2019
PI-RADS Steering Committee: The PI-RADS Multiparametric MRI and MRI-directed Biopsy Pathway
Padhani AR, Barentsz J, Villeirs G, Rosenkrantz AB, Margolis DJ, Turkbey B, Thoeny HC, Cornud F, Haider M, Macura K, Tempany C, Verma S, Weinreb J. PI-RADS Steering Committee: The PI-RADS Multiparametric MRI and MRI-directed Biopsy Pathway. Radiology 2019, 292: 464-474. PMID: 31184561, PMCID: PMC6677282, DOI: 10.1148/radiol.2019182946.Peer-Reviewed Original ResearchConceptsBiopsy pathwayProstate cancerLife-threatening prostate cancerBiopsy-naive menNegative biopsy resultsClinical care guidelinesHigh-quality evidenceSignificant prostate cancerRoutine clinical practiceProstate Imaging ReportingGreater clinical utilityNumber of diagnosesProstate cancer detectionClinical suspicionInsignificant cancerCare guidelinesBiopsy resultsProstate biopsyTransrectal USMRI pathwayPositive health impactsNumber of menBiopsy increasesIncorporation of MRIClinical utility
2017
Negative Multiparametric Magnetic Resonance Imaging of the Prostate Predicts Absence of Clinically Significant Prostate Cancer on 12-Core Template Prostate Biopsy
Lu AJ, Syed JS, Nguyen KA, Nawaf CB, Rosoff J, Spektor M, Levi A, Humphrey PA, Weinreb JC, Schulam PG, Sprenkle PC. Negative Multiparametric Magnetic Resonance Imaging of the Prostate Predicts Absence of Clinically Significant Prostate Cancer on 12-Core Template Prostate Biopsy. Urology 2017, 105: 118-122. PMID: 28322902, DOI: 10.1016/j.urology.2017.01.048.Peer-Reviewed Original ResearchConceptsMultiparametric magnetic resonance imagingSignificant prostate cancerProstate cancerNegative predictive valueMagnetic resonance imagingSystematic TRUSNegative mpMRIProstate biopsyNegative multiparametric magnetic resonance imagingPredictive valueResonance imagingClinically Significant Prostate CancerDynamic contrast enhancement sequencesTemplate mapping biopsyPrior negative biopsySystematic prostate biopsyOverall cancer detectionProstate-specific antigenTemplate prostate biopsyProstate cancer detectionDiffusion-weighted imagingCancer detectionBiopsy naïveMapping biopsyProstate volume
2016
Prostate cancer detection rates of negative MP-MRIs.
Lu A, Nawaf C, Weinreb J, Rosoff J, Schulam P, Humphrey P, Levi A, Sprenkle P. Prostate cancer detection rates of negative MP-MRIs. Journal Of Clinical Oncology 2016, 34: 91-91. DOI: 10.1200/jco.2016.34.2_suppl.91.Peer-Reviewed Original ResearchTemplate mapping biopsyNegative predictive valueNegative MRIMapping biopsyActive surveillanceSignificant cancerProstate cancer detection rateSignificant CaPMRI-US fusion biopsyHigh negative predictive valueBiopsy-naive menPrior negative biopsyBiopsy-naïve patientsCancer detection rateProstate cancer detectionDiffusion-weighted imagingDynamic contrast enhancementNIH National InstituteNaïve patientsNegative menGleason 7High suspicionNegative biopsyPatient counselingGleason 4