2023
Use of overnight metyrapone test in suspected secondary adrenal insufficiency: A retrospective single centre‐study
Saini J, Garcia R, Herndon J, Erickson D, Gruber L, Bancos I. Use of overnight metyrapone test in suspected secondary adrenal insufficiency: A retrospective single centre‐study. Clinical Endocrinology 2023, 100: 203-211. PMID: 37997487, PMCID: PMC10872941, DOI: 10.1111/cen.14989.Peer-Reviewed Original ResearchConceptsDiagnosis of secondary adrenal insufficiencyOvernight metyrapone testSecondary adrenal insufficiencyCosyntropin stimulation testAdverse eventsAdrenal insufficiencyMetyrapone testPretest probabilityRetrospective study of adult patientsSingle-centre retrospective studyRetrospective single center studyDevelopment of adverse eventsStudy of adult patientsSingle center studyModerate pretest probabilityAdult patientsStimulation testCenter studyPatientsInsufficiencyDiagnosisCosyntropinSAT300 Use of Overnight Metyrapone Test In Suspected Adrenal Insufficiency: A Retrospective Single Center-Study
Saini J, Garcia R, Herndon J, Erickson D, Gruber L, Bancos I. SAT300 Use of Overnight Metyrapone Test In Suspected Adrenal Insufficiency: A Retrospective Single Center-Study. Journal Of The Endocrine Society 2023, 7: bvad114.304. PMCID: PMC10554100, DOI: 10.1210/jendso/bvad114.304.Peer-Reviewed Original ResearchDiagnosis of secondary adrenal insufficiencyOvernight metyrapone testSecondary adrenal insufficiencyCosyntropin stimulation testPre-test probabilityAdrenal insufficiencyMetyrapone testSingle center retrospective studyRetrospective single center studyExogenous glucocorticoid useSuspected adrenal insufficiencyChronic opioid useSingle center studyEvaluation of symptomsOvernight metyraponeMedian doseGlucocorticoid useOpioid useRetrospective studyStimulation testAdverse eventsCenter studyCortisol suppressionPatientsRisk factors
2022
LBSAT59 Overnight Metyrapone Test And Urine Steroid Profiling In Patients Treated With Chronic Opioid Therapy: Prevalence Of Adrenal Insufficiency
Saini J, Gilliam W, Cunningham J, Thangamuthu K, Gruber L, Singh S, Sutor B, Hooten W, Bancos I. LBSAT59 Overnight Metyrapone Test And Urine Steroid Profiling In Patients Treated With Chronic Opioid Therapy: Prevalence Of Adrenal Insufficiency. Journal Of The Endocrine Society 2022, 6: a45-a46. PMCID: PMC9626924, DOI: 10.1210/jendso/bvac150.094.Peer-Reviewed Original ResearchOpioid-induced adrenal insufficiencyOvernight metyrapone testUrine steroid profileMetyrapone testExposure to opioidsDehydroepiandrosterone sulfateSteroid profileOpioid therapyAdrenal insufficiencyDiagnosis of adrenal disordersPrevalence of adrenal insufficiencyPatients treated with opioidsMorphine milligram equivalents (MME)/dayTreated with high dosesChronic opioid therapyMeasurement of ACTHDehydroepiandrosterone sulfate concentrationsCumulative opioid exposureQuality-of-life surveyChronic opioidsCross-sectional studyOpioid exposureAdrenal disordersSteroid metabolomeDaily MME