2015
Familial dilated cardiomyopathy diagnosis is commonly overlooked at the time of transplant listing
Seidelmann SB, Laur O, Hwa J, Depasquale E, Bellumkonda L, Sugeng L, Pomianowski P, Testani J, Chen M, McKenna W, Jacoby D. Familial dilated cardiomyopathy diagnosis is commonly overlooked at the time of transplant listing. The Journal Of Heart And Lung Transplantation 2015, 35: 474-480. PMID: 26852066, PMCID: PMC5423783, DOI: 10.1016/j.healun.2015.12.002.Peer-Reviewed Original ResearchConceptsEnd-stage heart failureStage heart failureHeart failureUNOS registryEchocardiographic findingsUNOS databaseTeaching hospitalDetailed pedigree analysisVentricular end-diastolic dimensionPanel reactive antibody levelsTertiary care teaching hospitalLarge tertiary teaching hospitalCenter-specific dataAdvanced heart failureEnd-diastolic dimensionOrgan Sharing registryMajority of patientsNon-ischemic DCMTertiary teaching hospitalMitral valve annulusDetailed family historyTransplant listingAdult patientsClinical characteristicsUNOS data
2014
Acute Kidney Injury in the Era of Ventricular Assist Devices
Brisco M, Testani J. Acute Kidney Injury in the Era of Ventricular Assist Devices. 2014, 111-124. DOI: 10.1007/978-1-4939-1273-5_9.ChaptersAcute kidney injuryVentricular assist deviceRenal functionKidney injuryRenal dysfunctionAssist deviceDurable mechanical circulatory supportAdvanced heart failureMajority of patientsMechanical circulatory supportRenal outcomesCardiac transplantationVAD implantationVAD placementHeart failureCirculatory supportPoor prognosisDestination therapyClinical significanceSignificant burdenPatientsGreater riskDysfunctionTherapyInjury
2013
Prevalence and Prognostic Importance of Changes in Renal Function After Mechanical Circulatory Support
Brisco MA, Kimmel SE, Coca SG, Putt ME, Jessup M, Tang WW, Parikh CR, Testani JM. Prevalence and Prognostic Importance of Changes in Renal Function After Mechanical Circulatory Support. Circulation Heart Failure 2013, 7: 68-75. PMID: 24214901, PMCID: PMC4067252, DOI: 10.1161/circheartfailure.113.000507.Peer-Reviewed Original ResearchConceptsMechanical circulatory supportRenal functionCirculatory supportEarly improvementContinuous-flow devicesMechanically Assisted Circulatory SupportLarge multicenter populationSerial creatinine levelsGlomerular filtration rateMajority of patientsMulticenter populationCause mortalityInteragency RegistryAdult patientsCreatinine levelsPrognostic importancePrognostic significanceImproved prognosisFiltration ratePoor survivalSurvival disadvantageEGFRPatientsAdditional researchMechanistic basis