Neonatal hyperinsulinism in transient and classical forms of tyrosinemia
Sethuram S, Sperling MA, Gujral J, Romero CJ. Neonatal hyperinsulinism in transient and classical forms of tyrosinemia. Orphanet Journal Of Rare Diseases 2021, 16: 190. PMID: 33910593, PMCID: PMC8082838, DOI: 10.1186/s13023-020-01642-y.Peer-Reviewed Original ResearchMeSH KeywordsCongenital HyperinsulinismDiazoxideHumansHyperinsulinismInfantInfant, NewbornLiverTyrosineTyrosinemiasConceptsHyperinsulinemic hypoglycemiaMonths of lifeSpectrum of disordersRare metabolic disorderTransient tyrosinemiaDiazoxide therapyNeonatal periodPersistent hypoglycemiaInsulin secretionMaturational defectNeonatal hyperinsulinismRare caseMetabolic disordersHepatotoxic effectsPatientsBenign conditionsHereditary tyrosinemiaGenetic abnormalitiesBiochemical evaluationNovel presentationTyrosine metabolismEmbryonal originTyrosinemiaEnzyme defectFumarylacetoacetate hydrolase