2001
9-cis-Retinoic acid represses transcription of the gonadotropin-releasing hormone (GnRH) gene via proximal promoter region that is distinct from all-trans-retinoic acid response element
Cho S, Chung J, Han J, Lee B, Do Han Kim, Rhee K, Kim K. 9-cis-Retinoic acid represses transcription of the gonadotropin-releasing hormone (GnRH) gene via proximal promoter region that is distinct from all-trans-retinoic acid response element. Brain Research 2001, 87: 214-222. PMID: 11245924, DOI: 10.1016/s0169-328x(01)00020-1.Peer-Reviewed Original ResearchMeSH KeywordsAlitretinoinAnimalsAntineoplastic AgentsCells, CulturedDose-Response Relationship, DrugGene Expression RegulationGonadotropin-Releasing HormoneLigandsPromoter Regions, GeneticRatsReceptors, Retinoic AcidRetinoid X ReceptorsRNA, MessengerTranscription FactorsTranscription, GeneticTransfectionTretinoinConceptsGT1-1 cellsRat GnRH promoterPromoter-driven luciferase activityRetinoid X receptorTrans-RAGnRH expressionGnRH transcriptionLuciferase activityImmortalized GnRH neuronsRXR beta expressionGnRH promoterVehicle-treated controlsGnRH mRNA levelsGonadotropin-releasing hormone gene transcriptionGnRH gene expressionGonadotropin-releasing hormone (GnRH) geneTime-related mannerGnRH promoter activityTrans retinoic acidGnRH gene transcriptionTime-dependent mannerGnRH neuronsPresent studyBeta expressionResponse element
2000
Activation of retinoic acid receptor γ induces proliferation of immortalized hippocampal progenitor cells
Chung J, Cho S, Kwon Y, Do Han Kim, Kim K. Activation of retinoic acid receptor γ induces proliferation of immortalized hippocampal progenitor cells. Brain Research 2000, 83: 52-62. PMID: 11072095, DOI: 10.1016/s0169-328x(00)00196-0.Peer-Reviewed Original ResearchAlitretinoinAnimalsAntineoplastic AgentsApoptosisBcl-2-Associated X ProteinCell DivisionCell Line, TransformedCell SurvivalCulture Media, Serum-FreeDose-Response Relationship, DrugGene ExpressionHippocampusProto-Oncogene ProteinsProto-Oncogene Proteins c-bcl-2RatsReceptors, Retinoic AcidRetinoidsRNA, MessengerStem CellsTretinoin