2024
Healthy immigrant community study protocol: A randomized controlled trial of a social network intervention for cardiovascular risk reduction among Hispanic and Somali adults
Wieland M, Molina L, Goodson M, Capetillo G, Osman A, Ahmed Y, Elmi H, Nur O, Iteghete S, Torres-Herbeck G, Dirie H, Clark M, Lohr A, Smith K, Zeratsky K, Rieck T, Herrin J, Valente T, Sia I. Healthy immigrant community study protocol: A randomized controlled trial of a social network intervention for cardiovascular risk reduction among Hispanic and Somali adults. Contemporary Clinical Trials 2024, 138: 107465. PMID: 38309526, PMCID: PMC10923143, DOI: 10.1016/j.cct.2024.107465.Peer-Reviewed Original ResearchConceptsLife's Simple 7Social network interventionsHealth promotionCardiovascular risk factorsCardiovascular risk reductionAmerican Heart Association's Life's Simple 7Health promotion interventionsPhysical activity levelsNetwork interventionsStepped wedge cluster randomized designReducing cardiovascular risk factorsCluster randomized trialStepped wedge cluster randomized trialNegative health behaviorsCluster randomized designRisk factorsHealthy weight lossRisk reductionRandomized controlled trialsImmigrant populationPromotion interventionsSomali adultsHealth behaviorsSomali immigrant communityWaist circumference
2022
Perioperative magnetic resonance imaging in breast cancer care: Distinct adoption trajectories among physician patient-sharing networks
Xu X, Soulos PR, Herrin J, Wang SY, Pollack CE, Killelea BK, Forman HP, Gross CP. Perioperative magnetic resonance imaging in breast cancer care: Distinct adoption trajectories among physician patient-sharing networks. PLOS ONE 2022, 17: e0265188. PMID: 35290417, PMCID: PMC8923453, DOI: 10.1371/journal.pone.0265188.Peer-Reviewed Original ResearchConceptsPhysician patient-sharing networksPerioperative magnetic resonance imagingClinical risk factorsMagnetic resonance imagingPatient clinical risk factorsPatient-sharing networksBreast cancer careRisk-adjusted ratesMastectomy usePhysician networksCancer careRisk factorsEnd Results-Medicare databaseCharacteristics of patientsProportion of patientsBreast cancer surgeryComposition of patientsMRI adoptionDistinct trajectoriesMore patientsCancer surgeryClinical outcomesCancer specialistsMRI usePatients
2020
Illuminating Hospital Disparities in Readmissions for Patients with Social Risk Factors: Comparing Hospital Performance Using Two Different Approaches
Herrin J, Peltz A, Zhou S, Du C, Barbo A, Charania S, Schwartz M, Lin Z, Bernheim S. Illuminating Hospital Disparities in Readmissions for Patients with Social Risk Factors: Comparing Hospital Performance Using Two Different Approaches. Health Services Research 2020, 55: 93-94. PMCID: PMC7440563, DOI: 10.1111/1475-6773.13462.Peer-Reviewed Original ResearchSocial risk factorsAbsolute risk differenceDual eligibility statusHospital disparitiesRisk factorsDual eligibilityMedicare patientsReadmission ratesOdds ratioRisk differenceSocioeconomic disparitiesMedicare FFS patientsRetrospective cohort studyClinical risk factorsCommon clinical conditionHospitalized Medicare patientsSES indexStandard Analytic FilesVeterans Affairs hospitalEligibility statusMedicare Part AHospital outcomesCohort studyFFS patientsHospital readmission
2019
Abandonment trajectories of conventionally fractionated adjuvant radiotherapy in breast cancer care.
Xu X, Soulos P, Herrin J, Wang S, Pollack C, Evans S, Gross C, Yu J. Abandonment trajectories of conventionally fractionated adjuvant radiotherapy in breast cancer care. Journal Of Clinical Oncology 2019, 37: 531-531. DOI: 10.1200/jco.2019.37.15_suppl.531.Peer-Reviewed Original ResearchPhysician peer groupsBreast cancer careAdjuvant radiotherapyCancer careHigher useNational Medicare claimsPatient risk factorsDistinct trajectoriesYears of ageLow useDifferent baseline levelsRisk-adjusted ratesPatient cohortRisk factorsBreast cancerCost implicationsMedicare claimsBaseline levelsRadiotherapyMedicare perspectiveCFRTCurve analysisPhysiciansPatientsLatent growth curve analysisDo pregnant women living in higher well-being populations in the USA experience lower risk of preterm delivery? A cross-sectional study
Riley C, Roy B, Herrin J, Spatz E, Silvestri MT, Arora A, Kell KP, Rula EY, Krumholz HM. Do pregnant women living in higher well-being populations in the USA experience lower risk of preterm delivery? A cross-sectional study. BMJ Open 2019, 9: e024143. PMID: 31048427, PMCID: PMC6501974, DOI: 10.1136/bmjopen-2018-024143.Peer-Reviewed Original ResearchConceptsPreterm birthCross-sectional studyIndividual risk factorsPreterm deliveryRisk factorsPregnant womenLower riskMaternal risk factorsPrimary outcome measurePrimary independent variableGestational ageMaternal riskOutcome measuresUS birthsHealth StatisticsBirth dataBeing IndexWomenBirthGallup-Sharecare WellLower ratesQuintileRiskDeliveryPopulationEducation level and outcomes after acute myocardial infarction in China
Huo X, Khera R, Zhang L, Herrin J, Bai X, Wang Q, Lu Y, Nasir K, Hu S, Li J, Li X, Zheng X, Masoudi FA, Spertus JA, Krumholz HM, Jiang L. Education level and outcomes after acute myocardial infarction in China. Heart 2019, 105: 946. PMID: 30661037, PMCID: PMC6582708, DOI: 10.1136/heartjnl-2018-313752.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsLow educational attainmentAcute myocardial infarction (AMI) outcomesAdverse cardiovascular eventsFuture healthcare interventionsMyocardial infarction outcomesCardiovascular risk factorsRisk-adjusted analysisAcute myocardial infarctionMedian participant ageCardiovascular eventsCause mortalityAdverse eventsConsecutive patientsAMI outcomesChina PatientUnadjusted analysesMyocardial infarctionRisk factorsChinese cohortHigh riskEducational attainmentEducational attainment groupsHealthcare interventionsPatients
2018
Recurrent hospitalizations for severe hypoglycemia and hyperglycemia among U.S. adults with diabetes
McCoy RG, Herrin J, Lipska KJ, Shah ND. Recurrent hospitalizations for severe hypoglycemia and hyperglycemia among U.S. adults with diabetes. Journal Of Diabetes And Its Complications 2018, 32: 693-701. PMID: 29751961, PMCID: PMC6015781, DOI: 10.1016/j.jdiacomp.2018.04.007.Peer-Reviewed Original ResearchConceptsRecurrent hyperglycemiaRecurrent hypoglycemiaNew glucose-lowering medicationsPost-discharge managementGlucose-lowering medicationsHigh-risk patientsOptumLabs Data WarehouseHypoglycemia hospitalizationIndex dischargeOlder patientsRisk patientsUnrelated causesSevere hypoglycemiaRecurrent hospitalizationsNational cohortEarly recognitionPrincipal diagnosisRisk factorsRetrospective analysisHyperglycemiaHypoglycemiaPatientsReadmissionU.S. adultsHospitalization
2017
Predictors of Return Visits Among Insured Emergency Department Mental Health and Substance Abuse Patients, 2005-2013
Lee S, Herrin J, Bobo WV, Johnson R, Sangaralingham LR, Campbell RL. Predictors of Return Visits Among Insured Emergency Department Mental Health and Substance Abuse Patients, 2005-2013. Western Journal Of Emergency Medicine 2017, 18: 884-893. PMID: 28874941, PMCID: PMC5576625, DOI: 10.5811/westjem.2017.6.33850.Peer-Reviewed Original ResearchConceptsED visitsReturn visitsInpatient admissionsOptum Labs Data WarehouseMental healthChronic medical comorbiditiesContinuous insurance enrollmentFirst ED visitIndex ED visitRetrospective cohort studyAdministrative claims dataMedicare Advantage enrolleesPrior EDMedical comorbiditiesCohort studyAcute carePrimary diagnosisStudy inclusionRisk factorsInpatient utilizationClaims dataIncreased ageSubstance abusePatientsStudy periodHospital Readmissions among Commercially Insured and Medicare Advantage Beneficiaries with Diabetes and the Impact of Severe Hypoglycemic and Hyperglycemic Events
McCoy RG, Lipska KJ, Herrin J, Jeffery MM, Krumholz HM, Shah ND. Hospital Readmissions among Commercially Insured and Medicare Advantage Beneficiaries with Diabetes and the Impact of Severe Hypoglycemic and Hyperglycemic Events. Journal Of General Internal Medicine 2017, 32: 1097-1105. PMID: 28685482, PMCID: PMC5602759, DOI: 10.1007/s11606-017-4095-x.Peer-Reviewed Original ResearchConceptsDiabetes Complications Severity IndexSevere dysglycemiaIndex hospitalizationMedicare Advantage beneficiariesRisk factorsBetter care transitionsComplications Severity IndexPost-discharge managementIndependent risk factorYounger patient ageOptumLabs Data WarehouseStrong risk factorYears of ageBackgroundHospital readmissionsDesignRetrospective analysisCause readmissionUnplanned readmissionPatient agePrior hospitalizationReadmission ratesYounger patientsHeart failureHospital readmissionSevere hypoglycemiaDiabetes complications
2015
Do Non-Clinical Factors Improve Prediction of Readmission Risk? Results From the Tele-HF Study
Krumholz HM, Chaudhry SI, Spertus JA, Mattera JA, Hodshon B, Herrin J. Do Non-Clinical Factors Improve Prediction of Readmission Risk? Results From the Tele-HF Study. JACC Heart Failure 2015, 4: 12-20. PMID: 26656140, PMCID: PMC5459404, DOI: 10.1016/j.jchf.2015.07.017.Peer-Reviewed Original ResearchConceptsReadmission ratesPatient-reported informationHeart failureHealth statusReadmission riskC-statisticRisk scorePsychosocial variablesMedical record abstractionWeeks of dischargeReadmission risk modelNon-clinical factorsCandidate risk factorsReadmission risk predictionRecord abstractionClinical variablesPatient interviewsMedical recordsRisk factorsPatientsPsychosocial informationPsychosocial characteristicsTelephone interviewsRisk predictionScores400 Emergency Department Visits for Mental Illness: Evaluation of Patterns and Risk Factors of Return Visits from Claim Database: 2005-2013
Lee S, Johnson R, Sangaralingham L, Herrin J, Campbell R. 400 Emergency Department Visits for Mental Illness: Evaluation of Patterns and Risk Factors of Return Visits from Claim Database: 2005-2013. Annals Of Emergency Medicine 2015, 66: s144. DOI: 10.1016/j.annemergmed.2015.07.436.Peer-Reviewed Original Research
2014
Effect of Age on Survival Between Open Repair and Surveillance for Small Abdominal Aortic Aneurysms
Filardo G, Lederle FA, Ballard DJ, Hamilton C, da Graca B, Herrin J, Sass DM, Johnson GR, Powell JT. Effect of Age on Survival Between Open Repair and Surveillance for Small Abdominal Aortic Aneurysms. The American Journal Of Cardiology 2014, 114: 1281-1286. PMID: 25159236, DOI: 10.1016/j.amjcard.2014.07.055.Peer-Reviewed Original ResearchConceptsAbdominal aortic aneurysmImmediate open repairAsymptomatic abdominal aortic aneurysmSmall abdominal aortic aneurysmsOpen repairAortic aneurysmEffect of ageFirst-line management strategyPooled patient-level dataNonclinical risk factorsUnited Kingdom Small Aneurysm TrialPatient-level dataLack of benefitSignificant differencesAneurysm TrialRisk factorsTreatment groupsPatientsAneurysmsLack of differenceTrialsSurvivalAgeWomenManagement trialsEffectiveness of the head CT choice decision aid in parents of children with minor head trauma: study protocol for a multicenter randomized trial
Hess EP, Wyatt KD, Kharbanda AB, Louie JP, Dayan PS, Tzimenatos L, Wootton-Gorges SL, Homme JL, RN L, LeBlanc A, Westphal JJ, Shepel K, Shah ND, Branda M, Herrin J, Montori VM, Kuppermann N. Effectiveness of the head CT choice decision aid in parents of children with minor head trauma: study protocol for a multicenter randomized trial. Trials 2014, 15: 253. PMID: 24965659, PMCID: PMC4081461, DOI: 10.1186/1745-6215-15-253.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryDiverse emergency departmentsMinor head traumaCranial CT scanHead traumaEmergency departmentCT scanUsual careHealthcare utilizationParents of childrenImportant traumatic brain injuryMethods/designThisProportion of patientsBlunt head traumaHospital billing recordsPatient-centered outcomesClinical prediction ruleAvailable diagnostic optionsHead CT scanDecision aidElectronic medical recordsClinician surveyMulticenter trialMedical recordsRisk factors
2013
Immediate Open Repair vs Surveillance in Patients with Small Abdominal Aortic Aneurysms: Survival Differences by Aneurysm Size
Filardo G, Lederle FA, Ballard DJ, Hamilton C, da Graca B, Herrin J, Harbor J, VanBuskirk JB, Johnson GR, Powell JT. Immediate Open Repair vs Surveillance in Patients with Small Abdominal Aortic Aneurysms: Survival Differences by Aneurysm Size. Mayo Clinic Proceedings 2013, 88: 910-919. PMID: 24001483, DOI: 10.1016/j.mayocp.2013.05.014.Peer-Reviewed Original ResearchConceptsImmediate open repairAbdominal aortic aneurysmOpen repairSurvival differencesAAA sizeSurvival benefitAortic aneurysmUK Small Aneurysm TrialAsymptomatic abdominal aortic aneurysmLarge abdominal aortic aneurysmSmall asymptomatic abdominal aortic aneurysmsSmall abdominal aortic aneurysmsImmediate endovascular repairNonclinical risk factorsSignificant survival benefitFirst-line managementSignificant survival differenceProportional hazards modelEndovascular repairSurveillance patientsAdjusted analysisStudy cohortAneurysm TrialRecent trialsRisk factors
2010
Variation in Recovery
Lichtman JH, Lorenze NP, D'Onofrio G, Spertus JA, Lindau ST, Morgan TM, Herrin J, Bueno H, Mattera JA, Ridker PM, Krumholz HM. Variation in Recovery. Circulation Cardiovascular Quality And Outcomes 2010, 3: 684-693. PMID: 21081748, PMCID: PMC3064946, DOI: 10.1161/circoutcomes.109.928713.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionYoung AMI patientsAMI patientsYoung womenHeart diseaseSex differencesExcess mortality riskIschemic heart diseaseRisk stratification modelPsychosocial risk factorsYears of ageQuality of careComparison cohortPrognostic factorsPrognostic importanceAMI populationMyocardial infarctionRisk factorsObservational studyMortality riskHigh riskAMI eventsPatientsAge accountWomenThe Effect of How Outcomes Are Framed on Decisions about Whether to Take Antihypertensive Medication: A Randomized Trial
Carling CL, Kristoffersen DT, Oxman AD, Flottorp S, Fretheim A, Schünemann HJ, Akl EA, Herrin J, MacKenzie TD, Montori VM. The Effect of How Outcomes Are Framed on Decisions about Whether to Take Antihypertensive Medication: A Randomized Trial. PLOS ONE 2010, 5: e9469. PMID: 20209127, PMCID: PMC2830888, DOI: 10.1371/journal.pone.0009469.Peer-Reviewed Original ResearchConceptsAntihypertensive medicationsVisual analog scaleCardiovascular diseaseVAS scoresRelative importance scoresCVD risk reductionYear old manLow baseline riskDetailed patient informationRandomized trialsAnalog scaleRisk factorsBaseline riskMedicationsAdult volunteersHypertensionLogistic regressionPatient informationSignificant decreaseTrialsSignificant differencesRisk reductionPresentationParticipantsRisk