: An American College of Cardiology PVI Registry Analysis. Journal Of The American Heart Association 2022, 11: e024279. PMID: 35723018, PMCID: PMC9238644, DOI: 10.1161/jaha.121.024279.Peer-Reviewed Original ResearchChronic limb threatening ischemiaPeripheral vascular interventionsEnd-stage renal diseasePeripheral artery diseasePrimary outcomeRenal diseaseAmerican CollegeLimb eventsNon-modifiable patient factorsOccurrence of MACEPredictors of MACELimb threatening ischemiaCongestive heart failureProportional hazards regressionSevere lung diseaseMedicaid Services dataExperience higher ratesEndovascular revascularizationPrior CABGConclusions PatientsArtery diseaseHeart failurePatient factorsBypass graftResults Patients
2021
Sex Differences in Procedural Outcomes Among Patients Undergoing Left Atrial Appendage Occlusion
Darden D, Duong T, Du C, Munir MB, Han FT, Reeves R, Saw J, Zeitler EP, Al-Khatib SM, Russo AM, Minges KE, Curtis JP, Freeman JV, Hsu JC. Sex Differences in Procedural Outcomes Among Patients Undergoing Left Atrial Appendage Occlusion. JAMA Cardiology 2021, 6: 1275-1284. PMID: 34379072, PMCID: PMC8358791, DOI: 10.1001/jamacardio.2021.3021.Peer-Reviewed Original ResearchConceptsHospital adverse eventsMajor adverse eventsAdverse eventsAtrial appendage occlusionMajor bleedingPericardial effusionAppendage occlusionAtrial fibrillationSex differencesCongestive heart failureCoronary artery diseaseAdjusted logistic regression analysisParoxysmal atrial fibrillationLogistic regression analysisMultivariable adjusted logistic regression analysesPrior strokeUncontrolled hypertensionHospital outcomesHospital stayMultivariable adjustmentProlonged hospitalBaseline characteristicsCohort studySelect patientsArtery diseaseComparative Outcomes of Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction Among Medicare Beneficiaries With Multivessel Coronary Artery Disease
Secemsky EA, Butala N, Raja A, Khera R, Wang Y, Curtis JP, Maddox TM, Virani SS, Armstrong EJ, Shunk KA, Brindis RG, Bhatt D, Yeh RW. Comparative Outcomes of Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction Among Medicare Beneficiaries With Multivessel Coronary Artery Disease. Circulation Cardiovascular Interventions 2021, 14: e010323. PMID: 34372676, PMCID: PMC8485756, DOI: 10.1161/circinterventions.120.010323.Peer-Reviewed Original Research
2020
Revascularization Practices and Outcomes in Patients With Multivessel Coronary Artery Disease Who Presented With Acute Myocardial Infarction and Cardiogenic Shock in the US, 2009-2018
Khera R, Secemsky EA, Wang Y, Desai NR, Krumholz HM, Maddox TM, Shunk KA, Virani SS, Bhatt DL, Curtis J, Yeh RW. Revascularization Practices and Outcomes in Patients With Multivessel Coronary Artery Disease Who Presented With Acute Myocardial Infarction and Cardiogenic Shock in the US, 2009-2018. JAMA Internal Medicine 2020, 180: 1317-1327. PMID: 32833024, PMCID: PMC9377424, DOI: 10.1001/jamainternmed.2020.3276.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCohort StudiesCoronary VesselsFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedMyocardial InfarctionPatient DischargePercutaneous Coronary InterventionRisk AssessmentRisk FactorsShock, CardiogenicST Elevation Myocardial InfarctionTime FactorsTreatment OutcomeUnited StatesConceptsST-segment elevation myocardial infarctionMultivessel percutaneous coronary interventionMultivessel coronary artery diseasePercutaneous coronary interventionAcute myocardial infarctionCoronary artery diseaseCulprit vessel percutaneous coronary interventionCardiogenic shockHospital mortalityArtery diseaseMyocardial infarctionCohort studyPrimary outcomeHospital variationPCI strategyMedicare beneficiariesUnderwent multivessel PCISignificant hospital variationElevation myocardial infarctionSubset of patientsHigh-risk populationRecent evidenceHospital complicationsPCI useRevascularization practiceCOVID-19 infections and outcomes in a live registry of heart failure patients across an integrated health care system
Caraballo C, McCullough M, Fuery MA, Chouairi F, Keating C, Ravindra NG, Miller PE, Malinis M, Kashyap N, Hsiao A, Wilson FP, Curtis JP, Grant M, Velazquez EJ, Desai NR, Ahmad T. COVID-19 infections and outcomes in a live registry of heart failure patients across an integrated health care system. PLOS ONE 2020, 15: e0238829. PMID: 32997657, PMCID: PMC7526909, DOI: 10.1371/journal.pone.0238829.Peer-Reviewed Original ResearchConceptsHeart failure patientsIntegrated health care systemHeart Failure RegistryHealth care systemFailure patientsCOVID-19 infectionCare systemCOVID-19SARS-CoV-2 infectionReal-time registryRenin-angiotensin blockersRetrospective chart reviewCoronary artery diseaseRisk of deathCOVID-19 testingAngiotensin blockersMultiple comorbiditiesRespiratory failureChart reviewSymptomatic patientsArtery diseaseHeart failureComorbid conditionsPatient mortalityClinical management
2016
Association Between a Prolonged PR Interval and Outcomes of Cardiac Resynchronization Therapy
Friedman DJ, Bao H, Spatz ES, Curtis JP, Daubert JP, Al-Khatib SM. Association Between a Prolonged PR Interval and Outcomes of Cardiac Resynchronization Therapy. Circulation 2016, 134: 1617-1628. PMID: 27760795, PMCID: PMC5418126, DOI: 10.1161/circulationaha.116.022913.Peer-Reviewed Original ResearchConceptsHeart failure hospitalizationFailure hospitalizationPR intervalImplantable cardioverter defibrillatorNational Cardiovascular Data Registry ICD RegistryCardiac resynchronization therapy candidatesIncident heart failure hospitalizationReal-world comparative effectivenessCRT-eligible patientsReceipt of CRTChronic kidney diseaseCardiac resynchronization therapyCRT-D patientsCoronary artery diseaseProlonged PR intervalComparative effectiveness analysisMore comorbiditiesArtery diseaseDiabetes mellitusICD recipientsICD RegistryResynchronization therapyAtrial arrhythmiasKidney diseaseCardioverter defibrillatorCoronary Catheterization and Percutaneous Coronary Intervention in China: 10-Year Results From the China PEACE-Retrospective CathPCI Study
Zheng X, Curtis JP, Hu S, Wang Y, Yang Y, Masoudi FA, Spertus JA, Li X, Li J, Dharmarajan K, Downing NS, Krumholz HM, Jiang L. Coronary Catheterization and Percutaneous Coronary Intervention in China: 10-Year Results From the China PEACE-Retrospective CathPCI Study. JAMA Internal Medicine 2016, 176: 512. PMID: 26974883, PMCID: PMC5459379, DOI: 10.1001/jamainternmed.2016.0166.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngina, UnstableCardiac CatheterizationChinaCoronary Artery DiseaseDrug-Eluting StentsFemaleHospital MortalityHospitals, UrbanHumansLength of StayMaleMedical RecordsMiddle AgedMyocardial InfarctionOdds RatioOutcome Assessment, Health CarePercutaneous Coronary InterventionPostoperative ComplicationsPostoperative HemorrhageQuality of Health CareRetrospective StudiesStentsTime-to-TreatmentConceptsPercutaneous coronary interventionDrug-eluting stentsQuality of careCoronary catheterizationCoronary interventionNonobstructive coronary artery diseasePrimary percutaneous coronary interventionFuture quality improvement initiativesEvidence-based medicationsOutcomes of patientsCoronary artery diseaseClinical observational studyUse of catheterizationQuality improvement initiativesCalendar year 2001Hospital mortalityArtery diseasePatient characteristicsStable patientsTreatment patternsMedian lengthMean agePCI proceduresMedical recordsObservational study
2015
Appropriate Use Criteria for Coronary Revascularization and Trends in Utilization, Patient Selection, and Appropriateness of Percutaneous Coronary Intervention
Desai NR, Bradley SM, Parzynski CS, Nallamothu BK, Chan PS, Spertus JA, Patel MR, Ader J, Soufer A, Krumholz HM, Curtis JP. Appropriate Use Criteria for Coronary Revascularization and Trends in Utilization, Patient Selection, and Appropriateness of Percutaneous Coronary Intervention. JAMA 2015, 314: 2045-2053. PMID: 26551163, PMCID: PMC5459470, DOI: 10.1001/jama.2015.13764.Peer-Reviewed Original ResearchConceptsNonacute percutaneous coronary interventionPercutaneous coronary interventionAppropriate use criteriaInappropriate percutaneous coronary interventionHospital-level variationCoronary revascularizationPatient selectionUse criteriaCoronary interventionStudy periodAppropriateness of PCINational Cardiovascular Data Registry CathPCI RegistryProportion of PCIsMultivessel coronary artery diseaseHigh-risk findingsCoronary artery diseaseAnnual PCI volumesCross-sectional analysisAngina severityAntianginal medicationsAcute indicationsCathPCI RegistryArtery diseasePCI volumePCI proceduresThe Variation in Recovery
Spatz ES, Curry LA, Masoudi FA, Zhou S, Strait KM, Gross CP, Curtis JP, Lansky AJ, Soares Barreto-Filho JA, Lampropulos JF, Bueno H, Chaudhry SI, D'Onofrio G, Safdar B, Dreyer RP, Murugiah K, Spertus JA, Krumholz HM. The Variation in Recovery. Circulation 2015, 132: 1710-1718. PMID: 26350057, PMCID: PMC4858327, DOI: 10.1161/circulationaha.115.016502.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge of OnsetAlgorithmsAortic DissectionClassificationCoronary DiseaseDiagnostic Techniques, CardiovascularFemaleHumansMaleMedical RecordsMiddle AgedMyocardial InfarctionMyocardiumOxygen ConsumptionPhenotypePlaque, AtheroscleroticProspective StudiesReproducibility of ResultsRisk FactorsSex FactorsTreatment OutcomeYoung AdultConceptsAcute myocardial infarctionCoronary artery diseaseArtery diseaseClinical phenotypeNonobstructive coronary artery diseaseYoung AMI Patients (VIRGO) studyObstructive coronary artery diseaseYoung womenType 2 acute myocardial infarctionBiological disease mechanismsSubset of patientsThird universal definitionUnique clinical phenotypeCulprit lesionClinical characteristicsMyocardial infarctionTherapeutic efficacyUniversal definitionStudy participantsPatientsSupply-demand mismatchYoung adultsDisease mechanismsPatient studiesCurrent classification schemesAntithrombotic Therapy and Outcomes After ICD Implantation in Patients With Atrial Fibrillation and Coronary Artery Disease: An Analysis From the National Cardiovascular Data Registry (NCDR)®
Ghanbari H, Nallamothu BK, Wang Y, Curtis JP. Antithrombotic Therapy and Outcomes After ICD Implantation in Patients With Atrial Fibrillation and Coronary Artery Disease: An Analysis From the National Cardiovascular Data Registry (NCDR)®. Journal Of The American Heart Association 2015, 4: e001331. PMID: 25637345, PMCID: PMC4345865, DOI: 10.1161/jaha.114.001331.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrial FibrillationCoronary Artery DiseaseDefibrillators, ImplantableDrug Therapy, CombinationFemaleFibrinolytic AgentsHemorrhageHumansIncidenceMaleMedicareMiddle AgedPatient DischargePlatelet Aggregation InhibitorsRegistriesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesWarfarinConceptsImplantable cardioverter defibrillator implantationCardioverter-defibrillator implantationCoronary artery diseaseMajor adverse cardiovascular eventsNational Cardiovascular Data RegistryAdverse cardiovascular eventsDevice-related complicationsAntithrombotic agentsDefibrillator implantationArtery diseaseAtrial fibrillationAntithrombotic therapyBleeding riskCardiovascular eventsThromboembolic eventsNational Cardiovascular Data Registry Implantable Cardioverter Defibrillator RegistryImplantable Cardioverter-Defibrillator RegistryHigh bleeding riskCombination of DAHospital dischargeICD implantationPrimary outcomeData registryPatientsFibrillation
2014
Coronary Artery Bypass Graft Surgery Versus Drug-Eluting Stents for Patients With Isolated Proximal Left Anterior Descending Disease
Hannan EL, Zhong Y, Walford G, Holmes DR, Venditti FJ, Berger PB, Jacobs AK, Stamato NJ, Curtis JP, Sharma S, King SB. Coronary Artery Bypass Graft Surgery Versus Drug-Eluting Stents for Patients With Isolated Proximal Left Anterior Descending Disease. Journal Of The American College Of Cardiology 2014, 64: 2717-2726. PMID: 25541122, DOI: 10.1016/j.jacc.2014.09.074.Peer-Reviewed Original ResearchConceptsDrug-eluting stentsPercutaneous coronary interventionRepeat revascularization rateMyocardial infarctionRevascularization ratesCABG patientsAnterior descending (LAD) coronary artery diseaseCoronary artery bypass graft surgeryLower repeat revascularization ratesArtery bypass graft surgeryCox proportional hazards modelBypass graft surgeryCoronary artery diseaseKaplan-Meier estimatesProportional hazards modelAdministrative dataIsolated ProximalCABG surgeryGraft surgeryCoronary interventionArtery diseaseVital statistics dataCurrent guidelinesCABGOutcome measuresClinical Prediction Model Suitable for Assessing Hospital Quality for Patients Undergoing Carotid Endarterectomy
Wimmer NJ, Spertus JA, Kennedy KF, Anderson HV, Curtis JP, Weintraub WS, Singh M, Rumsfeld JS, Masoudi FA, Yeh RW. Clinical Prediction Model Suitable for Assessing Hospital Quality for Patients Undergoing Carotid Endarterectomy. Journal Of The American Heart Association 2014, 3: e000728. PMID: 24938712, PMCID: PMC4309056, DOI: 10.1161/jaha.113.000728.Peer-Reviewed Original ResearchConceptsCarotid artery revascularizationCarotid endarterectomyHospital strokeHospital qualityArtery diseaseCEA scoreNew York Heart Association class IIIHospital risk-adjusted outcomesPrimary end-point eventPrior peripheral artery diseaseContralateral carotid occlusionHospital-level clusteringSymptomatic carotid lesionsPeripheral artery diseaseEnd-point eventsCoronary artery diseaseModerate discriminative abilityRisk-adjusted outcomesClinical prediction modelHierarchical logistic regressionArtery revascularizationEndarterectomy (CARE) RegistryAppropriate risk adjustmentCarotid occlusionDiabetes mellitus
2011
Influence of Age on Perioperative Complications Among Patients Undergoing Implantable Cardioverter-Defibrillators for Primary Prevention in the United States
Tsai V, Goldstein MK, Hsia HH, Wang Y, Curtis J, Heidenreich PA. Influence of Age on Perioperative Complications Among Patients Undergoing Implantable Cardioverter-Defibrillators for Primary Prevention in the United States. Circulation Cardiovascular Quality And Outcomes 2011, 4: 549-556. PMID: 21878667, DOI: 10.1161/circoutcomes.110.959205.Peer-Reviewed Original ResearchConceptsAdverse eventsICD RegistryPrimary prevention ICD recipientsEnd pointImplantable cardioverter defibrillator recipientsPatients 85 yearsPrimary prevention patientsMinor adverse eventsPrimary end pointSecondary end pointsMajor adverse eventsCongestive heart failureCoronary artery diseaseLength of stayInfluence of ageHospital mortalityICD trialsPerioperative complicationsPeriprocedural complicationsArtery diseaseHeart failureICD recipientsRenal diseaseIncreased oddsAtrial fibrillation
2009
Impact of Baseline Renal Function on Outcomes of Renal Artery Stenting in Hypertensive Patients
Singer GM, Remetz MS, Curtis JP, Setaro JF. Impact of Baseline Renal Function on Outcomes of Renal Artery Stenting in Hypertensive Patients. Journal Of Clinical Hypertension 2009, 11: 615-620. PMID: 19878369, PMCID: PMC8673102, DOI: 10.1111/j.1751-7176.2009.00167.x.Peer-Reviewed Original ResearchConceptsRenal artery stentingSystolic blood pressureBlood pressureRenal functionArtery stentingObstructive renal artery diseaseResistant hypertension patientsBaseline renal functionImpaired renal functionGlomerular filtration rateRenal artery diseaseHypertensive patientsRenal dysfunctionArtery diseaseConsecutive patientsHypertension patientsRenal arteryFiltration ratePatientsEGFRGreat benefitMonthsStentingHgArtery