Association of Posttraumatic Epilepsy With 1-Year Outcomes After Traumatic Brain Injury
Burke J, Gugger J, Ding K, Kim JA, Foreman B, Yue JK, Puccio AM, Yuh EL, Sun X, Rabinowitz M, Vassar MJ, Taylor SR, Winkler EA, Deng H, McCrea M, Stein MB, Robertson CS, Levin HS, Dikmen S, Temkin NR, Barber J, Giacino JT, Mukherjee P, Wang KKW, Okonkwo DO, Markowitz AJ, Jain S, Lowenstein D, Manley GT, Diaz-Arrastia R, , Badjatia N, Duhaime AC, Feeser VR, Gaudette E, Gopinath S, Keene CD, Korley FK, Madden C, Merchant R, Schnyer D, Zafonte R. Association of Posttraumatic Epilepsy With 1-Year Outcomes After Traumatic Brain Injury. JAMA Network Open 2021, 4: e2140191. PMID: 34964854, PMCID: PMC8717106, DOI: 10.1001/jamanetworkopen.2021.40191.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryGlasgow Coma Scale scorePosttraumatic epilepsyBrief Symptom Inventory-18Positive screening resultsCohort studyBrain injuryScreening resultsGlasgow Outcome Scale Extended scoreScale scoreInitial Glasgow Coma Scale scoreGlasgow Outcome Scale-ExtendedTraumatic Brain Injury (CENTER-TBI) studyProspective cohort studyLong-term outcomesUS trauma centersNegative screening resultsTBI common data elementsBrain Injury StudyHigher BSI scoresAntiepileptogenic therapiesPrimary outcomeTBI cohortIdentified patientsTrauma centerAdmission computed tomography radiomic signatures outperform hematoma volume in predicting baseline clinical severity and functional outcome in the ATACH‐2 trial intracerebral hemorrhage population
Haider SP, Qureshi AI, Jain A, Tharmaseelan H, Berson ER, Zeevi T, Majidi S, Filippi CG, Iseke S, Gross M, Acosta JN, Malhotra A, Kim JA, Sansing LH, Falcone GJ, Sheth KN, Payabvash S. Admission computed tomography radiomic signatures outperform hematoma volume in predicting baseline clinical severity and functional outcome in the ATACH‐2 trial intracerebral hemorrhage population. European Journal Of Neurology 2021, 28: 2989-3000. PMID: 34189814, PMCID: PMC8818333, DOI: 10.1111/ene.15000.Peer-Reviewed Original ResearchConceptsAdmission Glasgow Coma ScaleGlasgow Coma ScaleRadiomics signatureMRS scoreHematoma volumeICH volumeClinical severityNoncontrast head CT scansAdmission National InstitutesHealth Stroke ScaleRankin Scale scoreStrong associationBaseline clinical severityMedium-term outcomesIndependent validation cohortHead CT scanATACH-2 trialStroke ScaleAdmission NIHSSIndependent predictorsClinical presentationComa ScaleBaseline CTICH patientsValidation cohort