2024
Steroid Profiling and Circadian Cortisol Secretion in Patients with Mild Autonomous Cortisol Secretion: A Cross-Sectional Study
Saini J, Singh S, Ebbehoj A, Zhang C, Nathani R, Fell V, Atkinson E, Achenbach S, Rivard A, Singh R, Grebe S, Bancos I. Steroid Profiling and Circadian Cortisol Secretion in Patients with Mild Autonomous Cortisol Secretion: A Cross-Sectional Study. The Journal Of Clinical Endocrinology & Metabolism 2024, dgae468. PMID: 38981002, DOI: 10.1210/clinem/dgae468.Peer-Reviewed Original ResearchAutonomous cortisol secretionUrine steroid metabolomeSteroid metabolomeReference subjectsCortisol secretionSteroid profileSteroid productionUrine steroid profileSubgroup of patientsArea under the curveHigh-resolution mass spectrometry assayCross-sectional studyCircadian cortisol secretionMass spectrometry assayAndrogen ratioFree cortisolSerum measurementsCircadian secretionPatientsMetabolomicsSteroidsSeparate daysUrineSecretionGlucocorticoid
2023
THU605 Impact Of Abnormal Circadian Cortisol Secretion On Bone Metabolism In Patients With Mild Autonomous Cortisol Secretion
Saini J, Nathani R, Singh S, Fell V, Atkinson E, Achenbach S, Khosla S, Bancos I. THU605 Impact Of Abnormal Circadian Cortisol Secretion On Bone Metabolism In Patients With Mild Autonomous Cortisol Secretion. Journal Of The Endocrine Society 2023, 7: bvad114.135. PMCID: PMC10554199, DOI: 10.1210/jendso/bvad114.135.Peer-Reviewed Original ResearchArea under the curveAutonomous cortisol secretionParathyroid hormoneBone metabolism biomarkersCortisol secretionFree cortisolType 1 collagenBone metabolismReference subjectsCircadian cortisol secretionCarboxy-terminal telopeptide of type 1 collagenMetabolic biomarkersMild autonomous cortisol secretionIncreased risk of fractureCross-sectional study of patientsCortisol productionParathyroid hormone productionDexamethasone suppression testRisk of fractureCarboxy-terminal telopeptideImpaired bone metabolismStudy of patientsCircadian secretory patternClinical research unitIncreased cortisol production