2024
The Adult Changes in Thought (ACT) Medical Records Abstraction Project: A Resource for Research on Biological, Psychosocial and Behavioral Factors on the Aging Brain and Alzheimer’s Disease and Related Dementias
Gatto N, Renz A, Tom S, Lyons M, Macuiba J, Dodd T, Lind B, Gray S, Meyers K, Larson E, Nelson J, McEvoy L, Sankaran S, Key D, Litondo J, Crane P. The Adult Changes in Thought (ACT) Medical Records Abstraction Project: A Resource for Research on Biological, Psychosocial and Behavioral Factors on the Aging Brain and Alzheimer’s Disease and Related Dementias. Brain Sciences 2024, 14: 1075. DOI: 10.3390/brainsci14111075.Peer-Reviewed Original ResearchAdult ChangesMembers of Kaiser Permanente WashingtonKaiser Permanente WashingtonAbstracted medical recordsMedical recordsOlder adult membersProspective cohort studyWomen's healthRelated dementiaEpidemiological researchPharmacy dataLongitudinal clinical dataCohort studyAbstracted dataMedical conditionsBehavioral factorsAlzheimer's diseasePhysical injuryDementiaParticipantsBrain autopsyBlood pressureEpidemiological investigationsPsychosocialAct dataComparison of brain imaging and physical health between research and clinical neuroimaging cohorts of ageing
Mossa-Basha M, Andre J, Yuh E, Hunt D, LaPiana N, Howlett B, Krakauer C, Crane P, Nelson J, DeZelar M, Meyers K, Larson E, Ralston J, Mac Donald C. Comparison of brain imaging and physical health between research and clinical neuroimaging cohorts of ageing. British Journal Of Radiology 2024, 97: 614-621. PMID: 38303547, PMCID: PMC11027291, DOI: 10.1093/bjr/tqae004.Peer-Reviewed Original ResearchConceptsCommon Data ElementsMRI groupThought (ACTClinical health measuresResearch MRIAging populationWhite matter hyperintensityPrevalence of hypertensionBrain MRI measuresMRI scansNeuroimaging cohortMRI participantsAdult ChangesPhysical healthHealth measuresOverall healthOutcome measuresResearch cohortBrain imagingWMH burdenCongestive heart failureData elementsBrainMRI measurementsMRI metrics
2023
The Adult Changes in Thought (ACT) Medical Records Abstraction Project: A resource for research on the aging brain and Alzheimer’s disease and related dementias
Crane P, Lind B, Dodd T, Lyons M, Macuiba J, Gray S, Meyers K, Kelley A, Nemerever L, Covey J, Campbell C, Lederman B, Sheridan L, Tom S, Larson E, Nelson J, LaCroix A, Renz A. The Adult Changes in Thought (ACT) Medical Records Abstraction Project: A resource for research on the aging brain and Alzheimer’s disease and related dementias. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.079041.Peer-Reviewed Original ResearchMedical recordsClinical dataMedical conditionsAlzheimer's diseaseAdult ChangesElectronic medical record dataProspective cohort studyClinical-pathological correlationChart review dataLaboratory dataMedical record dataLongitudinal clinical dataAutopsy cohortCerebrovascular accidentCohort studyBlood pressureMedication dataPharmacy dataDementia statusCardiovascular conditionsNeurological conditionsDementia diagnosisAbstract medical recordsPsychiatric conditionsAnalysis of association